Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells. - Wikidata - awgldk - TriplyDB

Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells.

Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells.

http://www.wikidata.org/entity/Q35638571

about

Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy Radiotherapy combination opportunities leveraging immunity for the next oncology practice Cord Blood as a Source of Natural Killer Cells Trial Watch: Adoptive cell transfer for oncological indications Identification of the genomic insertion site of Pmel-1 TCR α and β transgenes by next-generation sequencing Thrombotic microangiopathy in metastatic melanoma patients treated with adoptive cell therapy and total body irradiation.Heat shock protein vaccination and directed IL-2 therapy amplify tumor immunity rapidly following bone marrow transplantation in mice.Autologous tumor lysate-pulsed dendritic cell immunotherapy for pediatric patients with newly diagnosed or recurrent high-grade gliomas.The allure and peril of hematopoietic stem cell transplantation: overcoming immune challenges to improve success.IFN-γ upregulates survivin and Ifi202 expression to induce survival and proliferation of tumor-specific T cells.Successful remission rates and survival after lymphodepleting chemotherapy and donor lymphocyte infusion for relapsed hematologic malignancies postallogeneic hematopoietic cell transplantation.Nanoscale artificial antigen presenting cells for T cell immunotherapy Oncogene withdrawal engages the immune system to induce sustained cancer regression.The future is now: chimeric antigen receptors as new targeted therapies for childhood cancer Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer.Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor.Immunological treatment options for locoregionally advanced head and neck squamous cell carcinoma CD8+ enriched "young" tumor infiltrating lymphocytes can mediate regression of metastatic melanoma.An essential role for the immune system in the mechanism of tumor regression following targeted oncogene inactivation.Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy.SLC45A2: A Melanoma Antigen with High Tumor Selectivity and Reduced Potential for Autoimmune Toxicity.Genetically engineered T cells for the treatment of cancer.Therapeutic cancer vaccines: are we there yet?CD4+ T cells inhibit the neu-specific CD8+ T-cell exhaustion during the priming phase of immune responses against breast cancer Irradiation enhances human T-cell function by upregulating CD70 expression on antigen-presenting cells in vitro.miR-155 augments CD8+ T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γc cytokines.Adoptive cell therapy for patients with melanoma.Adoptive T cell immunotherapy for cancer.Generation of CAR T cells for adoptive therapy in the context of glioblastoma standard of care.Mouse model for pre-clinical study of human cancer immunotherapy.Synergy of brief activation of CD8 T-cells in the presence of IL-12 and adoptive transfer into lymphopenic hosts promotes tumor clearance and anti-tumor memory.Determinants of successful CD8+ T-cell adoptive immunotherapy for large established tumors in mice.Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice Novel role of hematopoietic stem cells in immunologic rejection of malignant gliomas.Dendritic Cells in Irradiated Mice Trigger the Functional Plasticity and Antitumor Activity of Adoptively Transferred Tc17 Cells via IL12 Signaling In Vitro and In Vivo Antitumor Effect of Anti-CD33 Chimeric Receptor-Expressing EBV-CTL against CD33 Acute Myeloid Leukemia Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma Trial Watch: Adoptive cell transfer immunotherapy.Levels of peripheral CD4(+)FoxP3(+) regulatory T cells are negatively associated with clinical response to adoptive immunotherapy of human cancer.

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P2860

Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells.

http://www.wikidata.org/entity/Q35638571

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Increased intensity lymphodepl ...... ferred tumor-specific T cells.

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Increased intensity lymphodepl ...... ferred tumor-specific T cells.

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type

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Increased intensity lymphodepl ...... ferred tumor-specific T cells.

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Increased intensity lymphodepl ...... ferred tumor-specific T cells.

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Increased intensity lymphodepl ...... ferred tumor-specific T cells.

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Journal of Immunotherapy

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Increased intensity lymphodepl ...... ferred tumor-specific T cells.

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Andrew Kaiser

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Chrystal M Paulos

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Claudia Wrzesinski

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Luca Gattinoni

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Nicholas P Restifo

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Pawel Muranski

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Steven A Rosenberg

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Zhiya Yu

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P2860

Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

Adoptive immunotherapy for cancer: building on success

Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

Natural selection of tumor variants in the generation of "tumor escape" phenotypes

IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

Tumor-specific Th17-polarized cells eradicate large established melanoma

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19952961

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