New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity. - Wikidata - awgldk - TriplyDB

New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity.

New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity.

http://www.wikidata.org/entity/Q35547361

about

Evolutionary Limitation and Opportunities for Developing tRNA Synthetase Inhibitors with 5-Binding-Mode Classification Structural and Functional Studies of Aspergillus clavatus N 5 -Carboxyaminoimidazole Ribonucleotide Synthetase,Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase The Role of a Novel Auxiliary Pocket in Bacterial Phenylalanyl-tRNA Synthetase Druggability Comparative genomics analysis of Mycobacterium ulcerans for the identification of putative essential genes and therapeutic candidates Essentiality Assessment of Cysteinyl and Lysyl-tRNA Synthetases of Mycobacterium smegmatis Challenges of antibacterial discovery Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants.Role of the (p)ppGpp synthase RSH, a RelA/SpoT homolog, in stringent response and virulence of Staphylococcus aureus.Genome-wide Analysis of Mycoplasma hominis for the Identification of Putative Therapeutic Targets.High Throughput Screen Identifies Natural Product Inhibitor of Phenylalanyl-tRNA Synthetase from Pseudomonas aeruginosa and Streptococcus pneumoniae.Towards a comprehensive understanding of Bacillus subtilis cell physiology by physiological proteomics.Discovery and Analysis of Natural-Product Compounds Inhibiting Protein Synthesis in Pseudomonas aeruginosa.New advances in antibiotic development and discovery.Cell-free Determination of Binary Complexes That Comprise Extended Protein-Protein Interaction Networks of Yersinia pestis.Prospects for aminoacyl-tRNA synthetase inhibitors as new antimicrobial agents.Aminoacyl-tRNA synthetases: essential and still promising targets for new anti-infective agents.Proteomic signatures in antibiotic research.Overview of anti-infective drug development.Evaluation of antibacterial and antibiofilm mechanisms by usnic acid against methicillin-resistant Staphylococcus aureus.Novel targets for antibiotics in Staphylococcus aureus.Global analysis of the Staphylococcus aureus response to mupirocin.Proteomic signature of fatty acid biosynthesis inhibition available for in vivo mechanism-of-action studies.2-D Gel-Based Proteomic Approaches to Antibiotic Drug Discovery

P2860

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P2860

New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity.

http://www.wikidata.org/entity/Q35547361

description

2004 nî lūn-bûn

@nan

2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

New class of bacterial phenyla ...... y and broad-spectrum activity.

@ast

New class of bacterial phenyla ...... y and broad-spectrum activity.

@en

type

label

New class of bacterial phenyla ...... y and broad-spectrum activity.

@ast

New class of bacterial phenyla ...... y and broad-spectrum activity.

@en

prefLabel

New class of bacterial phenyla ...... y and broad-spectrum activity.

@ast

New class of bacterial phenyla ...... y and broad-spectrum activity.

