The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis.
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Moving towards effective therapeutic strategies for Neuronal Ceroid LipofuscinosisAttenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice.Neuroprotection and lifespan extension in Ppt1(-/-) mice by NtBuHA: therapeutic implications for INCLA tailored mouse model of CLN2 disease: A nonsense mutant for testing personalized therapies.Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesisAn anti-neuroinflammatory that targets dysregulated glia enhances the efficacy of CNS-directed gene therapy in murine infantile neuronal ceroid lipofuscinosisEDITORIAL Neuroglia as a Central Element of Neurological Diseases: An Underappreciated Target for Therapeutic InterventionBeneficial effects of gfap/vimentin reactive astrocytes for axonal remodeling and motor behavioral recovery in mice after stroke.Axonal regeneration after sciatic nerve lesion is delayed but complete in GFAP- and vimentin-deficient miceAstrogliosis.Evidence for aberrant astrocyte hemichannel activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL).Proteomic Profiling in the Brain of CLN1 Disease Model Reveals Affected Functional Modules.Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disordersRepeated Closed Head Injury in Mice Results in Sustained Motor and Memory Deficits and Chronic Cellular Changes.Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder.Neuron-astrocyte interactions in neurodegenerative diseases: Role of neuroinflammationNeuronal Injury and Glial Changes Are Hallmarks of Open Field Blast Exposure in Swine Frontal Lobe.Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis.Astrocytes and lysosomal storage diseases.Exacerbated neuronal ceroid lipofuscinosis phenotype in Cln1/5 double-knockout mice.Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence.Astrocyte barriers to neurotoxic inflammation.Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury.Astroglial vesicular network: evolutionary trends, physiology and pathophysiology.Glia in the pathogenesis of neurodegenerative diseases.Astrocytes: a central element in neurological diseases.Synergistic effects of treating the spinal cord and brain in CLN1 disease.Combination Therapies for Lysosomal Storage Diseases: A Complex Answer to a Simple Problem.Widespread Expression of a Membrane-Tethered Version of the Soluble Lysosomal Enzyme Palmitoyl Protein Thioesterase-1.Human stefin B normal and patho-physiological role: molecular and cellular aspects of amyloid-type aggregation of certain EPM1 mutants.Targeting the thrombin receptor modulates inflammation and astrogliosis to improve recovery after spinal cord injuryAnti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.Oxidative stress as a therapeutic target in globoid cell leukodystrophy.Proteomics insights into infantile neuronal ceroid lipofuscinosis (CLN1) point to the involvement of cilia pathology in the disease.Synemin is expressed in reactive astrocytes and Rosenthal fibers in Alexander disease.Astrocytosis in infantile neuronal ceroid lipofuscinosis: friend or foe?Intermediate filaments are important for astrocyte response to oxidative stress induced by oxygen-glucose deprivation and reperfusion.Stat3 mediates LIF-induced protection of astrocytes against toxic ROS by upregulating the UPC2 mRNA pool.A role for ErbB signaling in the induction of reactive astrogliosis.Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors.
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P2860
The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis.
@ast
The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis.
@en
type
label
The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis.
@ast
The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis.
@en
prefLabel
The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis.
@ast
The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis.
@en
P2093
P2860
P1476
The role of attenuated astrocyte activation in infantile neuronal ceroid lipofuscinosis.
@en
P2093
Mark S Sands
Milos Pekny
Shannon L Macauley
P2860
P304
15575-15585
P356
10.1523/JNEUROSCI.3579-11.2011
P407
P577
2011-10-01T00:00:00Z