Homing and mobilization of hematopoietic stem cells and hematopoietic cancer cells are mirror image processes, utilizing similar signaling pathways and occurring concurrently: circulating cancer cells constitute an ideal target for concurrent treatm
about
Homing in hematopoietic stem cells: focus on regulatory role of CXCR7 on SDF1a/CXCR4 axisRegulatory systems in bone marrow for hematopoietic stem/progenitor cells mobilization and homing.AMD3100: CXCR4 antagonist and rapid stem cell-mobilizing agentBone marrow stromal cells modulate mouse ENT1 activity and protect leukemia cells from cytarabine induced apoptosisGalphas-coupled receptor signaling actively down-regulates alpha4beta1-integrin affinity: a possible mechanism for cell de-adhesion.Is prolonged stem cell mobilization detrimental for hematopoiesis?Genomic-wide analysis of lymphatic metastasis-associated genes in human hepatocellular carcinoma.Expression profile and specific network features of the apoptotic machinery explain relapse of acute myeloid leukemia after chemotherapy.Discovery of very late antigen-4 (VLA-4, alpha4beta1 integrin) allosteric antagonists.Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion.Osteopontin enhances the expression and activity of MMP-2 via the SDF-1/CXCR4 axis in hepatocellular carcinoma cell lines.A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis.The ins and outs of hematopoietic stem cells: studies to improve transplantation outcomes.Blood clot formation does not affect metastasis formation or tumor growth in a murine model of breast cancer.Carbon monoxide down-regulates α4β1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization.The evaluation of thioridazine as a hematopoietic progenitor cell mobilizing agent in healthy human subjectsBone marrow as a source of circulating CXCR4+ tissue-committed stem cells.Bone marrow as a home of heterogenous populations of nonhematopoietic stem cells.Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis.The bone marrow vascular niche: home of HSC differentiation and mobilization.Aptamer-polymer functionalized silicon nanosubstrates for enhanced recovered circulating tumor cell viability and in vitro chemosensitivity testingThe CD34-like protein PODXL and alpha6-integrin (CD49f) identify early progenitor MSCs with increased clonogenicity and migration to infarcted heart in mice.The bone marrow niche: habitat to hematopoietic and mesenchymal stem cells, and unwitting host to molecular parasites.Gene-modified bone marrow cell therapy for prostate cancer.The critical role of SDF-1/CXCR4 axis in cancer and cancer stem cells metastasis.Silencing HIF-1α reduces the adhesion and secretion functions of acute leukemia hBMSCs.microRNA regulation in megakaryocytopoiesis.CD34+ cell adhesion molecule profiles differ between patients mobilized with granulocyte-colony-stimulating factor alone and chemotherapy followed by granulocyte-colony-stimulating factor.PLZF-mediated control on c-kit expression in CD34(+) cells and early erythropoiesis.Combination therapy of an anticancer drug with the FNIII14 peptide of fibronectin effectively overcomes cell adhesion-mediated drug resistance of acute myelogenous leukemia.Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells.MicroRNA-146a and AMD3100, two ways to control CXCR4 expression in acute myeloid leukemias.Active RHOA favors retention of human hematopoietic stem/progenitor cells in their nicheAspects of VLA-4 and LFA-1 regulation that may contribute to rolling and firm adhesion.SDF-1 promotes ox-LDL induced vascular smooth muscle cell proliferation.Engineering a multicellular vascular niche to model hematopoietic cell trafficking.Dual roles of autologous CD8+ T cells in hematopoietic progenitor cell mobilization and engraftment.
P2860
Q26752632-9E16A48A-3F9D-4FF5-828D-E61ACEA84020Q27692619-66D01FE2-6200-494E-ABFF-B74434B9AB60Q28286940-30A746BF-4B9D-46A6-8FD1-D7BF3578BB44Q28483881-F15C5E47-9CA7-47AB-8CAC-DFD9EFC44B58Q33340853-2985A997-E3EA-4995-B522-13C73485D978Q33397426-AB54F7B7-FF5F-45CB-A67B-0DE1D7C3A7E1Q33399464-2B4E5516-A01C-4627-816E-03C8FC9D8A11Q33636086-A25DA47E-8A41-4A2D-B7B9-00D4430E504CQ33763221-5E5D03BB-9EC0-441D-BDCF-679F38F78AF0Q33903491-481B5AEB-0E88-4CD2-B158-4D0B57D160A9Q34016378-F17961C5-6C02-4955-9B56-45434155DE74Q34787845-AEAE8A81-F405-4B0D-B212-587CA5D9826FQ35041174-D5C7F0F0-6B43-4B31-B059-8317E781FA55Q35150734-E16BD881-69AC-4758-B086-A81C4E3BC886Q35390252-D4C6ED8B-1FEC-4A65-8BDB-DB40884C5D07Q35570535-055A89E4-0D44-408F-91A7-855272139469Q36012911-6B8D5E35-54EF-493B-B55E-61C85AC95512Q36132019-7102696D-4215-4985-A228-880FAD86DFE3Q36175129-5183AFE2-634D-4B28-988F-E215F00D4CADQ36262585-40827D64-E7C9-4506-851E-6B98DDA952C3Q36926601-0E81BB3E-04E4-41AE-9156-30711BD0B953Q37071096-571BA6BE-7E88-4790-9A81-0A4CFEA847BCQ37096553-70EFF081-5950-4564-B377-F25765346A0AQ37127252-3C887174-515F-49CB-836D-BD770CB9401CQ37321944-61B74B9A-8682-4EE8-AC01-EC39AF3C4B81Q37370837-7AA6C6B4-0803-4A2F-AF07-B2BFC6DDD821Q37930701-EA252CB9-5A2A-41B3-8B7B-8DC1CCA74EF4Q39132633-4D1FEA91-4DCE-441F-81D1-BAB4D7EB0045Q39855670-FBFE3436-67AD-4F37-BFBE-BC67462C70B7Q40059658-BCA05F91-7BA8-4001-A554-AB6F90B790DEQ40088678-7E1E6FCF-20F0-480E-BF77-8D391A1CE610Q40298036-D5BCB647-F25E-4E76-B48B-EAA50B3F0F7FQ41902730-5C273D05-F1CC-4EFC-B746-91927904592CQ42051797-A77349A9-E5AE-4A70-B47C-5170544D114DQ45924603-46D39ED8-4EED-40AD-9320-143C8CED66A6Q52345961-D69AAA77-1B89-4C00-A75E-D8A44A1A94A3Q52960329-65245D3B-FA54-46CA-8C45-1BDBAE38BFC4
P2860
Homing and mobilization of hematopoietic stem cells and hematopoietic cancer cells are mirror image processes, utilizing similar signaling pathways and occurring concurrently: circulating cancer cells constitute an ideal target for concurrent treatm
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Homing and mobilization of hem ...... l target for concurrent treatm
@ast
Homing and mobilization of hem ...... l target for concurrent treatm
@en
type
label
Homing and mobilization of hem ...... l target for concurrent treatm
@ast
Homing and mobilization of hem ...... l target for concurrent treatm
@en
prefLabel
Homing and mobilization of hem ...... l target for concurrent treatm
@ast
Homing and mobilization of hem ...... l target for concurrent treatm
@en
P2860
P356
P1433
P1476
Homing and mobilization of hem ...... l target for concurrent treatm
@en
P2093
P2860
P2888
P356
10.1038/SJ.LEU.2403173
P577
2004-01-01T00:00:00Z