Attenuation of phagocytosis of xenogeneic cells by manipulating CD47.
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CD47: A Cell Surface Glycoprotein Which Regulates Multiple Functions of Hematopoietic Cells in Health and DiseaseLack of CD47 on nonhematopoietic cells induces split macrophage tolerance to CD47null cellsClinical pig liver xenotransplantation: how far do we have to go?Innate cellular immunity and xenotransplantation.Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages.Analysis of innate defences against Plasmodium falciparum in immunodeficient mice.Mouse models with human immunity and their application in biomedical research.Expression of recipient CD47 on rat insulinoma cell xenografts prevents macrophage-mediated rejection through SIRPα inhibitory signaling in mice.Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.High incidence of xenogenic bone marrow engraftment in pig-to-baboon intra-bone bone marrow transplantationMacrophages prevent human red blood cell reconstitution in immunodeficient mice."Velcro" engineering of high affinity CD47 ectodomain as signal regulatory protein α (SIRPα) antagonists that enhance antibody-dependent cellular phagocytosisFull reconstitution of human platelets in humanized mice after macrophage depletion.Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts.Current progress in xenogeneic tolerance.CD47 is required for suppression of allograft rejection by donor-specific transfusion.CD47: a new target in cardiovascular therapy.Immune tolerance: mechanisms and application in clinical transplantation.Persistence of Indirect but Not Direct T Cell Xenoresponses in Baboon Recipients of Pig Cell and Organ Transplants.Rapid dendritic cell activation and resistance to allotolerance induction in anti-CD154-treated mice receiving CD47-deficient donor-specific transfusionHigh antigen levels do not preclude B-cell tolerance induction to alpha1,3-Gal via mixed chimerism.Manipulating the immune system for anti-tumor responses and transplant tolerance via mixed hematopoietic chimerism.Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells.Achieving tolerance in pig-to-primate xenotransplantation: reality or fantasy.Immune responses following mouse peripheral nerve xenotransplantation in ratsCD47 in xenograft rejection and tolerance induction.CD47: a new player in phagocytosis and xenograft rejection.Human lymphohematopoietic reconstitution and immune function in immunodeficient mice receiving cotransplantation of human thymic tissue and CD34(+) cells.T-cell-mediated immunological barriers to xenotransplantationITIM-dependent negative signaling pathways for the control of cell-mediated xenogeneic immune responses.Xenotransplantation: immunological hurdles and progress toward tolerance.Longer storage of red blood cells is associated with increased in vitro erythrophagocytosis.Comparative Analysis of Immune Checkpoint Molecules and Their Potential Role in the Transmissible Tasmanian Devil Facial Tumor Disease.Survival and function of CD47-deficient thymic grafts in mice.Human CD47 expression permits survival of porcine cells in immunodeficient mice that express SIRPα capable of binding to human CD47Innate immunity and resistance to tolerogenesis in allotransplantationRole of CD47 and Signal Regulatory Protein Alpha (SIRPα) in Regulating the Clearance of Viable or Aged Blood Cells.Lack of CD47 on donor hepatocytes promotes innate immune cell activation and graft loss: a potential barrier to hepatocyte xenotransplantation.Transgenic expression of human CD47 markedly increases engraftment in a murine model of pig-to-human hematopoietic cell transplantation.Gene expression patterns in livers of Hispanic patients infected with hepatitis C virus.
P2860
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P2860
Attenuation of phagocytosis of xenogeneic cells by manipulating CD47.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Attenuation of phagocytosis of xenogeneic cells by manipulating CD47.
@ast
Attenuation of phagocytosis of xenogeneic cells by manipulating CD47.
@en
type
label
Attenuation of phagocytosis of xenogeneic cells by manipulating CD47.
@ast
Attenuation of phagocytosis of xenogeneic cells by manipulating CD47.
@en
prefLabel
Attenuation of phagocytosis of xenogeneic cells by manipulating CD47.
@ast
Attenuation of phagocytosis of xenogeneic cells by manipulating CD47.
@en
P2093
P2860
P1433
P1476
Attenuation of phagocytosis of xenogeneic cells by manipulating CD47.
@en
P2093
Jon VerHalen
Maria Lucia Madariaga
Megan Sykes
Per-Arne Oldenborg
Shuanglin Xiang
Shumei Wang
P2860
P304
P356
10.1182/BLOOD-2006-04-019794
P407
P577
2006-09-28T00:00:00Z