New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity.
about
Evolutionary Limitation and Opportunities for Developing tRNA Synthetase Inhibitors with 5-Binding-Mode ClassificationStructural and Functional Studies of Aspergillus clavatus N 5 -Carboxyaminoimidazole Ribonucleotide Synthetase,Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetaseThe Role of a Novel Auxiliary Pocket in Bacterial Phenylalanyl-tRNA Synthetase DruggabilityComparative genomics analysis of Mycobacterium ulcerans for the identification of putative essential genes and therapeutic candidatesEssentiality Assessment of Cysteinyl and Lysyl-tRNA Synthetases of Mycobacterium smegmatisChallenges of antibacterial discoveryDiscovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants.Role of the (p)ppGpp synthase RSH, a RelA/SpoT homolog, in stringent response and virulence of Staphylococcus aureus.Genome-wide Analysis of Mycoplasma hominis for the Identification of Putative Therapeutic Targets.High Throughput Screen Identifies Natural Product Inhibitor of Phenylalanyl-tRNA Synthetase from Pseudomonas aeruginosa and Streptococcus pneumoniae.Towards a comprehensive understanding of Bacillus subtilis cell physiology by physiological proteomics.Discovery and Analysis of Natural-Product Compounds Inhibiting Protein Synthesis in Pseudomonas aeruginosa.New advances in antibiotic development and discovery.Cell-free Determination of Binary Complexes That Comprise Extended Protein-Protein Interaction Networks of Yersinia pestis.Prospects for aminoacyl-tRNA synthetase inhibitors as new antimicrobial agents.Aminoacyl-tRNA synthetases: essential and still promising targets for new anti-infective agents.Proteomic signatures in antibiotic research.Overview of anti-infective drug development.Evaluation of antibacterial and antibiofilm mechanisms by usnic acid against methicillin-resistant Staphylococcus aureus.Novel targets for antibiotics in Staphylococcus aureus.Global analysis of the Staphylococcus aureus response to mupirocin.Proteomic signature of fatty acid biosynthesis inhibition available for in vivo mechanism-of-action studies.2-D Gel-Based Proteomic Approaches to Antibiotic Drug Discovery
P2860
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P2860
New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity.
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
New class of bacterial phenyla ...... y and broad-spectrum activity.
@ast
New class of bacterial phenyla ...... y and broad-spectrum activity.
@en
type
label
New class of bacterial phenyla ...... y and broad-spectrum activity.
@ast
New class of bacterial phenyla ...... y and broad-spectrum activity.
@en
prefLabel
New class of bacterial phenyla ...... y and broad-spectrum activity.
@ast
New class of bacterial phenyla ...... y and broad-spectrum activity.
@en
P2093
P2860
P1476
New class of bacterial phenyla ...... y and broad-spectrum activity.
@en
P2093
Christine Eymann
Dieter Beyer
Dieter Haebich
Guido Schiffer
Heike Brötz-Oesterhelt
Hein-Peter Kroll
Jens Pohlmann
Karl Ziegelbauer
Marcus Bauser
Michael Brands
P2860
P304
P356
10.1128/AAC.48.2.525-532.2004
P407
P577
2004-02-01T00:00:00Z