Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. - Wikidata - awgldk - TriplyDB

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

http://www.wikidata.org/entity/Q35549296

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NETosis in Cancer - Platelet-Neutrophil Crosstalk Promotes Tumor-Associated Pathology The Role of Antimicrobial Peptides in Influenza Virus Infection and Their Potential as Antiviral and Immunomodulatory Therapy Directed Chemical Evolution with an Outsized Genetic Code Inhibition of NET Release Fails to Reduce Adipose Tissue Inflammation in Mice Histones as mediators of host defense, inflammation and thrombosis Lupus and proliferative nephritis are PAD4 independent in murine models.Chemical probes targeting epigenetic proteins: Applications beyond oncology.ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing.PAD4-deficiency does not affect bacteremia in polymicrobial sepsis and ameliorates endotoxemic shock Chemical biology of protein arginine modifications in epigenetic regulation DNA-Encoded Solid-Phase Synthesis: Encoding Language Design and Complex Oligomer Library Synthesis Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.DNA-encoded chemical libraries: foundations and applications in lead discovery.Diabetes primes neutrophils to undergo NETosis, which impairs wound healing.NETosis promotes cancer-associated arterial microthrombosis presenting as ischemic stroke with troponin elevation.Neutrophil elastase-deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis.Protein Arginine Methylation and Citrullination in Epigenetic Regulation Neutrophil extracellular traps - the dark side of neutrophils.Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses.Priming of neutrophils toward NETosis promotes tumor growth.Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation.Evolution of a mass spectrometry-grade protease with PTM-directed specificity.The role of extracellular histone in organ injury.PAD4: pathophysiology, current therapeutics and future perspective in rheumatoid arthritis.Neutrophil extracellular traps: protagonists of cancer progression?Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response NETs in cancer.Validation of an enzyme-linked immunosorbent assay for the quantification of citrullinated histone H3 as a marker for neutrophil extracellular traps in human plasma.Protein arginine deiminase 4 inhibition is sufficient for the amelioration of collagen-induced arthritis.NETopathies? Unraveling the Dark Side of Old Diseases through Neutrophils.A Critical Reappraisal of Neutrophil Extracellular Traps and NETosis Mimics Based on Differential Requirements for Protein Citrullination.Neutrophil-mediated vascular barrier injury: Role of neutrophil extracellular traps.Neutrophil Extracellular Traps and Its Implications in Inflammation: An Overview An emerging role for neutrophil extracellular traps in noninfectious disease.Diverse stimuli engage different neutrophil extracellular trap pathways.The Time Course of Markers of Neutrophil Extracellular Traps in Patients Undergoing Revascularisation for Acute Myocardial Infarction or Stable Angina Pectoris.PAD4 Deficiency Decreases Inflammation and Susceptibility to Pregnancy Loss in a Mouse Model.Tumor-induced neutrophil extracellular traps-drivers of systemic inflammation and vascular dysfunction.Cl-Amidine Prevents Histone 3 Citrullination and Neutrophil Extracellular Trap Formation, and Improves Survival in a Murine Sepsis Model.NETosis in cancer.

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P2860

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

http://www.wikidata.org/entity/Q35549296

description

2015 nî lūn-bûn

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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2015 թվականի հունվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

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Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

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type

label

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

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Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

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prefLabel

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

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Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

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Nature Chemical Biology

P1476

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

@en

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Cecil E Rise

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Chris Patten

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Chun-Wa Chung

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Claire Maller

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David M Wilson

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Denisa D Wagner

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Dirk Eberhard

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Gang Yao

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Gerard Joberty

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Huw D Lewis

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P2860

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Design, synthesis and selection of DNA-encoded small-molecule libraries

The development of N-α-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) i

Synthesis and Screening of a Haloacetamidine Containing Library To Identify PAD4 Selective Inhibitors

Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER

REFMAC5 for the refinement of macromolecular crystal structures

Neutrophil extracellular traps kill bacteria

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189-191

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scholarly article

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10.1038/NCHEMBIO.1735

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3

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11

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Kimberly Martinod

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2015-01-26T00:00:00Z

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25622091

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4397581

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