CFTR pharmacology and its role in intestinal fluid secretion.
about
Chloride channels as drug targets.GPR39 is coupled to TMEM16A in intestinal fibroblast-like cellsChloroquine stimulates Cl- secretion by Ca2+ activated Cl- channels in rat ileumZinc deficiency alters host response and pathogen virulence in a mouse model of enteroaggregative Escherichia coli-induced diarrhea.Monomeric CFTR in plasma membranes in live cells revealed by single molecule fluorescence imaging.Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy.On the mechanism of CFTR inhibition by a thiazolidinone derivative.Mutual enhancement of virulence by enterotoxigenic and enteropathogenic Escherichia coliBioactivity-guided fractionation of an antidiarrheal Chinese herb Rhodiola kirilowii (Regel) Maxim reveals (-)-epicatechin-3-gallate and (-)-epigallocatechin-3-gallate as inhibitors of cystic fibrosis transmembrane conductance regulator.Animal models of gastrointestinal and liver diseases. Animal models of cystic fibrosis: gastrointestinal, pancreatic, and hepatobiliary disease and pathophysiology.Stimulation of Airway and Intestinal Mucosal Secretion by Natural Coumarin CFTR ActivatorsFOXA2 regulates a network of genes involved in critical functions of human intestinal epithelial cells.A tannic acid-based medical food, Cesinex(®), exhibits broad-spectrum antidiarrheal properties: a mechanistic and clinical studyF508del-cystic fibrosis transmembrane regulator correctors for treatment of cystic fibrosis: a patent review.Escherichia coli in postweaning diarrhea in pigs: an update on bacterial types, pathogenesis, and prevention strategies.CFTR, chloride concentration and cell volume: could mammalian protein histidine phosphorylation play a latent role?Role of binding and nucleoside diphosphate kinase A in the regulation of the cystic fibrosis transmembrane conductance regulator by AMP-activated protein kinase.Antidiarrheal efficacy of a quinazolin CFTR inhibitor on human intestinal epithelial cell and in mouse model of choleraABSOLUTE CONFIGURATION AND BIOLOGICAL PROPERTIES OF ENANTIOMERS OF CFTR INHIBITOR BPO-27Pathogenesis of human enterovirulent bacteria: lessons from cultured, fully differentiated human colon cancer cell linesRethinking cholera pathogenesis- No longer all in the same "camp".Who's really in control: microbial regulation of protein trafficking in the epithelium.Glycosphingolipid functionsDeveloping novel antisecretory drugs to treat infectious diarrhea.Molecular motors and apical CFTR traffic in epithelia.Escherichia coli-induced epithelial hyporesponsiveness to secretagogues is associated with altered CFTR localization.Activation of CFTR trafficking and gating by vasoactive intestinal peptide in human bronchial epithelial cells.Inhibition of protein kinase CK2 closes the CFTR Cl channel, but has no effect on the cystic fibrosis mutant deltaF508-CFTR.Protein kinase CK2, cystic fibrosis transmembrane conductance regulator, and the deltaF508 mutation: F508 deletion disrupts a kinase-binding site.Potent, metabolically stable benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR inhibitors for polycystic kidney disease.Dehydrocostuslactone, a sesquiterpene lactone activates wild-type and ΔF508 mutant CFTR chloride channel.Involvement of phosphatidylinositol 3-kinase in cAMP- and cGMP-induced duodenal epithelial CFTR activation in mice.Effects of a small molecule R-spondin-1 substitute RS-246204 on a mouse intestinal organoid culture.Intestinal challenge with enterotoxigenic Escherichia coli in pigs, and nutritional intervention to prevent postweaning diarrhea.Parathyroid hormone (PTH) rapidly enhances CFTR-mediated HCO₃⁻ secretion in intestinal epithelium-like Caco-2 monolayer: a novel ion regulatory action of PTH
P2860
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P2860
CFTR pharmacology and its role in intestinal fluid secretion.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
CFTR pharmacology and its role in intestinal fluid secretion.
@ast
CFTR pharmacology and its role in intestinal fluid secretion.
@en
type
label
CFTR pharmacology and its role in intestinal fluid secretion.
@ast
CFTR pharmacology and its role in intestinal fluid secretion.
@en
prefLabel
CFTR pharmacology and its role in intestinal fluid secretion.
@ast
CFTR pharmacology and its role in intestinal fluid secretion.
@en
P1476
CFTR pharmacology and its role in intestinal fluid secretion.
@en
P2093
A S Verkman
Jay R Thiagarajah
P304
P356
10.1016/J.COPH.2003.06.012
P577
2003-12-01T00:00:00Z