Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
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Mitochondrial Dysfunction in Alzheimer's Disease and the Rationale for Bioenergetics Based TherapiesAn overview on therapeutics attenuating amyloid β level in Alzheimer's disease: targeting neurotransmission, inflammation, oxidative stress and enhanced cholesterol levelsAlterations in Mitochondrial Quality Control in Alzheimer's DiseaseA review on mitochondrial restorative mechanism of antioxidants in Alzheimer's disease and other neurological conditionsMitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer's DiseaseDiverse molecular targets for therapeutic strategies in Alzheimer's diseaseMitochondria-Targeted Protective Compounds in Parkinson's and Alzheimer's DiseasesMitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic interventionNovel mitochondrial targets for neuroprotectionMitochondrial genome changes and neurodegenerative diseasesMitochondrial oxidative stress in aging and healthspanA γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APPEstrogen amelioration of Aβ-induced defects in mitochondria is mediated by mitochondrial signaling pathway involving ERβ, AKAP and Drp1.Human A53T α-synuclein causes reversible deficits in mitochondrial function and dynamics in primary mouse cortical neuronsThree dimensions of the amyloid hypothesis: time, space and 'wingmen'Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damageMitochondrial defects and oxidative stress in Alzheimer disease and Parkinson diseaseTargeting mitochondrial cardiolipin and the cytochrome c/cardiolipin complex to promote electron transport and optimize mitochondrial ATP synthesisFirst-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergeticsSerendipity and the discovery of novel compounds that restore mitochondrial plasticityParkin-mediated mitophagy in mutant hAPP neurons and Alzheimer's disease patient brainsMitochondrial lipids in neurodegenerationCentral presynaptic terminals are enriched in ATP but the majority lack mitochondriaNicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession.AP39, a Mitochondria-Targeted Hydrogen Sulfide Donor, Supports Cellular Bioenergetics and Protects against Alzheimer's Disease by Preserving Mitochondrial Function in APP/PS1 Mice and NeuronsMitochondria in Alzheimer's Disease and Diabetes-Associated Neurodegeneration: License to Heal!Oxidative stress and mitochondrial dysfunction in Alzheimer's disease.Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.Mitochondrial DNA damage in a mouse model of Alzheimer's disease decreases amyloid beta plaque formationOxidative Stress, Synaptic Dysfunction, and Alzheimer's Disease.Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the APP/Ld transgenic mouse model of Alzheimer's disease.Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay.New Therapeutics to Modulate Mitochondrial Function in Neurodegenerative Disorders.Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease.Cigarette smoke-induced mitochondrial fragmentation and dysfunction in human airway smooth muscle.The neuroprotective effect of Klotho is mediated via regulation of members of the redox system.Crucial role of calbindin-D28k in the pathogenesis of Alzheimer's disease mouse model.Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease.Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neuronsMitochondrial oxygen consumption deficits in skeletal muscle isolated from an Alzheimer's disease-relevant murine model
P2860
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P2860
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Impaired mitochondrial biogene ...... e model of Alzheimer's disease
@ast
Impaired mitochondrial biogene ...... e model of Alzheimer's disease
@en
type
label
Impaired mitochondrial biogene ...... e model of Alzheimer's disease
@ast
Impaired mitochondrial biogene ...... e model of Alzheimer's disease
@en
prefLabel
Impaired mitochondrial biogene ...... e model of Alzheimer's disease
@ast
Impaired mitochondrial biogene ...... e model of Alzheimer's disease
@en
P2093
P2860
P356
P1476
Impaired mitochondrial biogene ...... e model of Alzheimer's disease
@en
P2093
Marcus J Calkins
Maria Manczak
P Hemachandra Reddy
Peizhong Mao
Ulziibat Shirendeb
P2860
P304
P356
10.1093/HMG/DDR381
P577
2011-08-25T00:00:00Z