about
Cyclin dependent kinase 2 and the regulation of human progesterone receptor activityCyclins: roles in mitogenic signaling and oncogenic transformationDerricin and derricidin inhibit Wnt/β-catenin signaling and suppress colon cancer cell growth in vitroTargeting CDKs with Roscovitine Increases Sensitivity to DNA Damaging Drugs of Human Osteosarcoma CellsA bifunctional regulatory element in human somatic Wee1 mediates cyclin A/Cdk2 binding and Crm1-dependent nuclear export.Homeostatic response under carcinogen withdrawal, heme oxygenase 1 expression and cell cycle association.Fusobacterium nucleatum increases collagenase 3 production and migration of epithelial cells.Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury.The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity.Werner protein protects nonproliferating cells from oxidative DNA damageEffects of an Indolocarbazole-Derived CDK4 Inhibitor on Breast Cancer CellsCyclin T1 overexpression induces malignant transformation and tumor growth.ATP-noncompetitive CDK inhibitors for cancer therapy: an overview.Ibulocydine is a novel prodrug Cdk inhibitor that effectively induces apoptosis in hepatocellular carcinoma cells.Staurosporine and extracellular matrix proteins mediate the conversion of small cell lung carcinoma cells into a neuron-like phenotypeSmall molecule inhibitors targeting cyclin-dependent kinases as anticancer agents.A systems biology dynamical model of mammalian G1 cell cycle progression.Flavopiridol downregulates hypoxia-mediated hypoxia-inducible factor-1alpha expression in human glioma cells by a proteasome-independent pathway: implications for in vivo therapyClinical anticancer drug development: targeting the cyclin-dependent kinases.Oestrogen-mediated phosphorylation and stabilization of BRCA2 protein in breast.Recent progress in the discovery and development of cyclin-dependent kinase inhibitors.Recent developments in cancer chemotherapy oriented towards new targets.Signal transduction pathways that inhibit hepatitis B virus replication.Transcriptional upregulation of p57 (Kip2) by the cyclin-dependent kinase inhibitor BMS-387032 is E2F dependent and serves as a negative feedback loop limiting cytotoxicityRegulation of the G1/S phase of the cell cycle and alterations in the RB pathway in human lung cancer.Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.Effects of Auraptene on IGF-1 Stimulated Cell Cycle Progression in the Human Breast Cancer Cell Line, MCF-7.Upregulation of p27 and its inhibition of CDK2/cyclin E activity following DNA damage by a novel platinum agent are dependent on the expression of p21Phase I and pharmacologic trial of cytosine arabinoside with the selective checkpoint 1 inhibitor Sch 900776 in refractory acute leukemias.Mammalian interphase cdks: dispensable master regulators of the cell cycle.Downstream intracellular effectors of epidermal growth factor receptor as targets for anticancer therapy.Interruption of the Ras/MEK/ERK signaling cascade enhances Chk1 inhibitor-induced DNA damage in vitro and in vivo in human multiple myeloma cellsEstrogen-related receptor γ is upregulated in liver cancer and its inhibition suppresses liver cancer cell proliferation via induction of p21 and p27Phase I and pharmacologic study of SNS-032, a potent and selective Cdk2, 7, and 9 inhibitor, in patients with advanced chronic lymphocytic leukemia and multiple myeloma.The effect of the cyclin-dependent kinase inhibitor flavopiridol on anaplastic large cell lymphoma cells and relationship with NPM-ALK kinase expression and activity.Targeted therapies in the management of metastatic bladder cancerThe molecular genetics of breast cancer and targeted therapyAdvances in preclinical small molecules for the treatment of NSCLC.Emerging drugs for high-grade osteosarcoma.Novel potent pharmacological cyclin-dependent kinase inhibitors.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Small-molecule cyclin-dependent kinase modulators.
@ast
Small-molecule cyclin-dependent kinase modulators.
@en
type
label
Small-molecule cyclin-dependent kinase modulators.
@ast
Small-molecule cyclin-dependent kinase modulators.
@en
prefLabel
Small-molecule cyclin-dependent kinase modulators.
@ast
Small-molecule cyclin-dependent kinase modulators.
@en
P2860
P356
P1433
P1476
Small-molecule cyclin-dependent kinase modulators.
@en
P2093
Adrian M Senderowicz
P2860
P2888
P304
P356
10.1038/SJ.ONC.1206954
P407
P577
2003-09-01T00:00:00Z
P5875
P6179
1052100344