Only high-affinity receptors for interleukin 2 mediate internalization of ligand.
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Transfer of in vivo primed transgenic T cells supports allergic lung inflammation and FIZZ1 and Ym1 production in an IL-4Rα and STAT6 dependent manner.Interleukin 2-diphtheria toxin fusion protein can abolish cell-mediated immunity in vivo.The internalization of nerve growth factor by high-affinity receptors on pheochromocytoma PC12 cells.TGN38 recycles basolaterally in polarized Madin-Darby canine kidney cellsContribution of a p75 interleukin 2 binding peptide to a high-affinity interleukin 2 receptor complexAnalysis of T cell subsets present in the peripheral blood and synovial fluid of reactive arthritis patientsRecombinant immunotoxins for the treatment of haematological malignancies.Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequenceADP-ribosylation factor 6 regulates a novel plasma membrane recycling pathway.Involvement of the ubiquitin/proteasome system in sorting of the interleukin 2 receptor beta chain to late endocytic compartmentsInternalization of interleukin 2 is mediated by the beta chain of the high-affinity interleukin 2 receptorInterleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor-mediated action of a diphtheria toxin-related interleukin 2 fusion proteinThe human interleukin 2 receptor beta chain (p70). Direct identification, partial purification, and patterns of expression on peripheral blood mononuclear cells.Essential role of the interleukin 2-interleukin 2 receptor pathway in thymocyte maturation in vivoInteractions between receptors for interleukin 2 and interleukin 4 on lines of helper T cells (HT-2) and B lymphoma cells (BCL1).Abnormal intracellular sorting of O-linked carbohydrate-deficient interleukin-2 receptors.Interleukin (IL)-2 and IL-3 induce distinct but overlapping responses in murine IL-3-dependent 32D cells transduced with human IL-2 receptor beta chain: involvement of tyrosine kinase(s) other than p56lck.Immunotoxins and cytokine toxin fusion proteins.Protein engineering of DAB-IL-2 fusion toxins to increase biologic potency.Recombinant immunotoxins containing truncated bacterial toxins for the treatment of hematologic malignanciesLongitudinal survey in an endemic region of plasma soluble interleukin-2 receptor and antibody levels in Plasmodium falciparum malaria.Nuclear Phosphoproteomic Screen Uncovers ACLY as Mediator of IL-2-induced Proliferation of CD4+ T lymphocytes.Availability of chemosensory receptors is down-regulated by habituation of larvae to a morphogenetic signal.Interleukin 2 mediates the inhibition of oligodendrocyte progenitor cell proliferation in vitro.Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex.An acidic sequence within the cytoplasmic domain of furin functions as a determinant of trans-Golgi network localization and internalization from the cell surface.Photoaffinity labeling of ATP and NAD+ binding sites on recombinant human interleukin 2.The multisubunit interleukin-2 receptor.An overview of the human interleukin-2 receptor: molecular, biochemical, and functional properties.Receptor-Mediated Transcytosis of Leptin through Human Intestinal Cells In Vitro.Association of p56lck with IL-2 receptor beta chain is critical for the IL-2-induced activation of p56lck.Distinct downstream signaling mechanism between erythropoietin receptor and interleukin-2 receptor.Intermolecular cystine-bonding of murine interleukin 2 indicates that ligand dimerization is important for the formation of the high-affinity receptor complex.Binding and internalization of interleukin 1 by T cells. Direct evidence for high- and low-affinity classes of interleukin 1 receptor.Co-internalization of the p55 and p70 subunits of the high-affinity human interleukin 2 receptor. Evidence for a stable ternary receptor complex.Contrasting interleukin 2 binding properties of the alpha (p55) and beta (p70) protein subunits of the human high-affinity interleukin 2 receptor.Transmembrane signaling of interleukin 2 receptor. Conformation and function of human interleukin 2 receptor (p55)/insulin receptor chimeric moleculesThe proteasome regulates receptor-mediated endocytosis of interleukin-2.Expression of functional human interleukin-2 receptors in murine interleukin-3-dependent cells.In vitro metabolic inhibition of the human lymphocyte: influence on the expression of interleukin-2 receptors.
P2860
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P2860
Only high-affinity receptors for interleukin 2 mediate internalization of ligand.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Only high-affinity receptors for interleukin 2 mediate internalization of ligand.
@ast
Only high-affinity receptors for interleukin 2 mediate internalization of ligand.
@en
type
label
Only high-affinity receptors for interleukin 2 mediate internalization of ligand.
@ast
Only high-affinity receptors for interleukin 2 mediate internalization of ligand.
@en
prefLabel
Only high-affinity receptors for interleukin 2 mediate internalization of ligand.
@ast
Only high-affinity receptors for interleukin 2 mediate internalization of ligand.
@en
P2093
P2860
P356
P1476
Only high-affinity receptors for interleukin 2 mediate internalization of ligand.
@en
P2093
Harford JB
Klausner RD
Leonard WL
Svetlik PB
Waldmann TA
Weissman AM
P2860
P304
P356
10.1073/PNAS.83.5.1463
P407
P577
1986-03-01T00:00:00Z