Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease - Wikidata - awgldk - TriplyDB

Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

http://www.wikidata.org/entity/Q35532902

about

Mitochondrial Dysfunction in Alzheimer's Disease and the Rationale for Bioenergetics Based Therapies An overview on therapeutics attenuating amyloid β level in Alzheimer's disease: targeting neurotransmission, inflammation, oxidative stress and enhanced cholesterol levels Alterations in Mitochondrial Quality Control in Alzheimer's Disease A review on mitochondrial restorative mechanism of antioxidants in Alzheimer's disease and other neurological conditions Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer's Disease Diverse molecular targets for therapeutic strategies in Alzheimer's disease Mitochondria-Targeted Protective Compounds in Parkinson's and Alzheimer's Diseases Mitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic intervention Novel mitochondrial targets for neuroprotection Mitochondrial genome changes and neurodegenerative diseases Mitochondrial oxidative stress in aging and healthspan A γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP Estrogen amelioration of Aβ-induced defects in mitochondria is mediated by mitochondrial signaling pathway involving ERβ, AKAP and Drp1.Human A53T α-synuclein causes reversible deficits in mitochondrial function and dynamics in primary mouse cortical neurons Three dimensions of the amyloid hypothesis: time, space and 'wingmen'Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease Targeting mitochondrial cardiolipin and the cytochrome c/cardiolipin complex to promote electron transport and optimize mitochondrial ATP synthesis First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics Serendipity and the discovery of novel compounds that restore mitochondrial plasticity Parkin-mediated mitophagy in mutant hAPP neurons and Alzheimer's disease patient brains Mitochondrial lipids in neurodegeneration Central presynaptic terminals are enriched in ATP but the majority lack mitochondria Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession.AP39, a Mitochondria-Targeted Hydrogen Sulfide Donor, Supports Cellular Bioenergetics and Protects against Alzheimer's Disease by Preserving Mitochondrial Function in APP/PS1 Mice and Neurons Mitochondria in Alzheimer's Disease and Diabetes-Associated Neurodegeneration: License to Heal!Oxidative stress and mitochondrial dysfunction in Alzheimer's disease.Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.Mitochondrial DNA damage in a mouse model of Alzheimer's disease decreases amyloid beta plaque formation Oxidative Stress, Synaptic Dysfunction, and Alzheimer's Disease.Increased mtDNA mutations with aging promotes amyloid accumulation and brain atrophy in the APP/Ld transgenic mouse model of Alzheimer's disease.Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay.New Therapeutics to Modulate Mitochondrial Function in Neurodegenerative Disorders.Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease.Cigarette smoke-induced mitochondrial fragmentation and dysfunction in human airway smooth muscle.The neuroprotective effect of Klotho is mediated via regulation of members of the redox system.Crucial role of calbindin-D28k in the pathogenesis of Alzheimer's disease mouse model.Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease.Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons Mitochondrial oxygen consumption deficits in skeletal muscle isolated from an Alzheimer's disease-relevant murine model

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P2860

Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

http://www.wikidata.org/entity/Q35532902

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

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2011年论文

@wuu

name

Impaired mitochondrial biogene ...... e model of Alzheimer's disease

@ast

Impaired mitochondrial biogene ...... e model of Alzheimer's disease

@en

type

label

Impaired mitochondrial biogene ...... e model of Alzheimer's disease

@ast

Impaired mitochondrial biogene ...... e model of Alzheimer's disease

@en

prefLabel

Impaired mitochondrial biogene ...... e model of Alzheimer's disease

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Impaired mitochondrial biogene ...... e model of Alzheimer's disease

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P1433

Human Molecular Genetics

P1476

Impaired mitochondrial biogene ...... e model of Alzheimer's disease

@en

P2093

Marcus J Calkins

http://www.w3.org/2001/XMLSchema#string

Maria Manczak

http://www.w3.org/2001/XMLSchema#string

P Hemachandra Reddy

http://www.w3.org/2001/XMLSchema#string

Peizhong Mao

http://www.w3.org/2001/XMLSchema#string

Ulziibat Shirendeb

http://www.w3.org/2001/XMLSchema#string

P2860

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Alzheimer's disease: genes, proteins, and therapy

Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases

Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons

Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent

Tau reduction prevents Abeta-induced defects in axonal transport.

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

Alzheimer's disease is a synaptic failure

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4515-4529

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scholarly article

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10.1093/HMG/DDR381

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23

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20

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2011-08-25T00:00:00Z

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51601295

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21873260

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Alzheimer's disease

P932

3209824

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