Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice. - Wikidata - awgldk - TriplyDB

Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

http://www.wikidata.org/entity/Q35535899

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Biochemical Genetic Pathways that Modulate Aging in Multiple Species Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production?Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis.Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS).Mouse Models of Oxidative Stress Indicate a Role for Modulating Healthy Aging.Effects of transgenic methionine sulfoxide reductase A (MsrA) expression on lifespan and age-dependent changes in metabolic function in mice Genetic determinants of phosphate response in Drosophila.Aging impairs induction of redox factor-1 after heat stress: a potential mechanism for heat-induced liver injury.Physiological phenotype and vulnerability in Parkinson's disease Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells.Resistance to genotoxic stresses in Arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype?In vitro susceptibility of thioredoxins and glutathione to redox modification and aging-related changes in skeletal muscle.Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging.Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.Involvement of redox state in the aging of Drosophila melanogaster.Thioredoxin, oxidative stress, cancer and aging.A midlife crisis for the mitochondrial free radical theory of aging.Revisiting an age-old question regarding oxidative stress.Thioredoxin as a putative biomarker and candidate target in age-related immune decline.Mitochondrial thioredoxin reductase 2 is elevated in long-lived primate as well as rodent species and extends fly mean lifespan Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging.Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice.Reduction of glucose intolerance with high fat feeding is associated with anti-inflammatory effects of thioredoxin 1 overexpression in mice.Healthy ageing and depletion of intracellular glutathione influences T cell membrane thioredoxin-1 levels and cytokine secretion.Different Mechanisms of Longevity in Long-Lived Mouse and Caenorhabditis elegans Mutants Revealed by Statistical Analysis of Mortality Rates.Differences in Reperfusion-Induced Mitochondrial Oxidative Stress and Cell Death Between Hippocampal CA1 and CA3 Subfields Are Due to the Mitochondrial Thioredoxin System.An Extract from the Plant Deschampsia antarctica Protects Fibroblasts from Senescence Induced by Hydrogen Peroxide.Tumour promotion versus tumour suppression in chronic hepatic iron overload.Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.Targeting Mitochondria to Counteract Age-Related Cellular Dysfunction.The Good, the Bad, and the Ugly of ROS: New Insights on Aging and Aging-Related Diseases from Eukaryotic and Prokaryotic Model Organisms.Continuous overexpression of thioredoxin 1 enhances cancer development and does not extend maximum lifespan in male C57BL/6 mice

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P2860

Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

http://www.wikidata.org/entity/Q35535899

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

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Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

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type

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Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

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Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

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Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

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Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

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The Journals of Gerontology

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Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

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P2093

Alex Bokov

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Arlan Richardson

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Asish Chaudhuri

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Celeste R Webb

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Christie M Lew

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Dean Jones

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Gene B Hubbard

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Junji Yodoi

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Kaoru Tominaga

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Lisa A Cortez

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P2860

Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

ATL-derived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction

Enzymatic reduction of protein-bound methionine sulfoxide

Is the oxidative stress theory of aging dead?

A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

The isoprostanes. Current knowledge and directions for future research

The histology and development of hepatic nodules and carcinoma in C3H/He and C57BL/6 mice following chronic phenobarbitone administration

Knockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stress

P304

1286-1299

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scholarly article

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10.1093/GERONA/GLR125

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12

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66

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Holly Van Remmen

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2011-08-26T00:00:00Z

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51601619

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21873593

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