Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma - Wikidata - awgldk - TriplyDB

Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma

Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma

http://www.wikidata.org/entity/Q35486521

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Biomarkers for the early diagnosis of hepatocellular carcinoma AXL kinase as a novel target for cancer therapy Elevated Serum Gas6 Is a Novel Prognostic Biomarker in Patients with Oral Squamous Cell Carcinoma.Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer Molecular Imaging of Pancreatic Cancer with Antibodies.A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics.Axl-altered microRNAs regulate tumorigenicity and gefitinib resistance in lung cancer Molecular pathways: niches in metastatic dormancy Activation of HER3 interferes with antitumor effects of Axl receptor tyrosine kinase inhibitors: suggestion of combination therapy.Promotion of glioblastoma cell motility by enhancer of zeste homolog 2 (EZH2) is mediated by AXL receptor kinase The role of epithelial plasticity in prostate cancer dissemination and treatment resistance GAS6 receptor status is associated with dormancy and bone metastatic tumor formation Inactivation of GSK3β and activation of NF-κB pathway via Axl represents an important mediator of tumorigenesis in esophageal squamous cell carcinoma.Role of α(5)β(1) Integrin Up-regulation in Radiation-Induced Invasion by Human Pancreatic Cancer Cells Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer Prognostic and Functional Significance of MAP4K5 in Pancreatic Cancer.Clinical, Pathological, and Molecular Features of Lung Adenocarcinomas with AXL Expression.Axl Expression Stratifies Patients with Poor Prognosis after Hepatectomy for Hepatocellular Carcinoma.Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis The expression of Axl receptor tyrosine kinase influences the tumour phenotype and clinical outcome of patients with malignant pleural mesothelioma Biology of the TAM receptors.AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma.Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy.Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow.Axl promotes the proliferation, invasion and migration of Wilms' tumor and can be used as a prognostic factor.Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells.Expression of Axl and its prognostic significance in human breast cancer.AXL induces epithelial-to-mesenchymal transition and regulates the function of breast cancer stem cells.Molecular insights of Gas6/TAM in cancer development and therapy.Macrophage-tumor crosstalk: role of TAMR tyrosine kinase receptors and of their ligands.The receptor tyrosine kinase Axl in cancer: biological functions and therapeutic implications.Gene of the month: Axl.Axl as a downstream effector of TGF-β1 via PI3K/Akt-PAK1 signaling pathway promotes tumor invasion and chemoresistance in breast carcinoma.Gas6/Axl pathway promotes tumor invasion through the transcriptional activation of Slug in hepatocellular carcinoma.The receptor tyrosine kinase Axl regulates cell-cell adhesion and stemness in cutaneous squamous cell carcinoma.Structural elucidation of the DFG-Asp in and DFG-Asp out states of TAM kinases and insight into the selectivity of their inhibitors.Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies.Targeting Gas6/TAM in cancer cells and tumor microenvironment.The prognostic role of Gas6/Axl axis in solid malignancies: a meta-analysis and literature review.

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Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma

http://www.wikidata.org/entity/Q35486521

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

Overexpression of receptor tyr ...... ncreatic ductal adenocarcinoma

@ast

Overexpression of receptor tyr ...... ncreatic ductal adenocarcinoma

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type

label

Overexpression of receptor tyr ...... ncreatic ductal adenocarcinoma

@ast

Overexpression of receptor tyr ...... ncreatic ductal adenocarcinoma

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prefLabel

Overexpression of receptor tyr ...... ncreatic ductal adenocarcinoma

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Overexpression of receptor tyr ...... ncreatic ductal adenocarcinoma

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Overexpression of receptor tyr ...... ncreatic ductal adenocarcinoma

@en

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Asif Rashid

http://www.w3.org/2001/XMLSchema#string

Craig D Logsdon

http://www.w3.org/2001/XMLSchema#string

Douglas B Evans

http://www.w3.org/2001/XMLSchema#string

Henry F Gomez

http://www.w3.org/2001/XMLSchema#string

Hua Wang

http://www.w3.org/2001/XMLSchema#string

Huamin Wang

http://www.w3.org/2001/XMLSchema#string

James L Abbruzzese

http://www.w3.org/2001/XMLSchema#string

Jason B Fleming

http://www.w3.org/2001/XMLSchema#string

Xianzhou Song

http://www.w3.org/2001/XMLSchema#string

P2860

Structural basis for Gas6-Axl signalling.

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase

Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival

Cell signaling by receptor tyrosine kinases

Overexpression of protein tyrosine kinases in human esophageal cancer

Cancer statistics, 2006

Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.

Axl-gas6 interaction counteracts E1A-mediated cell growth suppression and proapoptotic activity.

Tissue microarrays: applications in neuropathology research, diagnosis, and education.

Genetics and biology of pancreatic ductal adenocarcinoma.

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10.1002/CNCR.25483

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4

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