Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans.
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Insulin in central nervous system: more than just a peripheral hormoneEnglerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethalityEvolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteinsExtreme-longevity mutations orchestrate silencing of multiple signaling pathwaysThe interplay between intestinal bacteria and host metabolism in health and disease: lessons from Drosophila melanogasterUnderstanding the Key to Targeting the IGF Axis in Cancer: A Biomarker AssessmentThe three genetics (nuclear DNA, mitochondrial DNA, and gut microbiome) of longevity in humans considered as metaorganismsRegulation of insulin and type 1 insulin-like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteinsGenetics, life span, health span, and the aging process in Caenorhabditis elegansTwo membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signalingPDP-1 links the TGF-β and IIS pathways to regulate longevity, development, and metabolismRedox control of senescence and age-related diseaseMechanisms of aging-related proteinopathies in Caenorhabditis elegansLongevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intakeMethionine restriction and life-span controlAdaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous systemMitochondria-ros crosstalk in the control of cell death and agingMetformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1ins-7 Gene expression is partially regulated by the DAF-16/IIS signaling pathway in Caenorhabditis elegans under celecoxib interventionMaternal protein restriction leads to early life alterations in the expression of key molecules involved in the aging process in rat offspringUrocortin 3 regulates glucose-stimulated insulin secretion and energy homeostasisOverexpression of Atg5 in mice activates autophagy and extends lifespanTowards systematic discovery of signaling networks in budding yeast filamentous growth stress response using interventional phosphorylation data.From bacteria to man: archaic proton-dependent peptide transporters at work.When stress predicts a shrinking gene pool, trading early reproduction for longevity can increase fitness, even with lower fecundity.The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor TurnoverTranscriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan.Identification of hookworm DAF-16/FOXO response elements and direct gene targets.Distinct signature of altered homeostasis in aging rod photoreceptors: implications for retinal diseases.A recent global selective sweep on the age-1 phosphatidylinositol 3-OH kinase regulator of the insulin-like signaling pathway within Caenorhabditis remanei.The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature.Arrestin and the multi-PDZ domain-containing protein MPZ-1 interact with phosphatase and tensin homolog (PTEN) and regulate Caenorhabditis elegans longevity.Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression.JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.Honey bee PTEN--description, developmental knockdown, and tissue-specific expression of splice-variants correlated with alternative social phenotypes.A high protein diet during pregnancy affects hepatic gene expression of energy sensing pathways along ontogenesis in a porcine model.Natural polymorphism in BUL2 links cellular amino acid availability with chronological aging and telomere maintenance in yeast.Tissue-specific insulin signaling in the regulation of metabolism and aging.Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries.The Shc locus regulates insulin signaling and adiposity in mammals
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P2860
Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Insulin/IGF-I-signaling pathwa ...... ongevity from yeast to humans.
@ast
Insulin/IGF-I-signaling pathwa ...... ongevity from yeast to humans.
@en
type
label
Insulin/IGF-I-signaling pathwa ...... ongevity from yeast to humans.
@ast
Insulin/IGF-I-signaling pathwa ...... ongevity from yeast to humans.
@en
prefLabel
Insulin/IGF-I-signaling pathwa ...... ongevity from yeast to humans.
@ast
Insulin/IGF-I-signaling pathwa ...... ongevity from yeast to humans.
@en
P2093
P2860
P1476
Insulin/IGF-I-signaling pathwa ...... ongevity from yeast to humans.
@en
P2093
Giuseppe Paolisso
Massimiliano Bonafè
Michelangela Barbieri
P2860
P304
P356
10.1152/AJPENDO.00296.2003
P577
2003-11-01T00:00:00Z