Chemistry, biological activity, and chemotherapeutic potential of betulinic acid for the prevention and treatment of cancer and HIV infection.
about
Targeting cancer using cholesterol conjugatesNanotechnology-Based Drug Delivery Systems for Melanoma Antitumoral Therapy: A ReviewScreening and characterisation of antimicrobial properties of semisynthetic betulin derivativesAntileishmanial activity of semisynthetic lupane triterpenoids betulin and betulinic acid derivatives: synergistic effects with miltefosineSynthesis of antitumor-active betulinic acid-derived hydroxypropargylamines by copper-catalyzend mannich reactions.Study of the betulin enriched birch bark extracts effects on human carcinoma cells and ear inflammation.Betulin is a potent anti-tumor agent that is enhanced by cholesterol.Enhancing the divergent activities of betulinic acid via neoglycosylation.The continuing search for antitumor agents from higher plantsBetulinic acid in complex with a gamma-cyclodextrin derivative decreases proliferation and in vivo tumor development of non-metastatic and metastatic B164A5 cells.Synthesis, biology and clinical significance of pentacyclic triterpenes: a multi-target approach to prevention and treatment of metabolic and vascular diseases.Co-administration of betulinic acid and methamphetamine causes toxicity to dopaminergic and serotonergic nerve terminals in the striatum of late adolescent ratsConjugates of betulin derivatives with AZT as potent anti-HIV agents.Improving physical properties via C-H oxidation: chemical and enzymatic approachesAntiproliferative activity and apoptosis-inducing mechanism of constituents from Toona sinensis on human cancer cellsNew ionic derivatives of betulinic acid as highly potent anti-cancer agents.Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptaseThe efficacy of betulinic acid in triple-negative breast cancer.Identification of natural products with neuronal and metabolic benefits through autophagy induction.The discovery of a class of novel HIV-1 maturation inhibitors and their potential in the therapy of HIV.A piperazidine derivative of 23-hydroxy betulinic acid induces a mitochondria-derived ROS burst to trigger apoptotic cell death in hepatocellular carcinoma cells.Betulin complex in γ-cyclodextrin derivatives: properties and antineoplasic activities in in vitro and in vivo tumor models.Design, synthesis and biological evaluation of novel betulinic acid derivatives.Pre-clinical development as microbicide of zinc tetra-ascorbo-camphorate, a novel terpenoid derivative: potent in vitro inhibitory activity against both R5- and X4-tropic HIV-1 strains without significant in vivo mucosal toxicity.Plant-derived triterpenoids and analogues as antitumor and anti-HIV agentsPerspectives for cancer prevention with natural compoundsThe lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities.Cancer preventive agents 9. Betulinic acid derivatives as potent cancer chemopreventive agents.Small mitochondria-targeting molecules as anti-cancer agents.Effects of Abies sibirica terpenes on cancer- and aging-associated pathways in human cells.Biotransformations of diterpenoids and triterpenoids: a review.Betulinic Acid and its Derivatives as Potential Antitumor Agents.Betulinic Acid: Recent Advances in Chemical Modifications, Effective Delivery, and Molecular Mechanisms of a Promising Anticancer Therapy.Estrogen Receptor Signaling and the PI3K/Akt Pathway Are Involved in Betulinic Acid-Induced eNOS Activation.Effect of a Synthesized Amyl-Glycine1, 10-Phenanthroline Platinum Nitrate on Structure and Stability of Human Blood Carrier Protein, Albumin: Spectroscopic and Modeling Approaches.Characterization and in vitro studies of the anticancer effect of oxidized carbon nanotubes functionalized with betulinic acid.Synthesis and anti-HCV entry activity studies of β-cyclodextrin-pentacyclic triterpene conjugates.Production of anti-cancer triterpene (betulinic acid) from callus cultures of different Ocimum species and its elicitation.Two series of new semisynthetic triterpene derivatives: differences in anti-malarial activity, cytotoxicity and mechanism of action.Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process.
P2860
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P2860
Chemistry, biological activity, and chemotherapeutic potential of betulinic acid for the prevention and treatment of cancer and HIV infection.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Chemistry, biological activity ...... t of cancer and HIV infection.
@ast
Chemistry, biological activity ...... t of cancer and HIV infection.
@en
type
label
Chemistry, biological activity ...... t of cancer and HIV infection.
@ast
Chemistry, biological activity ...... t of cancer and HIV infection.
@en
prefLabel
Chemistry, biological activity ...... t of cancer and HIV infection.
@ast
Chemistry, biological activity ...... t of cancer and HIV infection.
@en
P921
P356
P1476
Chemistry, biological activity ...... t of cancer and HIV infection.
@en
P2093
Robert H Cichewicz
Samir A Kouzi
P304
P356
10.1002/MED.10053
P577
2004-01-01T00:00:00Z