The c-Met Tyrosine Kinase Inhibitor JNJ-38877605 Causes Renal Toxicity through Species-Specific Insoluble Metabolite Formation
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Mass Spectrometry Imaging of Drug Related Crystal-Like Structures in Formalin-Fixed Frozen and Paraffin-Embedded Rabbit Kidney Tissue SectionsMcl-1 downregulation leads to the heightened sensitivity exhibited by BCR-ABL positive ALL to induction of energy and ER-stress.Preclinical and clinical evaluation of MET functions in cancer cells and in the tumor stroma.Prevalence of Non-Cytochrome P450-Mediated Metabolism in Food and Drug Administration-Approved Oral and Intravenous Drugs: 2006-2015.Evaluating the Disposition of a Mixed Aldehyde Oxidase/Cytochrome P450 Substrate in Rats with Attenuated P450 Activity.The Potential of Minipigs in the Development of Anticancer Therapeutics: Species Comparison and Examples of Special Applications.ecoAO: A Simple System for the Study of Human Aldehyde Oxidases Role in Drug Metabolism.Cytochrome P450 and Non-Cytochrome P450 Oxidative Metabolism: Contributions to the Pharmacokinetics, Safety, and Efficacy of Xenobiotics.Simultaneous quantification of volitinib and gefitinib in rat plasma by HPLC-MS/MS for application to a pharmacokinetic study in rats.
P2860
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P2860
The c-Met Tyrosine Kinase Inhibitor JNJ-38877605 Causes Renal Toxicity through Species-Specific Insoluble Metabolite Formation
description
2015 nî lūn-bûn
@nan
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
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2015年论文
@zh-cn
name
The c-Met Tyrosine Kinase Inhi ...... Insoluble Metabolite Formation
@ast
The c-Met Tyrosine Kinase Inhi ...... Insoluble Metabolite Formation
@en
type
label
The c-Met Tyrosine Kinase Inhi ...... Insoluble Metabolite Formation
@ast
The c-Met Tyrosine Kinase Inhi ...... Insoluble Metabolite Formation
@en
prefLabel
The c-Met Tyrosine Kinase Inhi ...... Insoluble Metabolite Formation
@ast
The c-Met Tyrosine Kinase Inhi ...... Insoluble Metabolite Formation
@en
P2093
P2860
P1476
The c-Met Tyrosine Kinase Inhi ...... Insoluble Metabolite Formation
@en
P2093
Erio Barale
Ferry A L M Eskens
Hendrik-Tobias Arkenau
Hilde H Bohets
Johann S de Bono
Leni van Doorn
Maja J A de Jonge
Martijn P Lolkema
Peter Hellemans
P2860
P304
P356
10.1158/1078-0432.CCR-14-3258
P407
P577
2015-03-05T00:00:00Z