Role of glucose transporters in the cellular insulin resistance of type II non-insulin-dependent diabetes mellitus
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Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscleA dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation.Pathogenesis of insulin resistance in skeletal muscle.Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic ratsCharacterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitusMolecular mechanism of insulin resistance in obesity and type 2 diabetes.Transmembrane glucose transport in skeletal muscle of patients with non-insulin-dependent diabetes.Reduced capacity and affinity of skeletal muscle for insulin-mediated glucose uptake in noninsulin-dependent diabetic subjects. Effects of insulin therapyNormalization of blood glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose transporter gene expression.Glucose transporter levels in spontaneously obese (db/db) insulin-resistant mice.Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man. A novel mechanism for insulin resistance.Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitusReversibility of defective adipocyte insulin receptor kinase activity in non-insulin-dependent diabetes mellitus. Effect of weight loss.Pretranslational suppression of a glucose transporter protein causes insulin resistance in adipocytes from patients with non-insulin-dependent diabetes mellitus and obesity.Targeting of the "insulin-responsive" glucose transporter (GLUT4) to the regulated secretory pathway in PC12 cells.The effect of non-insulin-dependent diabetes mellitus and obesity on glucose transport and phosphorylation in skeletal muscle.Exercise improved lipid metabolism and insulin sensitivity in rats fed a high-fat diet by regulating glucose transporter 4 (GLUT4) and musclin expression.Impaired tethering and fusion of GLUT4 vesicles in insulin-resistant human adipose cells.Determining the relationship between dietary carbohydrate intake and insulin resistance.Posttranslational modifications of GLUT4 affect its subcellular localization and translocation.Cellular mechanism of nutritionally induced insulin resistance: the desert rodent Psammomys obesus and other animals in which insulin resistance leads to detrimental outcome.Glucose transporters: cellular links to hyperglycemia in insulin resistance and diabetes.Rac-1 superactivation triggers insulin-independent glucose transporter 4 (GLUT4) translocation that bypasses signaling defects exerted by c-Jun N-terminal kinase (JNK)- and ceramide-induced insulin resistance.Effects of high glucose on caveolin-1 and insulin signaling in 3T3-L1 adipocytes.Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats.Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle.The glucose transporter family: structure, function and tissue-specific expression.The genetics and pathophysiology of type II and gestational diabetes.Effect of streptozotocin-induced diabetes on GLUT-4 phosphorylation in rat adipocytes.Polymorphisms at the GLUT1 (HepG2) and GLUT4 (muscle/adipocyte) glucose transporter genes and non-insulin-dependent diabetes mellitus (NIDDM).Insulin-stimulated glucose transport in muscle. Evidence for a protein-kinase-C-dependent component which is unaltered in insulin-resistant micePrognostic interaction patterns in diabetes mellitus II: A random-matrix-theory relation.Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue.Percutaneous adipose tissue biopsy by mini-liposuction for metabolic studies.Opposite translational control of GLUT1 and GLUT4 glucose transporter mRNAs in response to insulin. Role of mammalian target of rapamycin, protein kinase b, and phosphatidylinositol 3-kinase in GLUT1 mRNA translation.2-[(18)F]fluoro-2-deoxy-D-glucose combined with microdialysis can be used for the comparison of tissue glucose metabolism in obese and lean rats.The influence of down-regulation of suppressor of cellular signaling proteins by RNAi on glucose transport of intrauterine growth retardation rats.Effects of glucose and its modulation by insulin and estradiol on BMSC differentiation into osteoblastic lineages.Thyroid stimulating hormone stimulates the expression of glucose transporter 2 via its receptor in pancreatic β cell line, INS-1 cells.Muscle insulin resistance in uremic humans: glucose transport, glucose transporters, and insulin receptors.
P2860
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P2860
Role of glucose transporters in the cellular insulin resistance of type II non-insulin-dependent diabetes mellitus
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Role of glucose transporters i ...... in-dependent diabetes mellitus
@ast
Role of glucose transporters i ...... in-dependent diabetes mellitus
@en
type
label
Role of glucose transporters i ...... in-dependent diabetes mellitus
@ast
Role of glucose transporters i ...... in-dependent diabetes mellitus
@en
prefLabel
Role of glucose transporters i ...... in-dependent diabetes mellitus
@ast
Role of glucose transporters i ...... in-dependent diabetes mellitus
@en
P2093
P2860
P356
P1476
Role of glucose transporters i ...... in-dependent diabetes mellitus
@en
P2093
S Matthaei
T P Huecksteadt
W T Garvey
P2860
P304
P356
10.1172/JCI113485
P407
P577
1988-05-01T00:00:00Z