Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients.
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Lupus Nephritis: A Different Disease in European Patients?Establishing an analytic pipeline for genome-wide DNA methylationEpigenetic Modulation as a Therapeutic Prospect for Treatment of Autoimmune Rheumatic DiseasesCD3Z hypermethylation is associated with severe clinical manifestations in systemic lupus erythematosus and reduces CD3ζ-chain expression in T cells.Genome-wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjögren's syndrome.Decreased mRNA expression levels of DNA methyltransferases type 1 and 3A in systemic lupus erythematosus.DNA methylation modulates HRES1/p28 expression in B cells from patients with Lupus.Metabolic control of the epigenome in systemic Lupus erythematosus.Hepatic expression profiles in retroviral infection: relevance to drug hypersensitivity risk.Type I interferon in the pathogenesis of lupus.Accounting for population stratification in DNA methylation studies.Epigenome-wide scan identifies a treatment-responsive pattern of altered DNA methylation among cytoskeletal remodeling genes in monocytes and CD4+ T cells from patients with Behçet's disease.Advances in lupus genetics and epigeneticsGenome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies.Transcriptional and epigenetic regulation of T-helper lineage specification.The DNA methylation signature of human TCRαβ+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune responseEpigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils.T cells as a therapeutic target in SLE.Bone marrow stromal antigen 2 (BST-2) DNA is demethylated in breast tumors and breast cancer cells.Genetics of juvenile idiopathic arthritis: new tools bring new approaches.Whole genome methylation array reveals the down-regulation of IGFBP6 and SATB2 by HIV-1.Genome-Wide Assessment of Differential DNA Methylation Associated with Autoantibody Production in Systemic Lupus Erythematosus.The real culprit in systemic lupus erythematosus: abnormal epigenetic regulation.DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosisRenal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells.The Upregulation of Genomic Imprinted DLK1-Dio3 miRNAs in Murine Lupus Is Associated with Global DNA Hypomethylation.DNA methylation patterns in naïve CD4+ T cells identify epigenetic susceptibility loci for malar rash and discoid rash in systemic lupus erythematosus.DNA methylation at IL32 in juvenile idiopathic arthritis.eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data.Immunogenetics of systemic lupus erythematosus: A comprehensive review.Genome-Wide DNA Methylation Analysis of Chinese Patients with Systemic Lupus Erythematosus Identified Hypomethylation in Genes Related to the Type I Interferon Pathway.Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve?Ethnicity-specific epigenetic variation in naïve CD4+ T cells and the susceptibility to autoimmunity.Epigenetics in systemic lupus erythematosusOverlap between differentially methylated DNA regions in blood B lymphocytes and genetic at-risk loci in primary Sjögren's syndromeMonocyte enhancers are highly altered in systemic lupus erythematosus.Epigenetic Aspects of Systemic Lupus Erythematosus.Whole-genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic lupus erythematosus.Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes.Genome-wide profiling identifies associations between lupus nephritis and differential methylation of genes regulating tissue hypoxia and type 1 interferon responses.
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Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 April 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Genome-wide DNA methylation st ...... + T cells from lupus patients.
@en
Genome-wide DNA methylation st ...... + T cells from lupus patients.
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type
label
Genome-wide DNA methylation st ...... + T cells from lupus patients.
@en
Genome-wide DNA methylation st ...... + T cells from lupus patients.
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Genome-wide DNA methylation st ...... + T cells from lupus patients.
@en
Genome-wide DNA methylation st ...... + T cells from lupus patients.
@nl
P2093
P2860
P1476
Genome-wide DNA methylation st ...... + T cells from lupus patients.
@en
P2093
Amr H Sawalha
Joan T Merrill
Jonathan D Wren
Kristi A Koelsch
Nezam Altorok
Patrick Coit
W Joseph McCune
P2860
P356
10.1016/J.JAUT.2013.04.003
P577
2013-04-24T00:00:00Z