Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells.
about
Cadmium Protection Strategies--A Hidden Trade-Off?Redox balance dynamically regulates vascular growth and remodelingCadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signalingCadmium induces histone H3 lysine methylation by inhibiting histone demethylase activityA review of molecular events of cadmium-induced carcinogenesisComputer-aided targeting of the PI3K/Akt/mTOR pathway: toxicity reduction and therapeutic opportunitiesAlteration in Mir-21/PTEN expression modulates gefitinib resistance in non-small cell lung cancerActivation of protease-activated receptor 2 induces VEGF independently of HIF-1.Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brainMiR-101 and miR-144 regulate the expression of the CFTR chloride channel in the lungRuta graveolens L. induces death of glioblastoma cells and neural progenitors, but not of neurons, via ERK 1/2 and AKT activation.Inhibition of beta-catenin signaling by Pb leads to incomplete fracture healingHypoxia and free radicals: role in tumor progression and the use of engineering-based platforms to address these relationships.Cadmium and proliferation in human uterine leiomyoma cells: evidence of a role for EGFR/MAPK pathways but not classical estrogen receptor pathwaysProteomic analysis of secreted proteins by human bronchial epithelial cells in response to cadmium toxicity.VEGFA Expression Is Inhibited by Arsenic Trioxide in HUVECs through the Upregulation of Ets-2 and miRNA-126.Requirement of ERα and basal activities of EGFR and Src kinase in Cd-induced activation of MAPK/ERK pathway in human breast cancer MCF-7 cells.Cadmium Activates Multiple Signaling Pathways That Coordinately Stimulate Akt Activity to Enhance c-Myc mRNA Stability.Molecular Mechanisms of Malignant Transformation by Low Dose Cadmium in Normal Human Bronchial Epithelial Cells.Cadmium promotes the proliferation of triple-negative breast cancer cells through EGFR-mediated cell cycle regulation.2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated production of reactive oxygen species is an essential step in the mechanism of action to accelerate human keratinocyte differentiation.Hypoxia-response element (HRE)-directed transcriptional regulation of the rat lysyl oxidase gene in response to cobalt and cadmium.Silibinin inhibits VEGF secretion and age-related macular degeneration in a hypoxia-dependent manner through the PI-3 kinase/Akt/mTOR pathway.Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells.MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers.Seven in absentia homolog 2 (Siah2) protein is a regulator of NF-E2-related factor 2 (Nrf2)ETS2 and Twist1 promote invasiveness of Helicobacter pylori-infected gastric cancer cells by inducing Siah2Stanniocalcin-1 Protects a Mouse Model from Renal Ischemia-Reperfusion Injury by Affecting ROS-Mediated Multiple Signaling PathwaysErianin inhibits high glucose-induced retinal angiogenesis via blocking ERK1/2-regulated HIF-1α-VEGF/VEGFR2 signaling pathwayChronic cadmium exposure in vitro induces cancer cell characteristics in human lung cells.Chemotherapy agents-induced immunoresistance in lung cancer cells could be reversed by trop-2 inhibition in vitro and in vivo by interaction with MAPK signaling pathway.Dual oxidase 2 and pancreatic adenocarcinoma: IFN-γ-mediated dual oxidase 2 overexpression results in H2O2-induced, ERK-associated up-regulation of HIF-1α and VEGF-A.A common response to common danger? Comparison of animal and plant signaling pathways involved in cadmium sensing.Cadmium and cellular signaling cascades: interactions between cell death and survival pathways.NADPH oxidase 5 (NOX5)-induced reactive oxygen signaling modulates normoxic HIF-1α and p27Kip1 expression in malignant melanoma and other human tumors.Low-dose cadmium exposure induces peribronchiolar fibrosis through site-specific phosphorylation of vimentin.Low-Dose Cadmium Upregulates VEGF Expression in Lung Adenocarcinoma Cells.Probable Chemical Hypoxia Effects on Progress of CNV Through Induction of Promoter CpG Demethylation and Overexpression of IL17RC in Human RPE Cells.BNIP3 upregulation by ERK and JNK mediates cadmium-induced necrosis in neuronal cells.Cadmium selectively induces MIP-2 and COX-2 through PTEN-mediated Akt activation in RAW264.7 cells.