@en

P1433

Q35547361-5CF58DDF-A599-4DCD-9BC4-C83ADF412FAD

P1476

Q35547361-B8C46485-0B6F-44AB-8272-9FD102A125A0

P2093

Q35547361-16732F81-3752-4C88-9FB9-2A43D97644D7

Q35547361-2D09A4C7-F62D-47AF-B3D4-FB5879964CE0

Q35547361-4EBF2B35-4796-4900-BD6E-9C6D85E6D6BE

Q35547361-58F82BDB-5684-4FC5-9175-CF653B6BB587

Q35547361-6641CBE4-813C-4B03-BF18-45C984BD9516

Q35547361-6CBA7116-91CD-440B-B053-4803D239DD30

Q35547361-7C4C12CF-EEFE-4A83-90C3-415FE7C75CE6

Q35547361-94B0BA32-BB38-4130-AF3C-CA5BE1BE1ADF

Q35547361-9893DC60-70D9-470B-86CA-7AB2848D91FF

Q35547361-A4B152F6-5AE8-4ECE-BB9D-6282310925FA

P2860

Q35547361-1EBE4D69-D38C-433F-B110-7424AE4792CF

Q35547361-230D7D37-ECF2-45D2-AFFA-DA44EBCDDE4B

Q35547361-2AAB7764-4585-476B-B5E2-C20D0DE316BE

Q35547361-2EA15EBB-4763-4023-9F76-A38731FD0CD6

Q35547361-2F0B6F7D-AB8C-4575-BB09-B3B51258D6A7

Q35547361-2FC2B6C9-2221-4946-A62F-47BD9ED6DF18

Q35547361-5FE0F1B1-4D36-4DBC-B777-1EC5643C7BA2

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Q35547361-8119D67C-9B1E-45A6-A38C-080A0599FDB6

Q35547361-84399087-7221-46CD-894D-9F0EF91246EE

P304

Q35547361-8D342D8A-0067-489F-9D12-0DF8BF4AE4B3

P31

Q35547361-E7A0986E-C5B4-4A5D-9BC4-30F5BE72CAAB

P356

Q35547361-86BD4781-5E69-4F35-B6DC-016E10868313

P407

Q35547361-D0E89A9D-A8A4-4333-8E93-168DF23D835B

P433

Q35547361-F20CDDA6-EC3B-402D-A77A-013FFDA2238C

P478

Q35547361-3DA8BD21-28A8-46F8-83B0-FBED8E941897

P577

Q35547361-A923939E-0392-4ABD-99EB-2DC85D98400C

P5875

Q35547361-C6436DC6-DB2D-41F4-9534-457ABD68595F

P698

Q35547361-DB9B637C-C107-4197-8183-4CB134C7744B

P932

Q35547361-219E3B26-5BB6-4137-965F-E53C1DB24C1C

P356

AAC.48.2.525-532.2004

P1433

Antimicrobial Agents and Chemotherapy

P1476

New class of bacterial phenyla ...... y and broad-spectrum activity.

@en

P2093

Christine Eymann

http://www.w3.org/2001/XMLSchema#string

Dieter Beyer

http://www.w3.org/2001/XMLSchema#string

Dieter Haebich

http://www.w3.org/2001/XMLSchema#string

Guido Schiffer

http://www.w3.org/2001/XMLSchema#string

Heike Brötz-Oesterhelt

http://www.w3.org/2001/XMLSchema#string

Hein-Peter Kroll

http://www.w3.org/2001/XMLSchema#string

Jens Pohlmann

http://www.w3.org/2001/XMLSchema#string

Karl Ziegelbauer

http://www.w3.org/2001/XMLSchema#string

Marcus Bauser

http://www.w3.org/2001/XMLSchema#string

Michael Brands

http://www.w3.org/2001/XMLSchema#string

P2860

Human phenylalanyl-tRNA synthetase: cloning, characterization of the deduced amino acid sequences in terms of the structural domains and coordinately regulated expression of the alpha and beta subunits in chronic myeloid leukemia cells

Expression and characterization of a human mitochondrial phenylalanyl-tRNA synthetase

Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Escherichia coli by pseudomonic acid

Crystal structures of phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue

Structure of phenylalanyl-tRNA synthetase from Thermus thermophilus

The crystal structure of phenylalanyl-tRNA synthetase from thermus thermophilus complexed with cognate tRNAPhe

Evolution of aminoacyl-tRNA synthetase quaternary structure and activity: Saccharomyces cerevisiae mitochondrial phenylalanyl-tRNA synthetase.

Inhibitors of aminoacyl-tRNA synthetases as novel anti-infectives.

Root of the universal tree of life based on ancient aminoacyl-tRNA synthetase gene duplications

Resistance among Streptococcus pneumoniae: Implications for drug selection.

P304

525-532

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/AAC.48.2.525-532.2004

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

48

http://www.w3.org/2001/XMLSchema#string

P577

2004-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7954794

http://www.w3.org/2001/XMLSchema#string

P698

14742205

http://www.w3.org/2001/XMLSchema#string

P932

321521

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