Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy
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Gene therapy in clinical medicineOriginal Nerve Growth Factor Mimetic Dipeptide GK-2 Restores Impaired Cognitive Functions in Rat Models of Alzheimer's DiseaseLocal and remote growth factor effects after primate spinal cord injury.Differential effects of intrastriatal 6-hydroxydopamine on cell number and morphology in midbrain dopaminergic subregions of the ratDissecting the effect of aging on the neural substrates of memory: deterioration, preservation or functional reorganization?Neuroregeneration in neurodegenerative disorders.Human gene therapy and imaging in neurological diseases.Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic miceEstrogen therapy and cognition: a review of the cholinergic hypothesisFailed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion.Oestrogen and nerve growth factor - neuroprotection and repair in Alzheimer's disease.Nontropic actions of neurotrophins: subcortical nerve growth factor gene delivery reverses age-related degeneration of primate cortical cholinergic innervation.Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice.Evaluation of a combined therapeutic regimen of 8-OH-DPAT and environmental enrichment after experimental traumatic brain injury.GPR30 co-localizes with cholinergic neurons in the basal forebrain and enhances potassium-stimulated acetylcholine release in the hippocampus.Normal genetic variation, cognition, and aging.The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer disease.GPR30 is positioned to mediate estrogen effects on basal forebrain cholinergic neurons and cognitive performance.Regional protein levels of cytosolic phospholipase A2 and cyclooxygenase-2 in Rhesus monkey brain as a function of ageDonepezil plus estradiol treatment enhances learning and delay-dependent memory performance by young ovariectomized rats with partial loss of septal cholinergic neuronsCholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model.Biologic and plastic effects of experimental traumatic brain injury treatment paradigms and their relevance to clinical rehabilitation.Neurotrophins and neurodegeneration.Lessons from the analysis of nonhuman primates for understanding human aging and neurodegenerative diseasesGene therapy for neurological disease.Galanthamine plus estradiol treatment enhances cognitive performance in aged ovariectomized rats.Reactivation of atrophic neurons in Alzheimer's disease.Gene Therapy Models of Alzheimer's Disease and Other Dementias.Current advances in using neurotrophic factors to treat neurodegenerative disordersPositive allosteric modulator of α7 nicotinic-acetylcholine receptors, PNU-120596 augments the effects of donepezil on learning and memory in aged rodents and non-human primates.Neurotrophic factors in neurodegeneration.Cytoskeletal transport in the aging brain: focus on the cholinergic system.Specific mechanism for blood inflow stimulation in brain area prone to Alzheimer's disease lesions.Long-term reversal of cholinergic neuronal decline in aged non-human primates by lentiviral NGF gene deliveryA comparison of model-based (2D) and design-based (3D) stereological methods for estimating cell number in the substantia nigra pars compacta (SNpc) of the C57BL/6J mouseGene therapy in Alzheimer's disease - potential for disease modificationEffects of two years of conjugated equine estrogens on cholinergic neurons in young and middle-aged ovariectomized monkeysTherapy of neurodegenerative diseases using neurotrophic factors: cell biological perspective.Effects of fibroblast transplantation into the internal pallidum on levodopa-induced dyskinesias in parkinsonian non-human primates.Non human primate models for Alzheimer's disease-related research and drug discovery.
P2860
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P2860
Age-associated neuronal atrophy occurs in the primate brain and is reversible by growth factor gene therapy
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Age-associated neuronal atroph ...... by growth factor gene therapy
@ast
Age-associated neuronal atroph ...... by growth factor gene therapy
@en
type
label
Age-associated neuronal atroph ...... by growth factor gene therapy
@ast
Age-associated neuronal atroph ...... by growth factor gene therapy
@en
prefLabel
Age-associated neuronal atroph ...... by growth factor gene therapy
@ast
Age-associated neuronal atroph ...... by growth factor gene therapy
@en
P2093
P2860
P356
P1476
Age-associated neuronal atroph ...... by growth factor gene therapy
@en
P2093
M H Tuszynski
P2860
P304
10893-10898
P356
10.1073/PNAS.96.19.10893
P407
P577
1999-09-01T00:00:00Z