Inhibition of human liver aldehyde oxidase: implications for potential drug-drug interactions.
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The First Mammalian Aldehyde Oxidase Crystal Structure: INSIGHTS INTO SUBSTRATE SPECIFICITYOptimization of the Expression of Human Aldehyde Oxidase for Investigations of Single-Nucleotide PolymorphismsEvidence for substrate-dependent inhibition profiles for human liver aldehyde oxidase.Potential role of cardiac calsequestrin in the lethal arrhythmic effects of cocaineInhibition of human aldehyde oxidase activity by diet-derived constituents: structural influence, enzyme-ligand interactions, and clinical relevanceA novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834Interspecies differences in the metabolism of methotrexate: An insight into the active site differences between human and rabbit aldehyde oxidasePredicting intrinsic clearance for drugs and drug candidates metabolized by aldehyde oxidase.Evaluation of rhesus monkey and guinea pig hepatic cytosol fractions as models for human aldehyde oxidase.Aldehyde oxidase functions as a superoxide generating NADH oxidase: an important redox regulated pathway of cellular oxygen radical formation.Strategies for a comprehensive understanding of metabolism by aldehyde oxidase.The role of drug metabolizing enzymes in clearance.Evaluation of a New Molecular Entity as a Victim of Metabolic Drug-Drug Interactions-an Industry Perspective.An overview of aldehyde oxidase: an enzyme of emerging importance in novel drug discovery.Toward an Understanding of Structural Insights of Xanthine and Aldehyde Oxidases: An Overview of their Inhibitors and Role in Various Diseases.Evaluating the Disposition of a Mixed Aldehyde Oxidase/Cytochrome P450 Substrate in Rats with Attenuated P450 Activity.ecoAO: A Simple System for the Study of Human Aldehyde Oxidases Role in Drug Metabolism.Identification of a suitable and selective inhibitor towards aldehyde oxidase catalyzed reactions.
P2860
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P2860
Inhibition of human liver aldehyde oxidase: implications for potential drug-drug interactions.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Inhibition of human liver alde ...... ential drug-drug interactions.
@ast
Inhibition of human liver alde ...... ential drug-drug interactions.
@en
type
label
Inhibition of human liver alde ...... ential drug-drug interactions.
@ast
Inhibition of human liver alde ...... ential drug-drug interactions.
@en
prefLabel
Inhibition of human liver alde ...... ential drug-drug interactions.
@ast
Inhibition of human liver alde ...... ential drug-drug interactions.
@en
P2860
P356
P1476
Inhibition of human liver alde ...... ential drug-drug interactions.
@en
P2093
Jeffrey P Jones
John T Barr
P2860
P304
P356
10.1124/DMD.111.041806
P577
2011-09-22T00:00:00Z