Translation of open reading frame E5 of bovine papillomavirus is required for its transforming activity.
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The BPV-1 E5 protein, the 16 kDa membrane pore-forming protein and the PDGF receptor exist in a complex that is dependent on hydrophobic transmembrane interactionsBovine papillomavirus E7 transformation function correlates with cellular p600 protein bindingPathobiology of papillomavirus-related cervical diseases: prospects for immunodiagnosis.Artificial transmembrane oncoproteins smaller than the bovine papillomavirus E5 protein redefine sequence requirements for activation of the platelet-derived growth factor beta receptor.Efficient transactivation and morphologic transformation by bovine papillomavirus genes expressed from a bovine papillomavirus/simian virus 40 recombinant virusPromoters and processing sites within the transforming region of bovine papillomavirus type 1Successive steps in the process of immortalization identified by transfer of separate bovine papillomavirus genes into rat fibroblasts.The E5 oncoprotein of bovine papillomavirus binds to a 16 kd cellular protein.Trans-activation of an upstream early gene promoter of bovine papilloma virus-1 by a product of the viral E2 gene.Differential promoter utilization by the bovine papillomavirus in transformed cells and productively infected wart tissuesGenetic and biochemical definition of the bovine papillomavirus E5 transforming protein.The bovine papillomavirus constitutive enhancer is essential for viral transformation, DNA replication, and the maintenance of latencyThe E5 proteinsHuman papillomavirus type 31 E5 protein supports cell cycle progression and activates late viral functions upon epithelial differentiation.Quantitative role of the human papillomavirus type 16 E5 gene during the productive stage of the viral life cycle.Multiple transmembrane amino acid requirements suggest a highly specific interaction between the bovine papillomavirus E5 oncoprotein and the platelet-derived growth factor beta receptor.Cellular transformation by a transmembrane peptide: structural requirements for the bovine papillomavirus E5 oncoprotein.Biologically active LIL proteins built with minimal chemical diversity.Negative regulation of the bovine papillomavirus E5, E6, and E7 oncogenes by the viral E1 and E2 genes.Mutational analysis of the interaction between the bovine papillomavirus E5 transforming protein and the endogenous beta receptor for platelet-derived growth factor in mouse C127 cells.Mutational analysis of the beta-type platelet-derived growth factor receptor defines the site of interaction with the bovine papillomavirus type 1 E5 transforming protein.E5 oncoprotein transmembrane mutants dissociate fibroblast transforming activity from 16-kilodalton protein binding and platelet-derived growth factor receptor binding and phosphorylation.Transforming properties of the cottontail rabbit papillomavirus oncoproteins Le6 and SE6 and of the E8 proteinMutational analysis of human papillomavirus type 11 E5a oncoproteinA papillomavirus E2 phosphorylation mutant exhibits normal transient replication and transcription but is defective in transformation and plasmid retentionBovine papillomavirus E7 oncoprotein inhibits anoikis.Analysis of HPV-1 E4 gene expression using epitope-defined antibodies.Bovine papillomavirus mutant temperature sensitive for transformation, replication and transactivation.Quantitative keratinocyte assay detects two biological activities of human papillomavirus DNA and identifies viral types associated with cervical carcinoma.Structurally related class I and class II receptor protein tyrosine kinases are down-regulated by the same E3 protein coded for by human group C adenovirusesModulation of cell function by small transmembrane proteins modeled on the bovine papillomavirus E5 protein.The v-sis protein retains biological activity as a type II membrane protein when anchored by various signal-anchor domains, including the hydrophobic domain of the bovine papilloma virus E5 oncoprotein.The bovine papillomavirus type 1 E5 transforming protein specifically binds and activates the beta-type receptor for the platelet-derived growth factor but not other related tyrosine kinase-containing receptors to induce cellular transformation.Specific interaction between the bovine papillomavirus E5 transforming protein and the beta receptor for platelet-derived growth factor in stably transformed and acutely transfected cellsMutation of the bovine papillomavirus E5 oncoprotein at amino acid 17 generates both high- and low-transforming variantsThe genomes of the animal papillomaviruses European elk papillomavirus, deer papillomavirus, and reindeer papillomavirus contain a novel transforming gene (E9) near the early polyadenylation site.The human papillomavirus type 6 and 16 E5 proteins are membrane-associated proteins which associate with the 16-kilodalton pore-forming protein.Importance of the bovine papillomavirus P2443 promoter in the regulation of E2 and E5 expression.Adenovirus E3 protein causes constitutively internalized epidermal growth factor receptors to accumulate in a prelysosomal compartment, resulting in enhanced degradationA glutamine residue in the membrane-associating domain of the bovine papillomavirus type 1 E5 oncoprotein mediates its binding to a transmembrane component of the vacuolar H(+)-ATPase.
P2860
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P2860
Translation of open reading frame E5 of bovine papillomavirus is required for its transforming activity.
description
1986 nî lūn-bûn
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1986年の論文
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1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
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1986年論文
@zh-tw
1986年论文
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1986年论文
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1986年论文
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name
Translation of open reading fr ...... for its transforming activity.
@ast
Translation of open reading fr ...... for its transforming activity.
@en
type
label
Translation of open reading fr ...... for its transforming activity.
@ast
Translation of open reading fr ...... for its transforming activity.
@en
prefLabel
Translation of open reading fr ...... for its transforming activity.
@ast
Translation of open reading fr ...... for its transforming activity.
@en
P2093
P2860
P356
P1476
Translation of open reading fr ...... for its transforming activity.
@en
P2093
D Guralski
J T Schiller
P2860
P304
P356
10.1073/PNAS.83.6.1797
P407
P577
1986-03-01T00:00:00Z