The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity.
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A fluorescently tagged C-terminal fragment of p47phox detects NADPH oxidase dynamics during phagocytosis.Vav family exchange factors: an integrated regulatory and functional viewFc gamma R-stimulated activation of the NADPH oxidase: phosphoinositide-binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome.Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells.Redox modifier genes and pathways in amyotrophic lateral sclerosis.Topological and functional properties of the small GTPases protein interaction network.Systemic lupus erythematosus-associated neutrophil cytosolic factor 2 mutation affects the structure of NADPH oxidase complexPhospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2.Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase.Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COS(phox) cells.Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in miceAn ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells.Identification of the catalytic site of phospholipase D2 (PLD2) newly described guanine nucleotide exchange factor activityUpon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin.Reduced neutrophil chemotaxis and infiltration contributes to delayed resolution of cutaneous wound infection with advanced age.Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats.Expression of RAC2 in endothelial cells is required for the postnatal neovascular response.Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations.The basic biology of redoxosomes in cytokine-mediated signal transduction and implications for disease-specific therapies.Activation of the neutrophil NADPH oxidase by Aspergillus fumigatus.p120-catenin in canonical Wnt signaling.Beneficial effects of edaravone, a novel antioxidant, in rats with dilated cardiomyopathy.Structure analysis between the SWAP-70 RHO-GEF and the newly described PLD2-GEFThe antioxidant edaravone attenuates ER-stress-mediated cardiac apoptosis and dysfunction in rats with autoimmune myocarditis.Multiple increased osteoclast functions in individuals with neurofibromatosis type 1.Mulberry leaf diet protects against progression of experimental autoimmune myocarditis to dilated cardiomyopathy via modulation of oxidative stress and MAPK-mediated apoptosis.Biomaterials differentially regulate Src kinases and phosphoinositide 3-kinase-γ in polymorphonuclear leukocyte primary and tertiary granule release.
P2860
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P2860
The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The Rac effector p67phox regul ...... nucleotide exchange activity.
@ast
The Rac effector p67phox regul ...... nucleotide exchange activity.
@en
type
label
The Rac effector p67phox regul ...... nucleotide exchange activity.
@ast
The Rac effector p67phox regul ...... nucleotide exchange activity.
@en
prefLabel
The Rac effector p67phox regul ...... nucleotide exchange activity.
@ast
The Rac effector p67phox regul ...... nucleotide exchange activity.
@en
P2093
P2860
P356
P1476
The Rac effector p67phox regul ...... nucleotide exchange activity.
@en
P2093
Daniel D Billadeau
Lawrence A Quilliam
Mary C Dinauer
Wenyu Ming
P2860
P304
P356
10.1128/MCB.00985-06
P407
P577
2006-10-23T00:00:00Z