Pharmacologic induction of CD8+ T cell memory: better living through chemistry
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Targeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor ImmunitySorting through subsets: which T-cell populations mediate highly effective adoptive immunotherapy?GSK-3 as potential target for therapeutic intervention in cancerExploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinicThe Impact of Chemotherapy, Radiation and Epigenetic Modifiers in Cancer Cell Expression of Immune Inhibitory and Stimulatory Molecules and Anti-Tumor EfficacyA human memory T cell subset with stem cell-like propertiesMultifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapyHuman effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy.A non-human primate model for analysis of safety, persistence, and function of adoptively transferred T cells.Immune modulation effects of concomitant temozolomide and radiation therapy on peripheral blood mononuclear cells in patients with glioblastoma multiforme.Therapeutic cancer vaccines: are we there yet?Reprogramming antitumor immunityRepression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells.New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancerDistinct effects of saracatinib on memory CD8+ T cell differentiation.Wnt/beta-catenin signaling in T-cell immunity and cancer immunotherapy.Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways.Unraveling graft-versus-host disease and graft-versus-leukemia responses using TCR Vβ spectratype analysis in a murine bone marrow transplantation model.T cells expanded in presence of IL-15 exhibit increased antioxidant capacity and innate effector molecules.Wnt signaling inhibits CTL memory programming.Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function.A cytokine cocktail directly modulates the phenotype of DC-enriched anti-tumor T cells to convey potent anti-tumor activities in a murine model.Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy.Role of PI3K/Akt signaling in memory CD8 T cell differentiation.Rapamycin-resistant effector T-cell therapy.Aptamer-Targeted Attenuation of IL-2 Signaling in CD8+ T Cells Enhances Antitumor Immunity.T memory stem cells in health and disease.Emerging concepts of T cell metabolism as a target of immunotherapy.Modulating the differentiation status of ex vivo-cultured anti-tumor T cells using cytokine cocktails.4-1BB signaling activates glucose and fatty acid metabolism to enhance CD8+ T cell proliferation.
P2860
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P2860
Pharmacologic induction of CD8+ T cell memory: better living through chemistry
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Pharmacologic induction of CD8+ T cell memory: better living through chemistry
@ast
Pharmacologic induction of CD8+ T cell memory: better living through chemistry
@en
type
label
Pharmacologic induction of CD8+ T cell memory: better living through chemistry
@ast
Pharmacologic induction of CD8+ T cell memory: better living through chemistry
@en
prefLabel
Pharmacologic induction of CD8+ T cell memory: better living through chemistry
@ast
Pharmacologic induction of CD8+ T cell memory: better living through chemistry
@en
P2860
P1476
Pharmacologic induction of CD8+ T cell memory: better living through chemistry
@en
P2093
Luca Gattinoni
P2860
P304
P356
10.1126/SCITRANSLMED.3000302
P407
P577
2009-12-01T00:00:00Z