Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases
about
Mechanisms for initiating cellular DNA replicationLoading and activation of DNA replicative helicases: the key step of initiation of DNA replicationA role for H2B ubiquitylation in DNA replicationIn the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.Helicase loading at chromosomal origins of replicationStructural and mechanistic insights into Mcm2-7 double-hexamer assembly and functionA unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNAMCM Paradox: Abundance of Eukaryotic Replicative Helicases and Genomic Integrity.Cdc6-induced conformational changes in ORC bound to origin DNA revealed by cryo-electron microscopyJuvenile Hormone Activates the Transcription of Cell-division-cycle 6 (Cdc6) for Polyploidy-dependent Insect Vitellogenesis and OogenesisCharacterization of conserved arginine residues on Cdt1 that affect licensing activity and interaction with Geminin or Mcm complex.Diverged composition and regulation of the Trypanosoma brucei origin recognition complex that mediates DNA replication initiationChromosome Duplication in Saccharomyces cerevisiae.The origin recognition complex: a biochemical and structural view.A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formationSwitch on the engine: how the eukaryotic replicative helicase MCM2-7 becomes activated.Mechanisms and regulation of DNA replication initiation in eukaryotes.Dynamic association of ORCA with prereplicative complex components regulates DNA replication initiation.Building a double hexamer of DNA helicase at eukaryotic replication originsATPase-dependent quality control of DNA replication origin licensing.Cdt1 stabilizes an open MCM ring for helicase loading.Single-molecule studies of origin licensing reveal mechanisms ensuring bidirectional helicase loading.The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formationThe ORC/Cdc6/MCM2–7 complex, a new power player for regulated helicase loadingOpen-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer.Conservation and Variation in Strategies for DNA Replication of Kinetoplastid Nuclear Genomes.Prereplication-complex formation: a molecular double take?
P2860
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P2860
Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases
@ast
Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases
@en
type
label
Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases
@ast
Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases
@en
prefLabel
Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases
@ast
Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases
@en
P2860
P356
P1433
P1476
Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases
@en
P2093
Stephen P Bell
Thomas J Takara
P2860
P304
P356
10.1038/EMBOJ.2011.394
P407
P577
2011-11-01T00:00:00Z