Interferon alpha as a primary pathogenic factor in human lupus
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Dysregulation of antiviral helicase pathways in systemic lupus erythematosusNucleic Acid sensors and type I interferon production in systemic lupus erythematosusThe autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunityMDA5-positive dermatomyositis: an uncommon entity in Europe with variable clinical presentationsAdvances in lupus geneticsIRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosusEmerging therapies for systemic lupus erythematosus--focus on targeting interferon-alphaBrief Report: IRF5 systemic lupus erythematosus risk haplotype is associated with asymptomatic serologic autoimmunity and progression to clinical autoimmunity in mothers of children with neonatal lupusThe dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunityThe pathogenesis of systemic lupus erythematosus—an updateOsteopontin alleles are associated with clinical characteristics in systemic lupus erythematosus.Pivotal Functions of Plasmacytoid Dendritic Cells in Systemic Autoimmune Pathogenesis.Genetic-epigenetic dysregulation of thymic TSH receptor gene expression triggers thyroid autoimmunityCopy Number Variation of TLR-7 Gene and its Association with the Development of Systemic Lupus Erythematosus in Female Patients from Yucatan Mexico.The effect of the autoimmunity-associated gene, PTPN22, on a BXSB-derived model of lupusEvidence of dynamically dysregulated gene expression pathways in hyperresponsive B cells from African American lupus patients.Interferon regulatory factors: critical mediators of human lupus.Interferons in autoimmune and inflammatory diseases: regulation and roles.Widely divergent transcriptional patterns between SLE patients of different ancestral backgrounds in sorted immune cell populationsMyeloid dendritic cells from B6.NZM Sle1/Sle2/Sle3 lupus-prone mice express an IFN signature that precedes disease onsetLarge-scale analysis of tumor necrosis factor α levels in systemic lupus erythematosusInterferon-inducible Ifi200-family genes as modifiers of lupus susceptibility.Tolerogenic versus inflammatory activity of peripheral blood monocytes and dendritic cells subpopulations in systemic lupus erythematosus.Gene-expression-guided selection of candidate loci and molecular phenotype analyses enhance genetic discovery in systemic lupus erythematosus.The genetics of human autoimmune disease: A perspective on progress in the field and future directions.Immunogenetics of systemic lupus erythematosus: A comprehensive review.Monogenic forms of systemic lupus erythematosus: new insights into SLE pathogenesisDesign, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9.Exacerbated autoimmunity in the absence of TLR9 in MRL.Fas(lpr) mice depends on Ifnar1Population pharmacokinetic analysis of sifalimumab from a clinical phase IIb trial in systemic lupus erythematosus patientsMechanistic biomarkers for clinical decision making in rheumatic diseases.Expression of murine Unc93b1 is up-regulated by interferon and estrogen signaling: implications for sex bias in the development of autoimmunity.Activation of the Interferon Pathway is Dependent Upon Autoantibodies in African-American SLE Patients, but Not in European-American SLE Patients.Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients.Familial aggregation of high tumor necrosis factor alpha levels in systemic lupus erythematosus.Scavenging nucleic acid debris to combat autoimmunity and infectious disease.Genetic variation near IRF8 is associated with serologic and cytokine profiles in systemic lupus erythematosus and multiple sclerosis.Fueling autoimmunity: type I interferon in autoimmune diseases.Genetics of the type I interferon pathway in systemic lupus erythematosus.Functional genetic polymorphisms in ILT3 are associated with decreased surface expression on dendritic cells and increased serum cytokines in lupus patients
P2860
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P2860
Interferon alpha as a primary pathogenic factor in human lupus
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Interferon alpha as a primary pathogenic factor in human lupus
@ast
Interferon alpha as a primary pathogenic factor in human lupus
@en
type
label
Interferon alpha as a primary pathogenic factor in human lupus
@ast
Interferon alpha as a primary pathogenic factor in human lupus
@en
prefLabel
Interferon alpha as a primary pathogenic factor in human lupus
@ast
Interferon alpha as a primary pathogenic factor in human lupus
@en
P2860
P356
P1476
Interferon alpha as a primary pathogenic factor in human lupus
@en
P2860
P304
P356
10.1089/JIR.2011.0071
P577
2011-09-16T00:00:00Z