LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
about
Dynein modifiers in C. elegans: light chains suppress conditional heavy chain mutantsSTRAD pseudokinases regulate axogenesis and LKB1 stabilityPhosphorylation of microtubule-associated protein tau by AMPK-related kinasesA new role of NUAK1: directly phosphorylating p53 and regulating cell proliferationAnalysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinaseBrain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cellsMO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinasesPhosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophagesA mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradationStructure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activationThe microtubule affinity regulating kinase MARK4 promotes axoneme extension during early ciliogenesis.SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasisRegulation of ploidy and senescence by the AMPK-related kinase NUAK1Characterization of an alternative splice variant of LKB1Substrate specificity and activity regulation of protein kinase MELKRole of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's diseaseSignaling by target of rapamycin proteins in cell growth controlPAK5 kinase is an inhibitor of MARK/Par-1, which leads to stable microtubules and dynamic actin.Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylationMicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cellsThe AMPK signalling pathway coordinates cell growth, autophagy and metabolismThe tuberous sclerosis complexAn emerging role for TOR signaling in mammalian tissue and stem cell physiologyReelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deploymentSpred1 and TESK1--two new interaction partners of the kinase MARKK/TAO1 that link the microtubule and actin cytoskeletonSkeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3Diabetes mellitus and metformin in hepatocellular carcinomaRegulation of exercise-stimulated glucose uptake in skeletal muscleThe Warburg effect and drug resistanceCurrent understanding of metformin effect on the control of hyperglycemia in diabetesMolecular Pathways Underlying Projection Neuron Production and Migration during Cerebral Cortical DevelopmentAMPK as a potential anticancer target - friend or foe?Emerging role of cell polarity proteins in breast cancer progression and metastasisThe PAR network: redundancy and robustness in a symmetry-breaking systemPolar delivery in plants; commonalities and differences to animal epithelial cellsAMP-activated protein kinase: a target for drugs both ancient and modernMitophagy in hematopoietic stem cells: the case for explorationAMP-activated protein kinase: an energy sensor that regulates all aspects of cell functionAMPK: a target for drugs and natural products with effects on both diabetes and cancerNutrient regulation of the mTOR complex 1 signaling pathway
P2860
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P248
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P2860
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
LKB1 is a master kinase that a ...... ubfamily, including MARK/PAR-1
@ast
LKB1 is a master kinase that a ...... ubfamily, including MARK/PAR-1
@en
LKB1 is a master kinase that a ...... ubfamily, including MARK/PAR-1
@en-gb
LKB1 is a master kinase that a ...... ubfamily, including MARK/PAR-1
@nl
type
label
LKB1 is a master kinase that a ...... ubfamily, including MARK/PAR-1
@ast
LKB1 is a master kinase that a ...... ubfamily, including MARK/PAR-1
@en
LKB1 is a master kinase that a ...... ubfamily, including MARK/PAR-1
@en-gb
LKB1 is a master kinase that a ...... ubfamily, including MARK/PAR-1
@nl
prefLabel
LKB1 is a master kinase that a ...... ubfamily, including MARK/PAR-1
@ast
LKB1 is a master kinase that a ...... ubfamily, including MARK/PAR-1
@en
LKB1 is a master kinase that a ...... ubfamily, including MARK/PAR-1
@en-gb
LKB1 is a master kinase that a ...... ubfamily, including MARK/PAR-1
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
LKB1 is a master kinase that a ...... ubfamily, including MARK/PAR-1
@en
P2093
D Grahame Hardie
Nick A Morrice
Olga Göransson
Rachel Toth
Simon A Hawley
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7600110
P407
P577
2004-02-25T00:00:00Z