Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography.
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Synthesis, structure-affinity relationships, and radiolabeling of selective high-affinity 5-HT4 receptor ligands as prospective imaging probes for positron emission tomographyUntangling tau imagingInsight into the Molecular Imaging of Alzheimer's DiseaseClinicopathologic assessment and imaging of tauopathies in neurodegenerative dementiasModeling of PET data in CNS drug discovery and development.PET radiotracers: crossing the blood-brain barrier and surviving metabolismStriatal and extrastriatal dopamine release measured with PET and [(18)F] fallyprideDose-occupancy study of striatal and extrastriatal dopamine D2 receptors by aripiprazole in schizophrenia with PET and [18F]fallypride.Exploring the impact of BDNF Val66Met genotype on serotonin transporter and serotonin-1A receptor bindingDesign, synthesis, radiolabeling, and in vivo evaluation of carbon-11 labeled N-[2-[4-(3-cyanopyridin-2-yl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a potential positron emission tomography tracer for the dopamine D(4) receptorsDiscovery and labeling of high-affinity 3,4-diarylpyrazolines as candidate radioligands for in vivo imaging of cannabinoid subtype-1 (CB1) receptors.Avoiding barriers to PET radioligand development: cellular assays of brain efflux transportersSynthesis and evaluation of translocator 18 kDa protein (TSPO) positron emission tomography (PET) radioligands with low binding sensitivity to human single nucleotide polymorphism rs6971.An Improved Antagonist Radiotracer for the κ-Opioid Receptor: Synthesis and Characterization of (11)C-LY2459989.Development of N-methyl-(2-arylquinolin-4-yl)oxypropanamides as leads to PET radioligands for translocator protein (18 kDa).Tau PET imaging: present and future directions.Synthesis and evaluation of radioligands for imaging brain nociceptin/orphanin FQ peptide (NOP) receptors with positron emission tomographyN-(4-cyanotetrahydro-2H-pyran-4-yl) and N-(1-cyanocyclohexyl) derivatives of 1,5-diarylpyrazole-3-carboxamides showing high affinity for 18 kDa translocator protein and/or cannabinoid receptorsEx Vivo Characterization of a Novel Iodine-123-Labelled Aminomethylchroman as a Potential Agonist Ligand for SPECT Imaging of Dopamine D2/3 Receptors.New N-aryl-N'-(3-(substituted)phenyl)-N'-methylguanidines as leads to potential PET radioligands for imaging the open NMDA receptor.Evaluation in monkey of two candidate PET radioligands, [(11) C]RX-1 and [(18) F]RX-2, for imaging brain 5-HT4 receptorsPET tracers for serotonin receptors and their applicationsEvaluation of novel N1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands.Development of SPECT imaging agents for the norepinephrine transporters: [123I]INERRadiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofuran chemotype.Quantification of dopamine transporter density with [18F]FECNT PET in healthy humans[carbonyl-11C]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([11C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate receptor 1 (mGluR1) in monkey brain.A hybrid deconvolution approach for estimation of in vivo non-displaceable binding for brain PET targets without a reference regionLigand electronic properties modulate tau filament binding site densityThe role of emission tomography in pharmacokinetic and pharmacodynamic studies in clinical psychopharmacology.Radiosynthesis and evaluation of [¹¹C-carbonyl]-labeled carbamates as fatty acid amide hydrolase radiotracers for positron emission tomography.Kinetics modeling and occupancy studies of a novel C-11 PET tracer for VAChT in nonhuman primates.Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. Nicotinic ligands of enhanced subtype selectivity.Synthesis, ex vivo evaluation, and radiolabeling of potent 1,5-diphenylpyrrolidin-2-one cannabinoid subtype-1 receptor ligands as candidates for in vivo imaging.Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET.Synthesis of 5- and 6-substituted 2-(4-dimethylaminophenyl)-1,3-benzoxazoles and their in vitro and in vivo evaluation as imaging agents for amyloid plaque.N'-3-(Trifluoromethyl)phenyl Derivatives of N-Aryl-N'-methylguanidines as Prospective PET Radioligands for the Open Channel of the N-Methyl-d-aspartate (NMDA) Receptor: Synthesis and Structure-Affinity RelationshipsSynthesis and evaluation of 11C-LY2795050 as a κ-opioid receptor antagonist radiotracer for PET imagingOn quantitative relationships between drug-like compound lipophilicity and plasma free fraction in monkey and human.Synthesis and evaluation in monkey of [(18)F]4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([(18)F]FIMX): a promising radioligand for PET imaging of brain metabotropic glutamate receptor 1 (mGluR1)
P2860
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P2860
Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Relationships between radiotra ...... positron emission tomography.
@ast
Relationships between radiotra ...... positron emission tomography.
@en
type
label
Relationships between radiotra ...... positron emission tomography.
@ast
Relationships between radiotra ...... positron emission tomography.
@en
prefLabel
Relationships between radiotra ...... positron emission tomography.
@ast
Relationships between radiotra ...... positron emission tomography.
@en
P2093
P1476
Relationships between radiotra ...... positron emission tomography.
@en
P2093
Marc Laruelle
Mark Slifstein
Yiyun Huang
P304
P356
10.1016/J.MIBIO.2003.09.009
P577
2003-11-01T00:00:00Z