P2860
Q26775119-E37724F0-DACC-469A-863F-F3A5888EFEFAQ27004547-F57CE934-8C6D-49AE-AD74-6749AD57C2A2Q28389261-CC3DADDE-ED8B-4155-B519-4E0F33BED396Q28392271-113B7510-FE2E-4141-A20D-E2AC9BDEC33EQ28395274-90FC1BE2-A11A-4D64-A1E5-5F0FF1001882Q28397537-D4D7417C-9B8B-4134-85D3-AEBB314B20CAQ28541175-161B0FBA-2BB9-4742-B94E-A2D91FA63770Q31103929-25F0689E-9CD4-43BA-AF97-2712CA5798A2Q33694968-C645B0E2-05BB-49F0-BBD8-A6FA59C8E551Q34505995-BFF93DF3-32A0-4A3F-8661-070475D5E298Q34668694-C482B749-0B6F-4626-A980-047B002D6824Q35041009-4C07C946-0E0D-45E5-897D-EF67CCEDC89DQ35117865-F20DDB1B-1054-4504-9319-04A082D7EB3DQ35256471-283247EF-ACC6-43AB-9B9E-E228293E958CQ35624241-DC6D3B5E-392E-44E4-8DBD-ECFD42CC961AQ35746000-75240B9C-0838-4853-AF51-54BF0A4B531BQ35815562-844AAED1-3AEC-49C5-81A5-2A5CF9CCD0F3Q35889906-8715BA8C-071F-4FBC-8304-204210B6DD8FQ36019689-CA552D81-D73B-4954-996E-21258B01CD7AQ36236932-ED9CA0F7-609E-478A-A125-973C886E25B1Q36620467-E423A4F0-17B5-4956-BCB1-818894871064Q36678475-E13EB926-8180-4B1C-A32C-7E8419F71AFEQ36781055-1099CED9-661A-4C98-9D60-82B73F487436Q36905866-6512313E-4D0F-441A-83E0-CC80DE84C04AQ36906199-013BB9E2-85A5-44B8-A39F-A8C3A94804F4Q36947840-13E91C0B-B009-4E2F-8016-6E303B868789Q36955086-80136E0A-738D-4D37-8B74-D7CDA911AA8CQ37134433-D6BF226A-06EF-4E52-AF0A-18FEA2ABDB03Q37291255-DAD6A91A-B963-4D09-A426-5F8B849BB572Q37393770-F1790713-8F7D-4A39-BE67-110A31D60724Q37548848-A0A346DB-FC93-4094-A80E-C865FE7389CBQ37684358-2719FBC2-51F8-477A-9545-5ABD86925E52Q38032227-5C5828D2-42BE-4C32-A7FA-043F793CA359Q38132083-D62708FE-9F64-4CC3-A3C8-3BFA06EC910FQ38696004-B431CB1F-EF97-414D-B2F2-DE579023C816Q38816027-AF464D7A-56BE-4137-B7E0-50E261C108EEQ38837495-8A26F910-3123-4A78-A4D1-CD9C99241D9EQ38924650-44A699FD-C8C5-41D4-95BA-ECACC33085D2Q38995351-3DFDE382-C4A8-4E80-B291-257DDCC2A41BQ39032050-E23656A3-BEC8-417A-A5A0-7103341FD9BB
P2860
Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Cadmium increases HIF-1 and VE ...... an bronchial epithelial cells.
@ast
Cadmium increases HIF-1 and VE ...... an bronchial epithelial cells.
@en
type
label
Cadmium increases HIF-1 and VE ...... an bronchial epithelial cells.
@ast
Cadmium increases HIF-1 and VE ...... an bronchial epithelial cells.
@en
prefLabel
Cadmium increases HIF-1 and VE ...... an bronchial epithelial cells.
@ast
Cadmium increases HIF-1 and VE ...... an bronchial epithelial cells.
@en
P2093
P2860
P50
P356
P1476
Cadmium increases HIF-1 and VE ...... an bronchial epithelial cells.
@en
P2093
Faton Agani
John Barnett
Nancy Lan Guo
Yingxue Zhu
P2860
P356
10.1093/TOXSCI/KFR256
P577
2011-10-09T00:00:00Z