Overexpression of the D-alanine racemase gene confers resistance to D-cycloserine in Mycobacterium smegmatis.
about
Pediatric fecal microbiota harbor diverse and novel antibiotic resistance genesCrystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase.A balancing act: efflux/influx in mycobacterial drug resistanceResistance to antibiotics targeted to the bacterial cell wallStructure of the Mycobacterium tuberculosis D-Alanine:D-Alanine Ligase, a Target of the Antituberculosis Drug D-CycloserineStructure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzymeKinetic mechanism and inhibition of Mycobacterium tuberculosis D-alanine:D-alanine ligase by the antibiotic D-cycloserineA point mutation in cycA partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis BCG vaccine strainsExposure to antibiotics induces expression of the Mycobacterium tuberculosis sigF gene: implications for chemotherapy against mycobacterial persistorsWhole genome sequencing reveals complex evolution patterns of multidrug-resistant Mycobacterium tuberculosis Beijing strains in patientsSelection and characterization of conditionally active promoters in Lactobacillus plantarum, using alanine racemase as a promoter probe.New Insights in to the Intrinsic and Acquired Drug Resistance Mechanisms in MycobacteriaDetection of kanamycin-resistant Mycobacterium tuberculosis by identifying mutations in the 16S rRNA gene.Characterization of a Mycobacterium smegmatis mutant that is simultaneously resistant to D-cycloserine and vancomycinUse of the alr gene as a food-grade selection marker in lactic acid bacteriaExtensively Drug-Resistant Tuberculosis: A Sign of the Times and an Impetus for Antimicrobial Discovery.Depletion of antibiotic targets has widely varying effects on growthGenetic Approaches to Facilitate Antibacterial Drug Development.QSAR based therapeutic management of M. tuberculosis.Genomic characterization and assessment of the virulence and antibiotic resistance of the novel species Paenibacillus sp. strain VT-400, a potentially pathogenic bacterium in the oral cavity of patients with hematological malignanciesGenomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance.Drug-Resistant Tuberculosis: Challenges and Progress.Mycobacterium tuberculosis: drug resistance and future perspectives.Metabolomics analysis identifies d-Alanine-d-Alanine ligase as the primary lethal target of d-Cycloserine in mycobacteriaViable screening targets related to the bacterial cell wall.Molecular basis underlying Mycobacterium tuberculosis D-cycloserine resistance. Is there a role for ubiquinone and menaquinone metabolic pathways?PipY, a Member of the Conserved COG0325 Family of PLP-Binding Proteins, Expands the Cyanobacterial Nitrogen Regulatory Network.Drug Resistance Mechanisms in Mycobacterium tuberculosis.Glutamate Racemase Is the Primary Target of β-Chloro-d-Alanine in Mycobacterium tuberculosis.Mycobacterium smegmatis D-Alanine Racemase Mutants Are Not Dependent on D-Alanine for Growth.Roles of Mycobacterium smegmatis D-alanine:D-alanine ligase and D-alanine racemase in the mechanisms of action of and resistance to the peptidoglycan inhibitor D-cycloserine.Characterization of Escherichia coli D-cycloserine transport and resistant mutants.High-Level Heterologous Production of D-Cycloserine by Escherichia coli.Identification of novel mutations associated with cycloserine resistance in Mycobacterium tuberculosis.Use of NMR metabolomics to analyze the targets of D-cycloserine in mycobacteria: role of D-alanine racemase.Proline racemases: insights into Trypanosoma cruzi peptides containing D-proline.Self-protection mechanism in D-cycloserine-producing Streptomyces lavendulae. Gene cloning, characterization, and kinetics of its alanine racemase and D-alanyl-D-alanine ligase, which are target enzymes of D-cycloserine.Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine.Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions.
P2860
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P2860
Overexpression of the D-alanine racemase gene confers resistance to D-cycloserine in Mycobacterium smegmatis.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Overexpression of the D-alanin ...... ne in Mycobacterium smegmatis.
@ast
Overexpression of the D-alanin ...... ne in Mycobacterium smegmatis.
@en
type
label
Overexpression of the D-alanin ...... ne in Mycobacterium smegmatis.
@ast
Overexpression of the D-alanin ...... ne in Mycobacterium smegmatis.
@en
prefLabel
Overexpression of the D-alanin ...... ne in Mycobacterium smegmatis.
@ast
Overexpression of the D-alanin ...... ne in Mycobacterium smegmatis.
@en
P2093
P2860
P1476
Overexpression of the D-alanin ...... ne in Mycobacterium smegmatis.
@en
P2093
P2860
P304
P356
10.1128/JB.179.16.5046-5055.1997
P407
P577
1997-08-01T00:00:00Z