Individual epigenetic status of the pathogenic D4Z4 macrosatellite correlates with disease in facioscapulohumeral muscular dystrophy.
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Transgenic Drosophila for Investigating DUX4 and FRG1, Two Genes Associated with Facioscapulohumeral Muscular Dystrophy (FSHD)Concise Review: Epigenetic Regulation of Myogenesis in Health and DiseaseSMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome.Facioscapulohumeral Dystrophy.Polycomb repressive complex 1 provides a molecular explanation for repeat copy number dependency in FSHD muscular dystrophy.Large family cohorts of lymphoblastoid cells provide a new cellular model for investigating facioscapulohumeral muscular dystrophy.CRISPR/dCas9-mediated Transcriptional Inhibition Ameliorates the Epigenetic Dysregulation at D4Z4 and Represses DUX4-fl in FSH Muscular Dystrophy.Mutations in DNMT3B Modify Epigenetic Repression of the D4Z4 Repeat and the Penetrance of Facioscapulohumeral Dystrophy.Recurrent major depression and right hippocampal volume: A bivariate linkage and association study.Morpholino-mediated Knockdown of DUX4 Toward Facioscapulohumeral Muscular Dystrophy Therapeutics.Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4.Constitutional Epi/Genetic Conditions: Genetic, Epigenetic, and Environmental Factors.Scalpel or Straitjacket: CRISPR/Cas9 Approaches for Muscular Dystrophies.SMCHD1 regulates a limited set of gene clusters on autosomal chromosomes.BET bromodomain inhibitors and agonists of the beta-2 adrenergic receptor identified in screens for compounds that inhibit DUX4 expression in FSHD muscle cells.Magnetic resonance imaging in facioscapulohumeral muscular dystrophy.Deep characterization of a common D4Z4 variant identifies biallelic DUX4 expression as a modifier for disease penetrance in FSHD2.A cre-inducible DUX4 transgenic mouse model for investigating facioscapulohumeral muscular dystrophy.Facioscapulohumeral Muscular Dystrophy.Sporadic DUX4 expression in FSHD myocytes is associated with incomplete repression by the PRC2 complex and gain of H3K9 acetylation on the contracted D4Z4 alleleA family-based study into penetrance in facioscapulohumeral muscular dystrophy type 1
P2860
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P2860
Individual epigenetic status of the pathogenic D4Z4 macrosatellite correlates with disease in facioscapulohumeral muscular dystrophy.
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Individual epigenetic status o ...... ulohumeral muscular dystrophy.
@ast
Individual epigenetic status o ...... ulohumeral muscular dystrophy.
@en
type
label
Individual epigenetic status o ...... ulohumeral muscular dystrophy.
@ast
Individual epigenetic status o ...... ulohumeral muscular dystrophy.
@en
prefLabel
Individual epigenetic status o ...... ulohumeral muscular dystrophy.
@ast
Individual epigenetic status o ...... ulohumeral muscular dystrophy.
@en
P2093
P2860
P50
P1433
P1476
Individual epigenetic status o ...... ulohumeral muscular dystrophy.
@en
P2093
Charles P Emerson
Jeffrey B Miller
Jennifer C J Chen
Kathryn R Wagner
Mary Lou Beermann
Oliver D King
Sachiko Homma
P2860
P2888
P356
10.1186/S13148-015-0072-6
P577
2015-03-29T00:00:00Z
P5875
P6179
1010659712