Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist.
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Model Organisms in G Protein-Coupled Receptor ResearchAdhesion G Protein-Coupled Receptors: From In Vitro Pharmacology to In Vivo MechanismsOrphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function.Epithelial Gpr116 regulates pulmonary alveolar homeostasis via Gq/11 signaling.Dihydromunduletone Is a Small-Molecule Selective Adhesion G Protein-Coupled Receptor AntagonistStalk-dependent and Stalk-independent Signaling by the Adhesion G Protein-coupled Receptors GPR56 (ADGRG1) and BAI1 (ADGRB1)Super-complexes of adhesion GPCRs and neural guidance receptors.Gpr126/Adgrg6 Has Schwann Cell Autonomous and Nonautonomous Functions in Peripheral Nerve Injury and Repair.Disease-associated extracellular loop mutations in the adhesion G protein-coupled receptor G1 (ADGRG1; GPR56) differentially regulate downstream signaling.Activation of Adhesion GPCR EMR2/ADGRE2 Induces Macrophage Differentiation and Inflammatory Responses via Gα16/Akt/MAPK/NF-κB Signaling PathwaysTethered Agonism: A Common Activation Mechanism of Adhesion GPCRs.Classification, Nomenclature, and Structural Aspects of Adhesion GPCRs.G Protein-Coupled Receptors in Myelinating Glia.Introduction: History of the Adhesion GPCR Field.7TM Domain Structure of Adhesion GPCRs.Understanding the Structural Basis of Adhesion GPCR Functions.Control of Adhesion GPCR Function Through Proteolytic Processing.Versatile Signaling Activity of Adhesion GPCRs.Adhesion GPCRs as a Putative Class of Metabotropic Mechanosensors.Adhesion GPCRs Govern Polarity of Epithelia and Cell Migration.Adhesion GPCRs as Novel Actors in Neural and Glial Cell Functions: From Synaptogenesis to Myelination.Adhesion G-protein coupled receptors and extracellular matrix proteins: Roles in myelination and glial cell development.Opportunities for therapeutic antibodies directed at G-protein-coupled receptors.Metalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity.Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains.Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons.Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4).Stachel-independent modulation of GPR56/ADGRG1 signaling by synthetic ligands directed to its extracellular region.Analysis of myelinated axon formation in zebrafish.Activation of Adhesion G Protein-coupled Receptors: AGONIST SPECIFICITY OF STACHEL SEQUENCE-DERIVED PEPTIDES.Ciliary Mechanisms of Cyst Formation in Polycystic Kidney Disease.GPCR Retreat 2014: a good view leads to many discoveries!Membrane-association of EMR2/ADGRE2-NTF is regulated by site-specific N-glycosylation.Gedunin- and Khivorin-Derivatives Are Small-Molecule Partial Agonists for Adhesion G Protein-Coupled Receptors GPR56/ADGRG1 and GPR114/ADGRG5.Cancer Cell Mechanics: Adhesion G Protein-coupled Receptors in Action?The Activation and Signaling Mechanisms of GPR56/ADGRG1 in Melanoma Cell
P2860
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P2860
Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Adhesion G protein-coupled rec ...... of a cryptic tethered agonist.
@ast
Adhesion G protein-coupled rec ...... of a cryptic tethered agonist.
@en
type
label
Adhesion G protein-coupled rec ...... of a cryptic tethered agonist.
@ast
Adhesion G protein-coupled rec ...... of a cryptic tethered agonist.
@en
prefLabel
Adhesion G protein-coupled rec ...... of a cryptic tethered agonist.
@ast
Adhesion G protein-coupled rec ...... of a cryptic tethered agonist.
@en
P2093
P2860
P356
P1476
Adhesion G protein-coupled rec ...... of a cryptic tethered agonist.
@en
P2093
Alexander G Hajduczok
Gregory G Tall
Hannah M Stoveken
P2860
P304
P356
10.1073/PNAS.1421785112
P407
P577
2015-04-27T00:00:00Z