Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals - Wikidata - awgldk - TriplyDB

Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals

Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals

http://www.wikidata.org/entity/Q35626858

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Role of methylglyoxal in Alzheimer's disease Edaravone protects against methylglyoxal-induced barrier damage in human brain endothelial cells Neuropathology of type 2 diabetes: a short review on insulin-related mechanisms Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans Dietary Sugars and Endogenous Formation of Advanced Glycation Endproducts: Emerging Mechanisms of Disease.On the Relationship between Energy Metabolism, Proteostasis, Aging and Parkinson's Disease: Possible Causative Role of Methylglyoxal and Alleviative Potential of Carnosine.Dietary advanced glycation end products are associated with decline in memory in young elderly.Methylglyoxal, the dark side of glycolysis GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.High dietary advanced glycation end products are associated with poorer spatial learning and accelerated Aβ deposition in an Alzheimer mouse model.Managing chronic inflammation in the aging diabetic patient with CKD by diet or sevelamer carbonate: a modern paradigm shift.Suppression of native defense mechanisms, SIRT1 and PPARγ, by dietary glycoxidants precedes disease in adult humans; relevance to lifestyle-engendered chronic diseases.Methylglyoxal (MG) and cerebro-renal interaction: does long-term orally administered MG cause cognitive impairment in normal Sprague-Dawley rats?Nutrition and AGE-ing: Focusing on Alzheimer's Disease.Subcutaneous liraglutide ameliorates methylglyoxal-induced Alzheimer-like tau pathology and cognitive impairment by modulating tau hyperphosphorylation and glycogen synthase kinase-3β Cognitive function in idiopathic intracranial hypertension: a prospective case-control study The role of methylglyoxal and the glyoxalase system in diabetes and other age-related diseases.Common neurodegenerative pathways in obesity, diabetes, and Alzheimer's disease.Methylglyoxal-induced AMPK activation leads to autophagic degradation of thioredoxin 1 and glyoxalase 2 in HT22 nerve cells.Methylglyoxal in Metabolic Disorders: Facts, Myths, and Promises.Dicarbonyls and Advanced Glycation End-Products in the Development of Diabetic Complications and Targets for Intervention.Suppression of methylglyoxal hyperactivity by mangiferin can prevent diabetes-associated cognitive decline in rats.Evaluation of Polyphenol Anthocyanin-Enriched Extracts of Blackberry, Black Raspberry, Blueberry, Cranberry, Red Raspberry, and Strawberry for Free Radical Scavenging, Reactive Carbonyl Species Trapping, Anti-Glycation, Anti-β-Amyloid Aggregation, a Methylglyoxal-induced cytotoxicity in neonatal rat brain: a role for oxidative stress and MAP kinases.Methylglyoxal Disrupts Paranodal Axoglial Junctions via Calpain Activation.Activation of Macrophages and Microglia by Interferon-γ and Lipopolysaccharide Increases Methylglyoxal Production: A New Mechanism in the Development of Vascular Complications and Cognitive Decline in Type 2 Diabetes Mellitus?

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Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals

http://www.wikidata.org/entity/Q35626858

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J.MAD.2011.10.007

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Mechanisms of Ageing and Development

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Serum concentration of an infl ...... decline in elderly individuals

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Erin Moshier

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Helen Vlassara

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Hillel T Grossman

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Jaime Uribarri

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James Godbold

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James Schmeidler

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Jeremy M Silverman

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Mary Sano

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Michal Schnaider Beeri

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Sarah Reddy

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P2860

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

Glyoxalase I--structure, function and a critical role in the enzymatic defence against glycation

Prediction of creatinine clearance from serum creatinine

Glyoxalase I – structure, function and a critical role in the enzymatic defence against glycation

Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress

Education delays accelerated decline on a memory test in persons who develop dementia.

Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy

Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I.

Life expectancy and changing mortality.

Age, gender, and education norms on the CERAD neuropsychological battery in the oldest old.

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10.1016/J.MAD.2011.10.007

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11-12

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132

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