Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis. - Wikidata - awgldk - TriplyDB

Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis.

Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis.

http://www.wikidata.org/entity/Q36175129

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The Role of Chemokines in Promoting Colorectal Cancer Invasion/Metastasis Chemokines and chemokine receptors: update on utility and challenges for the clinician.The inhibitory effect of doxycycline on cisplatin-sensitive and -resistant epithelial ovarian cancer CCR6 regulation of the actin cytoskeleton orchestrates human beta defensin-2- and CCL20-mediated restitution of colonic epithelial cells Simultaneous CXCL12 and ESR1 CpG island hypermethylation correlates with poor prognosis in sporadic breast cancer Abnormal DNA methylation as a cell-free circulating DNA biomarker for colorectal cancer detection: A review of literature.CXCL12 chemokine expression and secretion regulates colorectal carcinoma cell anoikis through Bim-mediated intrinsic apoptosis.COUP-TFI modifies CXCL12 and CXCR4 expression by activating EGF signaling and stimulates breast cancer cell migration.CXCL12 expression by healthy and malignant ovarian epithelial cells.Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration.Chemokines and chemokine receptors in mucosal homeostasis at the intestinal epithelial barrier in inflammatory bowel disease.Epigenetic silencing of CXCR4 promotes loss of cell adhesion in cervical cancer.Decreased expression of 17β-hydroxysteroid dehydrogenase type 1 is associated with DNA hypermethylation in colorectal cancer located in the proximal colon.Epigenetic changes of CXCR4 and its ligand CXCL12 as prognostic factors for sporadic breast cancer.Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis CXCL12-CXCR4 axis promotes the natural selection of breast cancer cell metastasis CXCL12 promoter methylation and PD-L1 expression as prognostic biomarkers in prostate cancer patients.DNA methylation and microRNA biomarkers for noninvasive detection of gastric and colorectal cancer.CXC receptor-4 mRNA silencing abrogates CXCL12-induced migration of colorectal cancer cells.Astrocytes directly influence tumor cell invasion and metastasis in vivo.CXCL12 chemokine expression suppresses human pancreatic cancer growth and metastasis.Targeted intestinal epithelial deletion of the chemokine receptor CXCR4 reveals important roles for extracellular-regulated kinase-1/2 in restitution.Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways.Survival outcomes in endometrial cancer patients are associated with CXCL12 and estrogen receptor expression.Loss of one Tgfbr2 allele in fibroblasts promotes metastasis in MMTV: polyoma middle T transgenic and transplant mouse models of mammary tumor progression.Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling Sequential genetic change at the TP53 and chemokine receptor CXCR4 locus during transformation of human ovarian surface epithelium.Epigenetics and colorectal cancer In vitro characterization and inhibition of the CXCR4/CXCL12 chemokine axis in human uveal melanoma cell lines.A meta-analysis of CXCL12 expression for cancer prognosis.CXCL12/CXCR4 axis plays pivotal roles in the organ-specific metastasis of pancreatic adenocarcinoma: A clinical study BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism.Epigenetic silencing of NTSR1 is associated with lateral and noninvasive growth of colorectal tumors.Expression of SDF-1 alpha and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer.Regulation of CXCR4 signaling.Nitric oxide regulates tumor cell cross-talk with stromal cells in the tumor microenvironment of the liver Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells The critical role of SDF-1/CXCR4 axis in cancer and cancer stem cells metastasis.Silencing speckle-type POZ protein by promoter hypermethylation decreases cell apoptosis through upregulating Hedgehog signaling pathway in colorectal cancer Epigenetic and genetic deregulation in cancer target distinct signaling pathway domains.

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P2860

Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis.

http://www.wikidata.org/entity/Q36175129

description

2006 nî lūn-bûn

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Silencing of epithelial CXCL12 ...... colonic carcinoma metastasis.

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Silencing of epithelial CXCL12 ...... colonic carcinoma metastasis.

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Silencing of epithelial CXCL12 ...... colonic carcinoma metastasis.

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Silencing of epithelial CXCL12 ...... colonic carcinoma metastasis.

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Silencing of epithelial CXCL12 ...... colonic carcinoma metastasis.

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Silencing of epithelial CXCL12 ...... colonic carcinoma metastasis.

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Involvement of chemokine receptors in breast cancer metastasis

Expression of functional CXCR4 chemokine receptors on human colonic epithelial cells

High sensitivity mapping of methylated cytosines

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

Stromal cell derived factor-1: its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer.

A genetic model for colorectal tumorigenesis

Regulated production of interferon-inducible T-cell chemoattractants by human intestinal epithelial cells

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

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