Lymphopenic mice reconstituted with limited repertoire T cells develop severe, multiorgan, Th2-associated inflammatory disease.
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Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committeep110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway InflammationAn intrinsic mechanism predisposes Foxp3-expressing regulatory T cells to Th2 conversion in vivoDifferentiation of effector CD4 T cell populations (*)Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitisChronic cigarette smoke exposure generates pathogenic T cells capable of driving COPD-like disease in Rag2-/- mice.IgE actions on CD4+ T cells, mast cells, and macrophages participate in the pathogenesis of experimental abdominal aortic aneurysms.Mislocalization of SLP-76 leads to aberrant inflammatory cytokine and autoantibody productionCD4(+) CD25(+) Foxp3(+) T regulatory cells with limited TCR diversity in control of autoimmunity.Antigen-specific peripheral shaping of the natural regulatory T cell population.Microbiota: dual-faceted player in experimental colitis.Peptide library-based evaluation of T-cell receptor breadth detects defects in global and regulatory activation in human immunologic diseases.Pathogen-sensing and regulatory T cells: integrated regulators of immune responses.Sequential class switching is required for the generation of high affinity IgE antibodies.Intestinal microbiota sustains inflammation and autoimmunity induced by hypomorphic RAG defects.Reduced TCR signaling potential impairs negative selection but does not result in autoimmune disease.Omenn syndrome associated with a functional reversion due to a somatic second-site mutation in CARD11 deficiency.Lack of p47(phox) in Akita Diabetic Mice Is Associated with Interstitial Pneumonia, Fibrosis, and Oral Inflammation.Murine models of Omenn syndromeTh1, Th2, and Th17 effector T cell-induced autoimmune gastritis differs in pathological pattern and in susceptibility to suppression by regulatory T cells.p47phox deficiency induces macrophage dysfunction resulting in progressive crystalline macrophage pneumoniaDifferential lymphopenia-induced homeostatic proliferation for CD4+ and CD8+ T cells following septic injuryCD4+CD25+Foxp3+ regulatory T cells optimize diversity of the conventional T cell repertoire during reconstitution from lymphopeniaBreakdown of T cell tolerance and autoimmunity in primary immunodeficiency--lessons learned from monogenic disorders in mice and menRespiratory viruses and eosinophils: exploring the connections.Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations.Magnetic cell sorting and flow cytometry sorting methods for the isolation and function analysis of mouse CD4+ CD25+ Treg cells.Biology and treatment of eosinophilic esophagitis.Respiratory viruses, eosinophilia and their roles in childhood asthma.Understanding eosinophilic esophagitis: the cellular and molecular mechanisms of an emerging disease.Altered T-cell receptor signaling in the pathogenesis of allergic disease.Critical influence of the thymus on peripheral T cell homeostasisInfection, eosinophilia and childhood asthma.Cutting edge: lack of high affinity competition for peptide in polyclonal CD4+ responses unmasks IL-4 production.Secondary immunologic consequences in chromosome 22q11.2 deletion syndrome (DiGeorge syndrome/velocardiofacial syndrome).Acute eosinophilic pneumonia occurring in a dedicator of cytokinesis 8 (DOCK8) deficient patient.Expansion of a restricted residual host T reg-cell repertoire is dependent on IL-2 following experimental autologous hematopoietic stem transplantation.Wiskott-Aldrich syndrome protein deficiency in innate immune cells leads to mucosal immune dysregulation and colitis in mice.Thymus transplantation restores the repertoires of forkhead box protein 3 (FoxP3)+ and FoxP3- T cells in complete DiGeorge anomaly.A humanized mouse model of anaphylactic peanut allergy.
P2860
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P2860
Lymphopenic mice reconstituted with limited repertoire T cells develop severe, multiorgan, Th2-associated inflammatory disease.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Lymphopenic mice reconstituted ...... sociated inflammatory disease.
@ast
Lymphopenic mice reconstituted ...... sociated inflammatory disease.
@en
type
label
Lymphopenic mice reconstituted ...... sociated inflammatory disease.
@ast
Lymphopenic mice reconstituted ...... sociated inflammatory disease.
@en
prefLabel
Lymphopenic mice reconstituted ...... sociated inflammatory disease.
@ast
Lymphopenic mice reconstituted ...... sociated inflammatory disease.
@en
P2093
P2860
P356
P1476
Lymphopenic mice reconstituted ...... sociated inflammatory disease.
@en
P2093
Andrea Keane-Myers
Jerrold M Ward
Joshua D Milner
William E Paul
P2860
P304
P356
10.1073/PNAS.0610289104
P407
P577
2007-01-03T00:00:00Z