Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy.
about
Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure.2-Hydroxyoleic acid induces ER stress and autophagy in various human glioma cell linesRe-configuration of sphingolipid metabolism by oncogenic transformation.Interdiction of sphingolipid metabolism to improve standard cancer therapies.A high-throughput screen identifies miRNA inhibitors regulating lung cancer cell survival and response to paclitaxel.Inhibition of Phosphatidylcholine-Specific Phospholipase C Interferes with Proliferation and Survival of Tumor Initiating Cells in Squamous Cell CarcinomaNon-small cell lung cancer is characterized by dramatic changes in phospholipid profiles.2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy.Repurposing Cationic Amphiphilic Antihistamines for Cancer TreatmentLipidomic Signatures and Associated Transcriptomic Profiles of Clear Cell Renal Cell CarcinomaRegulation of membrane KCNQ1/KCNE1 channel density by sphingomyelin synthase 1.Optimized Protocol To Analyze Changes in the Lipidome of Xenografts after Treatment with 2-Hydroxyoleic Acid.Lipidomic Profiling of Lung Pleural Effusion Identifies Unique Metabotype for EGFR Mutants in Non-Small Cell Lung Cancer2'-Hydroxy ceramide in membrane homeostasis and cell signaling.Phospholipids of tumor extracellular vesicles stratify gefitinib-resistant nonsmall cell lung cancer cells from gefitinib-sensitive cellsSphingolipids: key regulators of apoptosis and pivotal players in cancer drug resistanceMolecular dynamics simulations of heterogeneous cell membranes in response to uniaxial membrane stretches at high loading ratesThe unfolded protein response in the therapeutic effect of hydroxy-DHA against Alzheimer's disease.The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport.Sustained activation of sphingomyelin synthase by 2-hydroxyoleic acid induces sphingolipidosis in tumor cells.Anti-proliferative effects of tricyclodecan-9-yl-xanthogenate (D609) involve ceramide and cell cycle inhibitionThe tricyclodecan-9-yl-xanthogenate D609 triggers ceramide increase and enhances FasL-induced caspase-dependent and -independent cell death in T lymphocytesSphingomyelin metabolism is involved in the differentiation of MDCK cells induced by environmental hypertonicity.Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells.The use of alternative polyadenylation in the tissue-specific regulation of human SMS1 gene expression.Cognitive recovery and restoration of cell proliferation in the dentate gyrus in the 5XFAD transgenic mice model of Alzheimer's disease following 2-hydroxy-DHA treatment.Sphingolipid metabolism in cancer signalling and therapy.2-Hydroxyoleic acid-inserted liposomes as a multifunctional carrier of anticancer drugs.Bcr-Abl regulation of sphingomyelin synthase 1 reveals a novel oncogenic-driven mechanism of protein up-regulation.
P2860
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P2860
Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Sphingomyelin and sphingomyeli ...... n 2-hydroxyoleic acid therapy.
@ast
Sphingomyelin and sphingomyeli ...... n 2-hydroxyoleic acid therapy.
@en
type
label
Sphingomyelin and sphingomyeli ...... n 2-hydroxyoleic acid therapy.
@ast
Sphingomyelin and sphingomyeli ...... n 2-hydroxyoleic acid therapy.
@en
prefLabel
Sphingomyelin and sphingomyeli ...... n 2-hydroxyoleic acid therapy.
@ast
Sphingomyelin and sphingomyeli ...... n 2-hydroxyoleic acid therapy.
@en
P2093
P2860
P50
P356
P1476
Sphingomyelin and sphingomyeli ...... in 2-hydroxyoleic acid therapy
@en
P2093
Amaia Marcilla-Etxenike
Burhard Kleuser
Francisca Guardiola-Serrano
John E Halver
Maria Antònia Noguera-Salvà
P2860
P304
19569-19574
P356
10.1073/PNAS.1115484108
P407
P577
2011-11-21T00:00:00Z