Transcriptional upregulation of p57 (Kip2) by the cyclin-dependent kinase inhibitor BMS-387032 is E2F dependent and serves as a negative feedback loop limiting cytotoxicity
about
EndoreplicationIncreased expression of bcl11b leads to chemoresistance accompanied by G1 accumulation.CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner.The cyclin-dependent kinase inhibitor p57(Kip2) is epigenetically regulated in carboplatin resistance and results in collateral sensitivity to the CDK inhibitor seliciclib in ovarian cancerHIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency.Maternal-fetal conflict, genomic imprinting and mammalian vulnerabilities to cancer.A small-molecule E2F inhibitor blocks growth in a melanoma culture model.Suppression of proliferation and invasive behavior of human metastatic breast cancer cells by dietary supplement BreastDefend.RhoBTB2 (DBC2) is a mitotic E2F1 target gene with a novel role in apoptosis.Knockdown of p57 gene inhibits breast cancer cell proliferation.
P2860
Q26830540-DB8142E8-B60B-4400-B6A0-D6E6F4A3C3DEQ33686984-0DE315A3-CD26-49BB-9537-3C6CC60C34D2Q33744679-3A8009C6-5679-4A15-A353-32AF4C62CE45Q35739525-C8F13B3B-847F-46B6-989C-EFB5CB540E95Q35891612-71B5CA28-46A7-4FAA-A13C-9326D15052CDQ36088017-AE1738D3-8E95-4FB3-9EAB-2251126031CAQ36737122-7F56435D-9D54-4193-AB2D-289B0C9B9141Q39647514-EF13ABAA-8BCE-4EC7-9813-36FD962AAD16Q40044467-904AD5A9-1112-4AF7-A850-5E01FB529DF2Q55372256-ED7ED47D-56BE-455C-BC48-720CD785B349
P2860
Transcriptional upregulation of p57 (Kip2) by the cyclin-dependent kinase inhibitor BMS-387032 is E2F dependent and serves as a negative feedback loop limiting cytotoxicity
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Transcriptional upregulation o ...... ack loop limiting cytotoxicity
@ast
Transcriptional upregulation o ...... ack loop limiting cytotoxicity
@en
type
label
Transcriptional upregulation o ...... ack loop limiting cytotoxicity
@ast
Transcriptional upregulation o ...... ack loop limiting cytotoxicity
@en
prefLabel
Transcriptional upregulation o ...... ack loop limiting cytotoxicity
@ast
Transcriptional upregulation o ...... ack loop limiting cytotoxicity
@en
P2860
P356
P1433
P1476
Transcriptional upregulation o ...... ack loop limiting cytotoxicity
@en
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210143
P407
P577
2006-12-18T00:00:00Z
P5875
P6179
1026518732