Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor.
about
TSH Receptor Signaling Abrogation by a Novel Small MoleculeStructural-Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at WorkNew small molecule agonists to the thyrotropin receptor.Mutations that silence constitutive signaling activity in the allosteric ligand-binding site of the thyrotropin receptor.Computational studies to predict or explain G protein coupled receptor polypharmacologyAllosteric model of maraviroc binding to CC chemokine receptor 5 (CCR5).Targeting the thyroid-stimulating hormone receptor with small molecule ligands and antibodiesDifferences in Signal Activation by LH and hCG are Mediated by the LH/CG Receptor's Extracellular Hinge RegionUpdate in TSH receptor agonists and antagonistsNovel insights on thyroid-stimulating hormone receptor signal transduction.Allosteric modulators hit the TSH receptor.Molecular sampling of the allosteric binding pocket of the TSH receptor provides discriminative pharmacophores for antagonist and agonistsGPCR-SSFE 2.0-a fragment-based molecular modeling web tool for Class A G-protein coupled receptors.From molecular details of the interplay between transmembrane helices of the thyrotropin receptor to general aspects of signal transduction in family a G-protein-coupled receptors (GPCRs).Structure and activation of the TSH receptor transmembrane domain.Expanding the Role of Thyroid-Stimulating Hormone in Skeletal Physiology.Differences between lutropin-mediated and choriogonadotropin-mediated receptor activation.
P2860
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P2860
Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Signaling-sensitive amino acid ...... e of the thyrotropin receptor.
@ast
Signaling-sensitive amino acid ...... e of the thyrotropin receptor.
@en
type
label
Signaling-sensitive amino acid ...... e of the thyrotropin receptor.
@ast
Signaling-sensitive amino acid ...... e of the thyrotropin receptor.
@en
prefLabel
Signaling-sensitive amino acid ...... e of the thyrotropin receptor.
@ast
Signaling-sensitive amino acid ...... e of the thyrotropin receptor.
@en
P2093
P2860
P356
P1433
P1476
Signaling-sensitive amino acid ...... e of the thyrotropin receptor.
@en
P2093
Ann-Karin Haas
Claudia Rutz
Gerd Krause
Gunnar Kleinau
Inna Hoyer
Jens Furkert
Marvin C Gershengorn
Ralf Schülein
Susanne Neumann
P2860
P304
P356
10.1096/FJ.09-149146
P407
P577
2010-02-23T00:00:00Z