A transgene insertion creating a heritable chromosome deletion mouse model of Prader-Willi and angelman syndromes
about
Deletion of the MBII-85 snoRNA gene cluster in mice results in postnatal growth retardationSnoRNA Snord116 (Pwcr1/MBII-85) deletion causes growth deficiency and hyperphagia in miceMaternal disruption of Ube3a leads to increased expression of Ube3a-ATS in trans.Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking dupliconsIdentification of novel imprinted transcripts in the Prader-Willi syndrome and Angelman syndrome deletion region: further evidence for regional imprinting controlAngelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypesStructure of the highly conserved HERC2 gene and of multiple partially duplicated paralogs in humanGenetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes.Prader-Willi and Angelman syndromes: sister imprinted disordersEpigenetic regulation of UBE3A and roles in human neurodevelopmental disorders.Insights into synaptic function from mouse models of human cognitive disorders.Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader-Willi syndrome.Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome.Necdin controls proliferation of white adipocyte progenitor cells.A neurodevelopmental survey of Angelman syndrome with genotype-phenotype correlations.Regulatory elements associated with paternally-expressed genes in the imprinted murine Angelman/Prader-Willi syndrome domain.A haplolethal locus uncovered by deletions in the mouse T complexGlobal deficits in development, function, and gene expression in the endocrine pancreas in a deletion mouse model of Prader-Willi syndrome.Distinct phenotypes distinguish the molecular classes of Angelman syndromeUnderstanding the pathogenesis of Angelman syndrome through animal modelsSpatial and temporal silencing of the human maternal UBE3A gene.A Drosophila model for Angelman syndrome.Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development.Differential gene expression reveals mitochondrial dysfunction in an imprinting center deletion mouse model of Prader-Willi syndromeZebrafish Models of Prader-Willi Syndrome: Fast Track to Pharmacotherapeutics.Natural breaking of the maternal silence at the mouse and human imprinted Prader-Willi locus: A whisper with functional consequences.Gene discovery and functional assessment of rare copy-number variants in neurodevelopmental disorders.Box C/D small nucleolar RNA genes and the Prader-Willi syndrome: a complex interplay.Recommendations for the investigation of animal models of Prader-Willi syndrome.The human MAGEL2 gene and its mouse homologue are paternally expressed and mapped to the Prader-Willi region.Whole genome microarray analysis of gene expression in an imprinting center deletion mouse model of Prader-Willi syndrome.
P2860
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P2860
A transgene insertion creating a heritable chromosome deletion mouse model of Prader-Willi and angelman syndromes
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
A transgene insertion creating ...... r-Willi and angelman syndromes
@ast
A transgene insertion creating ...... r-Willi and angelman syndromes
@en
type
label
A transgene insertion creating ...... r-Willi and angelman syndromes
@ast
A transgene insertion creating ...... r-Willi and angelman syndromes
@en
prefLabel
A transgene insertion creating ...... r-Willi and angelman syndromes
@ast
A transgene insertion creating ...... r-Willi and angelman syndromes
@en
P2093
P2860
P356
P1476
A transgene insertion creating ...... r-Willi and angelman syndromes
@en
P2093
J D Tucker
J M Gabriel
M J Ramsey
R D Nicholls
R G Caldwell
R Longnecker
P2860
P304
P356
10.1073/PNAS.96.16.9258
P407
P577
1999-08-01T00:00:00Z