TET family proteins and their role in stem cell differentiation and transformation.
about
Overexpression of Cancer-Associated Genes via Epigenetic Derepression Mechanisms in Gynecologic CancerAssociation of global DNA methylation and global DNA hydroxymethylation with metals and other exposures in human blood DNA samplesAcute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identityMechanisms and functions of Tet protein-mediated 5-methylcytosine oxidationCytosine modifications in neurodevelopment and diseasesMechanisms of epigenetic regulation of leukemia onset and progressionMyeloid malignancies: mutations, models and managementProperties and biological roles of TET proteins during embryogenesis and in hematopoiesisGenome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's diseaseBase-resolution profiling of active DNA demethylation using MAB-seq and caMAB-seqMyeloid neoplasias: what molecular analyses are telling usTET enzymes, TDG and the dynamics of DNA demethylation.The curious origins of angioimmunoblastic T-cell lymphomaMetabolic requirements for the maintenance of self-renewing stem cells.Evaluation of allelic strength of human TET2 mutations and cooperation between Tet2 knockdown and oncogenic Nras mutation.Cancer genetics and epigenetics: two sides of the same coin?Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanomaMicroRNA-15b promotes neurogenesis and inhibits neural progenitor proliferation by directly repressing TET3 during early neocortical development.5-azacytidine improves the osteogenic differentiation potential of aged human adipose-derived mesenchymal stem cells by DNA demethylationVitamin C facilitates dopamine neuron differentiation in fetal midbrain through TET1- and JMJD3-dependent epigenetic control mannerHydroxymethylation of DNA: an epigenetic marker.TET1 is controlled by pluripotency-associated factors in ESCs and downmodulated by PRC2 in differentiated cells and tissuesCancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex.Genetic Determinants of Epigenetic Patterns: Providing Insight into Disease.TET proteins and 5-methylcytosine oxidation in hematological cancersTET1 Depletion Induces Aberrant CpG Methylation in Colorectal Cancer Cells.Acute loss of TET function results in aggressive myeloid cancer in mice.Molecular basis of targeted therapy in T/NK-cell lymphoma/leukemia: A comprehensive genomic and immunohistochemical analysis of a panel of 33 cell linesTissue of origin determines cancer-associated CpG island promoter hypermethylation patternsTargeting epigenetic regulations in cancerTET family proteins: oxidation activity, interacting molecules, and functions in diseases.Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungiThe Impact of DNA Methylation in Hematopoietic Malignancies.miR-506 inhibits cell proliferation and invasion by targeting TET family in colorectal cancer.Transgenerational latent early-life associated regulation unites environment and genetics across generationsDecreased 5-Hydroxymethylcytosine (5-hmC) predicts poor prognosis in early-stage laryngeal squamous cell carcinoma.TET1 knockdown inhibits the odontogenic differentiation potential of human dental pulp cells.Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease.MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling.Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells.
P2860
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P2860
TET family proteins and their role in stem cell differentiation and transformation.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
TET family proteins and their role in stem cell differentiation and transformation.
@ast
TET family proteins and their role in stem cell differentiation and transformation.
@en
type
label
TET family proteins and their role in stem cell differentiation and transformation.
@ast
TET family proteins and their role in stem cell differentiation and transformation.
@en
prefLabel
TET family proteins and their role in stem cell differentiation and transformation.
@ast
TET family proteins and their role in stem cell differentiation and transformation.
@en
P2093
P2860
P1433
P1476
TET family proteins and their role in stem cell differentiation and transformation
@en
P2093
Iannis Aifantis
Luisa Cimmino
Ross L Levine
P2860
P304
P356
10.1016/J.STEM.2011.08.007
P407
P577
2011-09-01T00:00:00Z