Evidence for an intrinsic toxicity of phosphatidylcholine to Sec14p-dependent protein transport from the yeast Golgi complex.
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Loss of Swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila.Cell wall integrity MAPK pathway is essential for lipid homeostasis.Cessation of growth to prevent cell death due to inhibition of phosphatidylcholine synthesis is impaired at 37 degrees C in Saccharomyces cerevisiae.Nonclassical PITPs activate PLD via the Stt4p PtdIns-4-kinase and modulate function of late stages of exocytosis in vegetative yeast.Phospholipid transfer protein Sec14 is required for trafficking from endosomes and regulates distinct trans-Golgi export pathways.Multiple functions as lipase, steryl ester hydrolase, phospholipase, and acyltransferase of Tgl4p from the yeast Saccharomyces cerevisiae.Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex.Neuropathy target esterase and its yeast homologue degrade phosphatidylcholine to glycerophosphocholine in living cells.Genetic ablation of phosphatidylinositol transfer protein function in murine embryonic stem cellsRegulation of phosphoinositide levels by the phospholipid transfer protein Sec14p controls Cdc42p/p21-activated kinase-mediated cell cycle progression at cytokinesisLoss-of-function mutations in PNPLA6 encoding neuropathy target esterase underlie pubertal failure and neurological deficits in Gordon Holmes syndrome.Phosphoinositide phosphatases in cell biology and disease.Activity of specific lipid-regulated ADP ribosylation factor-GTPase-activating proteins is required for Sec14p-dependent Golgi secretory function in yeast.Lipid metabolism and vesicle trafficking: more than just greasing the transport machinery.Localization of lipid raft proteins to the plasma membrane is a major function of the phospholipid transfer protein Sec14.Mutations that affect vacuole biogenesis inhibit proliferation of the endoplasmic reticulum in Saccharomyces cerevisiaeBiological functions of phosphatidylinositol transfer proteins.The Sec14-superfamily and the regulatory interface between phospholipid metabolism and membrane traffickingPhosphatidylinositol transfer proteins and functional specification of lipid signaling pools.Regulation of phosphatidylcholine homeostasis by Sec14.Phosphatidylinositol transfer proteins and cellular nanoreactors for lipid signaling.Surprising roles for phospholipid binding proteins revealed by high throughput genetics.Unravelling secretion in Cryptococcus neoformans: more than one way to skin a cat.Phosphatidylinositol transfer proteins: negotiating the regulatory interface between lipid metabolism and lipid signaling in diverse cellular processes.Nte1p-mediated deacylation of phosphatidylcholine functionally interacts with Sec14p.The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity.Phosphatidylinositol transfer protein beta displays minimal sphingomyelin transfer activity and is not required for biosynthesis and trafficking of sphingomyelin.NuA4 Lysine Acetyltransferase Complex Contributes to Phospholipid Homeostasis in Saccharomyces cerevisiae.Phosphatidylethanolamine has an essential role in Saccharomyces cerevisiae that is independent of its ability to form hexagonal phase structures.Phosphorylation of Saccharomyces cerevisiae choline kinase on Ser30 and Ser85 by protein kinase A regulates phosphatidylcholine synthesis by the CDP-choline pathway.Characterization and regulation of yeast Ca2+-dependent phosphatidylethanolamine-phospholipase D activity.The Yeast PhospholipidN-Methyltransferases Catalyzing the Synthesis of Phosphatidylcholine Preferentially Convert Di-C16:1 Substrates Bothin Vivoandin Vitro
P2860
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P2860
Evidence for an intrinsic toxicity of phosphatidylcholine to Sec14p-dependent protein transport from the yeast Golgi complex.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Evidence for an intrinsic toxi ...... from the yeast Golgi complex.
@ast
Evidence for an intrinsic toxi ...... from the yeast Golgi complex.
@en
type
label
Evidence for an intrinsic toxi ...... from the yeast Golgi complex.
@ast
Evidence for an intrinsic toxi ...... from the yeast Golgi complex.
@en
prefLabel
Evidence for an intrinsic toxi ...... from the yeast Golgi complex.
@ast
Evidence for an intrinsic toxi ...... from the yeast Golgi complex.
@en
P2093
P2860
P356
P1476
Evidence for an intrinsic toxi ...... from the yeast Golgi complex.
@en
P2093
P2860
P304
P356
10.1091/MBC.12.4.1117
P577
2001-04-01T00:00:00Z