The liver kinase B1 is a central regulator of T cell development, activation, and metabolism. - Wikidata - awgldk - TriplyDB

The liver kinase B1 is a central regulator of T cell development, activation, and metabolism.

The liver kinase B1 is a central regulator of T cell development, activation, and metabolism.

http://www.wikidata.org/entity/Q35500559

about

Metabolic regulation of T cell differentiation and function T cell metabolism drives immunity Modulation of T Cell Metabolism and Function through Calcium Signaling Integrating canonical and metabolic signalling programmes in the regulation of T cell responses Mitochondria in the regulation of innate and adaptive immunity Fueling immunity: insights into metabolism and lymphocyte function Folliculin regulates ampk-dependent autophagy and metabolic stress survival The role of Fatty Acid oxidation in the metabolic reprograming of activated t-cells TCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complex Adenosine-mono-phosphate-activated protein kinase-independent effects of metformin in T cells Improved nucleosome-positioning algorithm iNPS for accurate nucleosome positioning from sequencing data.Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4+ T cell activation.Lkb1 maintains Treg cell lineage identity.The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function Role of T cells in malnutrition and obesity.LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer.LKB1 mediates the development of conventional and innate T cells via AMP-dependent kinase autonomous pathways.mTOR signaling, Tregs and immune modulation.mTOR Links Environmental Signals to T Cell Fate Decisions.Liver kinase B1 suppresses lipopolysaccharide-induced nuclear factor κB (NF-κB) activation in macrophages A single-nucleotide polymorphism in serine-threonine kinase 11, the gene encoding liver kinase B1, is a risk factor for multiple sclerosis mTOR and metabolic regulation of conventional and regulatory T cells.LKB1 inhibition of NF-κB in B cells prevents T follicular helper cell differentiation and germinal center formation.Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy.Aminoimidazole carboxamide ribonucleotide ameliorates experimental autoimmune uveitis GIMAP5 Deficiency Is Associated with Increased AKT Activity in T Lymphocytes.AMPK Protects Leukemia-Initiating Cells in Myeloid Leukemias from Metabolic Stress in the Bone Marrow Regulation and function of mTOR signalling in T cell fate decisions.The inflammation highway: metabolism accelerates inflammatory traffic in obesity.STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation.Distinct energy requirements for human memory CD4 T-cell homeostatic functions.AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo.Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy.Metabolic control of the Treg/Th17 axis Metabolic regulation of T lymphocytes.Fyn deficiency promotes a preferential increase in subcutaneous adipose tissue mass and decreased visceral adipose tissue inflammation.AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival.Metabolic switching and fuel choice during T-cell differentiation and memory development.AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling.

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The liver kinase B1 is a central regulator of T cell development, activation, and metabolism.

http://www.wikidata.org/entity/Q35500559

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2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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The liver kinase B1 is a centr ...... t, activation, and metabolism.

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The liver kinase B1 is a centr ...... t, activation, and metabolism.

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JIMMUNOL.1100367

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Journal of Immunology

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The liver kinase B1 is a centr ...... t, activation, and metabolism.

@en

P2093

Donte C Saucillo

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Jeffrey C Rathmell

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Julianna Blagih

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Luciana Tonelli

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Nancie J MacIver

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Russell G Jones

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Takla Griss

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P2860

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

mTOR regulates memory CD8 T-cell differentiation

TSC2 mediates cellular energy response to control cell growth and survival

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation

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4187-4198

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10.4049/JIMMUNOL.1100367

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8

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187

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51655202

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21930968

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3206094

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