CACNA1D de novo mutations in autism spectrum disorders activate Cav1.3 L-type calcium channels
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The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialGenetic disruption of voltage-gated calcium channels in psychiatric and neurological disordersTowards a Unified Theory of Calmodulin Regulation (Calmodulation) of Voltage-Gated Calcium and Sodium ChannelsL-type calcium channels as drug targets in CNS disordersL-type Calcium Channel Cav1.2 Is Required for Maintenance of Auditory Brainstem Nuclei.Sequential ionic and conformational signaling by calcium channels drives neuronal gene expression.Evaluation of genetic susceptibility of common variants in CACNA1D with schizophrenia in Han Chinese.Cell-type-specific tuning of Cav1.3 Ca(2+)-channels by a C-terminal automodulatory domain.Cav 1.3 (CACNA1D) L-type Ca(2+) channel dysfunction in CNS disordersAn autism-associated mutation in CaV1.3 channels has opposing effects on voltage- and Ca(2+)-dependent regulation.Splice variants of the CaV1.3 L-type calcium channel regulate dendritic spine morphology.Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?Regulation of Postsynaptic Stability by the L-type Calcium Channel CaV1.3 and its Interaction with PDZ ProteinsA rendezvous with the queen of ion channels: Three decades of ion channel research by David T Yue and his Calcium Signals Laboratory.Targeting voltage-gated calcium channels in neurological and psychiatric diseases.Unifying Views of Autism Spectrum Disorders: A Consideration of Autoregulatory Feedback Loops.A Polybasic Plasma Membrane Binding Motif in the I-II Linker Stabilizes Voltage-gated CaV1.2 Calcium Channel Function.L-type Ca2+ channels in mood, cognition and addiction: integrating human and rodent studies with a focus on behavioural endophenotypes.Microglial Intracellular Ca2+ Signaling in Synaptic Development and its Alterations in Neurodevelopmental Disorders.Transcriptional regulation of voltage-gated Ca2+ channels.From Gene to Behavior: L-Type Calcium Channel Mechanisms Underlying Neuropsychiatric Symptoms.Enrichment of SNPs in Functional Categories Reveals Genes Affecting Complex Traits.Exploration of the molecular mechanism of prostate cancer based on mRNA and miRNA expression profiles.Enhancing VTA Cav1.3 L-type Ca2+ channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens.A rare schizophrenia risk variant of CACNA1I disrupts CaV3.3 channel activity.Voltage-gated calcium channels - from basic mechanisms to disease.New gain-of-function mutation shows CACNA1D as recurrently mutated gene in autism spectrum disorders and epilepsy.Recurrent de novo mutations in neurodevelopmental disorders: properties and clinical implications.Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.The Contribution of L-Type Cav1.3 Channels to Retinal Light Responses.Type-1 astrocyte-like stem cells harboring Cacna1d gene deletion exhibit reduced proliferation and decreased neuronal fate choice.Identification of candidate genes involved in the etiology of sporadic Tourette syndrome by exome sequencing.Pleiotropic effects of schizophrenia-associated genetic variants in neuron firing and cardiac pacemaking revealed by computational modeling.Bilobal architecture is a requirement for calmodulin signaling to CaV1.3 channels.
P2860
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P2860
CACNA1D de novo mutations in autism spectrum disorders activate Cav1.3 L-type calcium channels
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
CACNA1D de novo mutations in a ...... Cav1.3 L-type calcium channels
@ast
CACNA1D de novo mutations in a ...... Cav1.3 L-type calcium channels
@en
type
label
CACNA1D de novo mutations in a ...... Cav1.3 L-type calcium channels
@ast
CACNA1D de novo mutations in a ...... Cav1.3 L-type calcium channels
@en
prefLabel
CACNA1D de novo mutations in a ...... Cav1.3 L-type calcium channels
@ast
CACNA1D de novo mutations in a ...... Cav1.3 L-type calcium channels
@en
P2093
P2860
P50
P921
P1476
CACNA1D de novo mutations in a ...... Cav1.3 L-type calcium channels
@en
P2093
Alexandra Pinggera
Bruno Benedetti
Michaela Lampert
Stefania Monteleone
P2860
P304
P356
10.1016/J.BIOPSYCH.2014.11.020
P407
P577
2014-12-08T00:00:00Z