Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence.
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Pathogenesis and treatment of oral candidosisCandida albicans possesses Sap7 as a pepstatin A-insensitive secreted aspartic proteaseGene overexpression/suppression analysis of candidate virulence factors of Candida albicans.A novel immune evasion strategy of candida albicans: proteolytic cleavage of a salivary antimicrobial peptide.Candida albicans RIM101 pH response pathway is required for host-pathogen interactions.Overexpression of a dominant-negative allele of SEC4 inhibits growth and protein secretion in Candida albicansCandida albicans virulence and drug-resistance requires the O-acyltransferase Gup1p.Host cell invasion and virulence mediated by Candida albicans Ssa1.Roles of the Candida albicans mitogen-activated protein kinase homolog, Cek1p, in hyphal development and systemic candidiasisSecreted aspartyl proteinases and interactions of Candida albicans with human endothelial cells.Candida albicans-secreted aspartic proteinases modify the epithelial cytokine response in an in vitro model of vaginal candidiasisPotential role of phospholipases in virulence and fungal pathogenesis.In vivo analysis of secreted aspartyl proteinase expression in human oral candidiasisEffective photosensitization and selectivity in vivo of Candida Albicans by meso-tetra (N-methyl-4-pyridyl) porphine tetra tosylateUnanticipated heterogeneity in growth rate and virulence among Candida albicans AAF1 null mutants.Enhanced extracellular production of aspartyl proteinase, a virulence factor, by Candida albicans isolates following growth in subinhibitory concentrations of fluconazole.Germ tubes and proteinase activity contribute to virulence of Candida albicans in murine peritonitisMisexpression of the opaque-phase-specific gene PEP1 (SAP1) in the white phase of Candida albicans confers increased virulence in a mouse model of cutaneous infection.Cell wall and secreted proteins of Candida albicans: identification, function, and expressionInduction of SAP7 correlates with virulence in an intravenous infection model of candidiasis but not in a vaginal infection model in miceTranscriptional regulators Cph1p and Efg1p mediate activation of the Candida albicans virulence gene SAP5 during infectionDisruption of the Candida albicans TPS2 gene encoding trehalose-6-phosphate phosphatase decreases infectivity without affecting hypha formation.Secreted aspartic protease cleavage of Candida albicans Msb2 activates Cek1 MAPK signaling affecting biofilm formation and oropharyngeal candidiasis.Candidalysin is a fungal peptide toxin critical for mucosal infectionMetabolism in fungal pathogenesis.Candida albicans OPI1 regulates filamentous growth and virulence in vaginal infections, but not inositol biosynthesis.The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epithelium.Host cell invasion in mucormycosis: role of ironCandida albicans secreted aspartyl proteinases in virulence and pathogenesisA triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence.Secretory Aspartyl Proteinases Cause Vaginitis and Can Mediate Vaginitis Caused by Candida albicans in Mice.Disruption of the subtilase gene, albin1, in Ophiostoma piliferumRhb1 regulates the expression of secreted aspartic protease 2 through the TOR signaling pathway in Candida albicans.The Candida albicans Exocyst Subunit Sec6 Contributes to Cell Wall Integrity and Is a Determinant of Hyphal BranchingEnvironmental sensing and signal transduction pathways regulating morphopathogenic determinants of Candida albicans.Competitive binding inhibition enzyme-linked immunosorbent assay that uses the secreted aspartyl proteinase of Candida albicans as an antigenic marker for diagnosis of disseminated candidiasisBarrier activity in Candida albicans mediates pheromone degradation and promotes matingNovel nanoscale bacteriophage-based single-domain antibodies for the therapy of systemic infection caused by Candida albicans.Candida albicans VPS4 contributes differentially to epithelial and mucosal pathogenesis.Relationship between Candida albicans virulence during experimental hematogenously disseminated infection and endothelial cell damage in vitro.
P2860
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P2860
Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Disruption of each of the secr ...... albicans attenuates virulence.
@ast
Disruption of each of the secr ...... albicans attenuates virulence.
@en
type
label
Disruption of each of the secr ...... albicans attenuates virulence.
@ast
Disruption of each of the secr ...... albicans attenuates virulence.
@en
prefLabel
Disruption of each of the secr ...... albicans attenuates virulence.
@ast
Disruption of each of the secr ...... albicans attenuates virulence.
@en
P2093
P2860
P1476
Disruption of each of the secr ...... albicans attenuates virulence
@en
P2093
P2860
P304
P407
P577
1997-09-01T00:00:00Z