Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro.
about
Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerasesStudies on the initiation and elongation reactions in the simian virus 40 DNA replication systemThe role of the 70 kDa subunit of human DNA polymerase alpha in DNA replicationRpa4, a homolog of the 34-kilodalton subunit of the replication protein A complexInteraction of DNA polymerase alpha-primase with cellular replication protein A and SV40 T antigenEffects of T antigen and replication protein A on the initiation of DNA synthesis by DNA polymerase alpha-primaseDNA polymerase II, the probable homolog of mammalian DNA polymerase epsilon, replicates chromosomal DNA in the yeast Saccharomyces cerevisiae.Replication factor A is required in vivo for DNA replication, repair, and recombinationThe B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication.Activation of SV40 DNA replication in vitro by cellular protein phosphatase 2AAssembly of simian virus 40 Okazaki pieces from DNA primers is reversibly arrested by ATP depletionThe cellular DNA polymerase alpha-primase is required for papillomavirus DNA replication and associates with the viral E1 helicaseInteractions of the papovavirus DNA replication initiator proteins, bovine papillomavirus type 1 E1 and simian virus 40 large T antigen, with human replication protein AProtein-protein interactions of the primase subunits p58 and p48 with simian virus 40 T antigen are required for efficient primer synthesis in a cell-free system.Amino acids 257 to 288 of mouse p48 control the cooperation of polyomavirus large T antigen, replication protein A, and DNA polymerase alpha-primase to synthesize DNA in vitro.The replication protein A binding site in simian virus 40 (SV40) T antigen and its role in the initial steps of SV40 DNA replication.The middle subunit of replication protein A contacts growing RNA-DNA primers in replicating simian virus 40 chromosomesCellular proteins required for adeno-associated virus DNA replication in the absence of adenovirus coinfection.Assembly of the replication initiation complex on SV40 origin DNA.Host-specific replication of BK virus DNA in mouse cell extracts is independently controlled by DNA polymerase alpha-primase and inhibitory activities.Multiple replication factors augment DNA synthesis by the two eukaryotic DNA polymerases, alpha and deltaViral E1 and E2 proteins support replication of homologous and heterologous papillomaviral originsFidelity of a human cell DNA replication complex.An inhibitor of the in vitro elongation reaction of simian virus 40 DNA replication is overcome by proliferating-cell nuclear antigen.Topoisomerase I associates specifically with simian virus 40 large-T-antigen double hexamer-origin complexesDifferent regions of primase subunit p48 control mouse polyomavirus and simian virus 40 DNA replication in vitro.Purification of replication protein C, a cellular protein involved in the initial stages of simian virus 40 DNA replication in vitro.Initiation of simian virus 40 DNA replication in vitro: pulse-chase experiments identify the first labeled species as topologically unwoundRole of single-stranded DNA binding activity of T antigen in simian virus 40 DNA replicationLinks between replication, recombination and genome instability in eukaryotesReconstitution of simian virus 40 DNA replication with purified proteins.The origin of bidirectional DNA replication in polyoma virus.Nonspecific DNA binding activity of simian virus 40 large T antigen: evidence for the cooperation of two regions for full activity.Natural biology of polyomavirus middle T antigen.Studies on the DNA elongation inhibitor and its proliferating cell nuclear antigen-dependent control in simian virus 40 DNA replication in vitro.Synthesis of DNA containing the simian virus 40 origin of replication by the combined action of DNA polymerases alpha and delta.Requirement for two DNA polymerases in the replication of simian virus 40 DNA in vitro.Multiple functions of human single-stranded-DNA binding protein in simian virus 40 DNA replication: single-strand stabilization and stimulation of DNA polymerases alpha and delta.Simian virus 40 large tumor antigen requires three core replication origin domains for DNA unwinding and replication in vitroSimian virus 40 (SV40) DNA replication: SV40 large T antigen unwinds DNA containing the SV40 origin of replication.
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P2860
Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro.
@ast
Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro.
@en
type
label
Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro.
@ast
Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro.
@en
prefLabel
Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro.
@ast
Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro.
@en
P2093
P2860
P356
P1476
Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro.
@en
P2093
P2860
P304
P356
10.1073/PNAS.83.9.2869
P407
P577
1986-05-01T00:00:00Z