The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
about
A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathwayCharacterization of an E1A-CBP interaction defines a novel transcriptional adapter motif (TRAM) in CBP/p300Effects of mutant p53 expression on human 15-lipoxygenase-promoter activity and murine 12/15-lipoxygenase gene expression: evidence that 15-lipoxygenase is a mutator geneBtf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins.Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX proteinThe human tumor suppressor arf interacts with spinophilin/neurabin II, a type 1 protein-phosphatase-binding proteinHuman immunodeficiency virus type 1 Nef binds to tumor suppressor p53 and protects cells against p53-mediated apoptosis.Sp100 interacts with ETS-1 and stimulates its transcriptional activityThe deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cellsPositive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1Mdm2 and mdmX prevent ASPP1 and ASPP2 from stimulating p53 without targeting p53 for degradationCharacterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1)HDM2-binding partners: interaction with translation elongation factor EF1alpha.Wild-type p53 binds to the TATA-binding protein and represses transcriptionp38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosisPKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasisIdentification of a novel p53 functional domain that is necessary for efficient growth suppressionTip60 and p400 are both required for UV-induced apoptosis but play antagonistic roles in cell cycle progression.Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligaseBS69, a novel adenovirus E1A-associated protein that inhibits E1A transactivationA C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism.p53 mediates the negative regulation of MDM2 by orphan receptor TR3A novel ARF-binding protein (LZAP) alters ARF regulation of HDM2Repression of p53-mediated transcription by MDM2: a dual mechanismTwo domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repressionA comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome systemHIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic functionThe Mdm2 oncoprotein interacts with the cell fate regulator NumbExpression of the papillomavirus E2 protein in HeLa cells leads to apoptosisTRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivationMDM2 suppresses p73 function without promoting p73 degradationThe Fanconi anemia polypeptide FACC is localized to the cytoplasmMDMX: a novel p53-binding protein with some functional properties of MDM2Inhibition of HDM2 and activation of p53 by ribosomal protein L23Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibitionHuman TAFII31 protein is a transcriptional coactivator of the p53 proteinEssential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activationp53-dependent ceramide response to genotoxic stress
P2860
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P2860
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
description
1992 nî lūn-bûn
@nan
1992 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
The mdm-2 oncogene product for ...... s p53-mediated transactivation
@ast
The mdm-2 oncogene product for ...... s p53-mediated transactivation
@en
The mdm-2 oncogene product for ...... s p53-mediated transactivation
@nl
type
label
The mdm-2 oncogene product for ...... s p53-mediated transactivation
@ast
The mdm-2 oncogene product for ...... s p53-mediated transactivation
@en
The mdm-2 oncogene product for ...... s p53-mediated transactivation
@nl
prefLabel
The mdm-2 oncogene product for ...... s p53-mediated transactivation
@ast
The mdm-2 oncogene product for ...... s p53-mediated transactivation
@en
The mdm-2 oncogene product for ...... s p53-mediated transactivation
@nl
P2093
P3181
P1433
P1476
The mdm-2 oncogene product for ...... s p53-mediated transactivation
@en
P2093
P304
P3181
P356
10.1016/0092-8674(92)90644-R
P407
P577
1992-06-26T00:00:00Z