The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex
about
Prevention of DNA re-replication in eukaryotic cellsDDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrestGenomic instability in cancer.A novel mutation in β integrin reveals an integrin-mediated interaction between the extracellular matrix and cki-1/p27KIP1Cycle inhibiting factors (cifs): cyclomodulins that usurp the ubiquitin-dependent degradation pathway of host cells.Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosisUbiquitin E3 ligase CRL4(CDT2/DCAF2) as a potential chemotherapeutic target for ovarian surface epithelial cancerInvasive Cell Fate Requires G1 Cell-Cycle Arrest and Histone Deacetylase-Mediated Changes in Gene ExpressionCharacterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases.Cancer models in Caenorhabditis elegans.Cell division and targeted cell cycle arrest opens and stabilizes basement membrane gaps.The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis.C. elegans CAND-1 regulates cullin neddylation, cell proliferation and morphogenesis in specific tissuesCell type-dependent requirement for PIP box-regulated Cdt1 destruction during S phase.Cullin-4A·DNA damage-binding protein 1 E3 ligase complex targets tumor suppressor RASSF1A for degradation during mitosis.Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligaseStealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy.DDB2, DDB1A and DET1 exhibit complex interactions during Arabidopsis development.Cdt1 degradation to prevent DNA re-replication: conserved and non-conserved pathways.C. elegans MCM-4 is a general DNA replication and checkpoint component with an epidermis-specific requirement for growth and viability.Morphogenesis of the caenorhabditis elegans vulva.The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing.The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegansThe β-sliding clamp directs the localization of HdaA to the replisome in Caulobacter crescentus.The ubiquitin proteasome system in Caenorhabditis elegans and its regulation.CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans.DNA replication licensing control and rereplication prevention.CRL Ubiquitin Ligases and DNA Damage Response.Nucleotide Excision Repair in Caenorhabditis elegans.Docking of a specialized PIP Box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4Cdt2C. elegans CUL-4 prevents rereplication by promoting the nuclear export of CDC-6 via a CKI-1-dependent pathwayCdt1 proteolysis is promoted by dual PIP degrons and is modulated by PCNA ubiquitylation.
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The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex
description
2006 nî lūn-bûn
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
@zh-hk
2006年論文
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2006年論文
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2006年论文
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2006年论文
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name
The Caenorhabditis elegans rep ...... ion by the CUL-4/DDB-1 complex
@ast
The Caenorhabditis elegans rep ...... ion by the CUL-4/DDB-1 complex
@en
type
label
The Caenorhabditis elegans rep ...... ion by the CUL-4/DDB-1 complex
@ast
The Caenorhabditis elegans rep ...... ion by the CUL-4/DDB-1 complex
@en
prefLabel
The Caenorhabditis elegans rep ...... ion by the CUL-4/DDB-1 complex
@ast
The Caenorhabditis elegans rep ...... ion by the CUL-4/DDB-1 complex
@en
P2860
P356
P1476
The Caenorhabditis elegans rep ...... ion by the CUL-4/DDB-1 complex
@en
P2093
Edward T Kipreos
Youngjo Kim
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P304
P356
10.1128/MCB.00736-06
P407
P577
2006-12-04T00:00:00Z