Crosstalk between MYCN and MDM2-p53 signal pathways regulates tumor cell growth and apoptosis in neuroblastoma
about
Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosisA critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapyNoscapine induced apoptosis via downregulation of survivin in human neuroblastoma cells having wild type or null p53Didymin: an orally active citrus flavonoid for targeting neuroblastoma.A novel mechanism of crosstalk between the p53 and NFκB pathways: MDM2 binds and inhibits p65RelA.Inhibition of MDM2 homodimerization by XIAP IRES stabilizes MDM2, influencing cancer cell survival.Focal adhesion kinase and p53 synergistically decrease neuroblastoma cell survival.Targeting MYCN IRES in MYCN-amplified neuroblastoma with miR-375 inhibits tumor growth and sensitizes tumor cells to radiationDiscovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment.Molecular mechanisms of MYCN-dependent apoptosis and the MDM2-p53 pathway: an Achille's heel to be exploited for the therapy of MYCN-amplified neuroblastoma.MYC, Cell Competition, and Cell Death in Cancer: The Inseparable Triad.Recent discoveries in the cycling, growing and aging of the p53 fieldCommon drugs and treatments for cancer and age-related diseases: revitalizing answers to NCI's provocative questions.Cell survival signaling in neuroblastoma.Nardostachys jatamansi Root Extract Modulates the Growth of IMR-32 and SK-N-MC Neuroblastoma Cell Lines Through MYCN Mediated Regulation of MDM2 and p53.Novel MDM2 inhibitor SAR405838 (MI-773) induces p53-mediated apoptosis in neuroblastoma.Targeted molecular radiotherapy of pediatric solid tumors using a radioiodinated alkyl-phospholipid ether analog.CDK4 inhibition restores G(1)-S arrest in MYCN-amplified neuroblastoma cells in the context of doxorubicin-induced DNA damage.miR-34a inhibits the apoptosis of MDSCs by suppressing the expression of N-myc.Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma.
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P2860
Crosstalk between MYCN and MDM2-p53 signal pathways regulates tumor cell growth and apoptosis in neuroblastoma
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Crosstalk between MYCN and MDM ...... and apoptosis in neuroblastoma
@ast
Crosstalk between MYCN and MDM ...... and apoptosis in neuroblastoma
@en
type
label
Crosstalk between MYCN and MDM ...... and apoptosis in neuroblastoma
@ast
Crosstalk between MYCN and MDM ...... and apoptosis in neuroblastoma
@en
prefLabel
Crosstalk between MYCN and MDM ...... and apoptosis in neuroblastoma
@ast
Crosstalk between MYCN and MDM ...... and apoptosis in neuroblastoma
@en
P2093
P2860
P356
P1433
P1476
Crosstalk between MYCN and MDM ...... and apoptosis in neuroblastoma
@en
P2093
Hailong Zhang
Muxiang Zhou
P2860
P304
P356
10.4161/CC.10.17.17118
P577
2011-09-01T00:00:00Z