Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage
about
High-dose irradiation induces cell cycle arrest, apoptosis, and developmental defects during Drosophila oogenesisTATA binding protein associated factor 3 (TAF3) interacts with p53 and inhibits its functionModulation of ionizing radiation-induced apoptosis by bantam microRNA in DrosophilaIrofulven induces replication-dependent CHK2 activation related to p53 statusEpigenetic telomere protection by Drosophila DNA damage response pathwaysStructural evolution of C-terminal domains in the p53 familyProtein-protein interactions more conserved within species than across speciesKdm5/Lid Regulates Chromosome Architecture in Meiotic Prophase I Independently of Its Histone Demethylase ActivityThe p53-Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humansPhylogeny and function of the invertebrate p53 superfamilyWhole-Genome Sequencing and iPLEX MassARRAY Genotyping Map an EMS-Induced Mutation Affecting Cell Competition in Drosophila melanogasterMeiotic recombination provokes functional activation of the p53 regulatory network.The FHA domain determines Drosophila Chk2/Mnk localization to key mitotic structures and is essential for early embryonic DNA damage responses.Contribution of growth and cell cycle checkpoints to radiation survival in DrosophilaDrosophila brca2 is required for mitotic and meiotic DNA repair and efficient activation of the meiotic recombination checkpointA long-term flow cytometry assay to analyze the role of specific genes of Drosophila melanogaster S2 cells in surviving genotoxic stress.Suppressor of gamma response 1 (SOG1) encodes a putative transcription factor governing multiple responses to DNA damage.E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage.Heterochromatic genome stability requires regulators of histone H3 K9 methylationGenetic control of programmed cell death during animal development.Drosophila melanogaster p53 has developmental stage-specific and sex-specific effects on adult life span indicative of sexual antagonistic pleiotropy.Menin links the stress response to genome stability in Drosophila melanogasterA DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration.Chk2 and p53 are haploinsufficient with dependent and independent functions to eliminate cells after telomere loss.Tau Ser262 phosphorylation is critical for Abeta42-induced tau toxicity in a transgenic Drosophila model of Alzheimer's disease.The homologous Drosophila transcriptional adaptors ADA2a and ADA2b are both required for normal development but have different functions.p63 and p73, the ancestors of p53.Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenanceThe role of MOF in the ionizing radiation response is conserved in Drosophila melanogasterLow levels of p53 protein and chromatin silencing of p53 target genes repress apoptosis in Drosophila endocycling cells.Nucleolar stress with and without p53.mir-11 limits the proapoptotic function of its host gene, dE2f1A role for Drosophila Cyclin J in oogenesis revealed by genetic interactions with the piRNA pathwayGenome-wide expression analysis identifies a modulator of ionizing radiation-induced p53-independent apoptosis in Drosophila melanogasterS phase-coupled E2f1 destruction ensures homeostasis in proliferating tissues.A transcriptome analysis suggests apoptosis-related signaling pathways in hemocytes of Spodoptera litura after parasitization by Microplitis bicoloratusNeuroprotection and repair of 3'-blocking DNA ends by glaikit (gkt) encoding Drosophila tyrosyl-DNA phosphodiesterase 1 (TDP1).P53-mediated rapid induction of apoptosis conveys resistance to viral infection in Drosophila melanogaster.Differential usage of alternative pathways of double-strand break repair in Drosophila.Drosophila Chk2 and p53 proteins induce stage-specific cell death independently during oogenesis.
P2860
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P2860
Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Drosophila melanogaster MNK/Ch ...... pathways following DNA damage
@ast
Drosophila melanogaster MNK/Ch ...... pathways following DNA damage
@en
type
label
Drosophila melanogaster MNK/Ch ...... pathways following DNA damage
@ast
Drosophila melanogaster MNK/Ch ...... pathways following DNA damage
@en
prefLabel
Drosophila melanogaster MNK/Ch ...... pathways following DNA damage
@ast
Drosophila melanogaster MNK/Ch ...... pathways following DNA damage
@en
P2093
P2860
P921
P1476
Drosophila melanogaster MNK/Ch ...... pathways following DNA damage
@en
P2093
Donald C Rio
Garson Tsang
Kent G Golic
Michael H Brodsky
Nadine M McGinnis
Yikang S Rong
P2860
P304
P356
10.1128/MCB.24.3.1219-1231.2004
P407
P577
2004-02-01T00:00:00Z