The N34S mutation of SPINK1 (PSTI) is associated with a familial pattern of idiopathic chronic pancreatitis but does not cause the disease.
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Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitisA novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK1 mutationsFramework for interpretation of trypsin-antitrypsin imbalance and genetic heterogeneity in pancreatitisGenetics of pancreatitisMolecular dynamics simulations reveal structural instability of human trypsin inhibitor upon D50E and Y54H mutations.Pathways to injury in chronic pancreatitis: decoding the role of the high-risk SPINK1 N34S haplotype using meta-analysis.Connections between genetics and clinical data: Role of MCP-1, CFTR, and SPINK-1 in the setting of acute, acute recurrent, and chronic pancreatitis.Expression of human cationic trypsinogen (PRSS1) in murine acinar cells promotes pancreatitis and apoptotic cell deathPRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitisReview of idiopathic pancreatitisRisk factors for pancreatic cancer: underlying mechanisms and potential targets.The prevalence of cationic trypsinogen (PRSS1) and serine protease inhibitor, Kazal type 1 (SPINK1) gene mutations in Polish patients with alcoholic and idiopathic chronic pancreatitisEvaluating Adults With Idiopathic Pancreatitis for Genetic Predisposition: Higher Prevalence of Abnormal Results With Use of Complete Gene Sequencing.Molecular characteristics of pancreatic ductal adenocarcinomaChronic pancreatitis and cystic fibrosis.The genetic predisposition and its impact on the diabetes mellitus development in patients with alcoholic chronic pancreatitis.Combined bicarbonate conductance-impairing variants in CFTR and SPINK1 variants are associated with chronic pancreatitis in patients without cystic fibrosis.Absence of PRSS1 mutations and association of SPINK1 trypsin inhibitor mutations in hereditary and non-hereditary chronic pancreatitis.Value of genetic testing in the management of pancreatitisComplete cystic fibrosis transmembrane conductance regulator gene sequencing in patients with idiopathic chronic pancreatitis and controls.Is Post-ERCP Pancreatitis a Genetically Predisposed Complication?Genetics of pancreatitis.Innovation and hard work: The 2015 George E. Palade Medal Award Lecture.Biochemistry and clinical role of trypsinogens and pancreatic secretory trypsin inhibitor.Gene-environment factors that contribute to alcoholic pancreatitis in humans.Genetic risk factors for pancreatic disorders.Role of genetic disorders in acute recurrent pancreatitis.SPINK1 is a susceptibility gene for fibrocalculous pancreatic diabetes in subjects from the Indian subcontinentSignal peptide variants that impair secretion of pancreatic secretory trypsin inhibitor (SPINK1) cause autosomal dominant hereditary pancreatitisEnvironmental risk factors for chronic pancreatitis and pancreatic cancer.Genetics of pancreatitis: an update for clinicians and genetic counselors.Involvement of inflammatory factors in pancreatic carcinogenesis and preventive effects of anti-inflammatory agents.Genetics of acute and chronic pancreatitis.Causal Evaluation of Acute Recurrent and Chronic Pancreatitis in Children: Consensus From the INSPPIRE Group.Missense mutations in pancreatic secretory trypsin inhibitor (SPINK1) cause intracellular retention and degradation.Anticipating disaster: the genetics of familial pancreatic cancer.Detection of oncogenes in chronic pancreatitis.Autoimmune pancreatitis--also a Western disease.The SPINK in chronic pancreatitis: similar finds, different minds.Genetic, epidemiological, and clinical aspects of hereditary pancreatitis: a population-based cohort study in Denmark.
P2860
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P2860
The N34S mutation of SPINK1 (PSTI) is associated with a familial pattern of idiopathic chronic pancreatitis but does not cause the disease.
description
2002 nî lūn-bûn
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
@zh-hk
2002年論文
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2002年論文
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2002年论文
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2002年论文
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2002年论文
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name
The N34S mutation of SPINK1 (P ...... ut does not cause the disease.
@ast
The N34S mutation of SPINK1 (P ...... ut does not cause the disease.
@en
type
label
The N34S mutation of SPINK1 (P ...... ut does not cause the disease.
@ast
The N34S mutation of SPINK1 (P ...... ut does not cause the disease.
@en
prefLabel
The N34S mutation of SPINK1 (P ...... ut does not cause the disease.
@ast
The N34S mutation of SPINK1 (P ...... ut does not cause the disease.
@en
P2093
P2860
P356
P1433
P1476
The N34S mutation of SPINK1 (P ...... ut does not cause the disease.
@en
P2093
A Andrén-Sandberg
D Whitcomb
J P Neoptolemos
J Threadgold
P2860
P304
P356
10.1136/GUT.50.5.675
P407
P577
2002-05-01T00:00:00Z