Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability
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Multiple functions of microsomal triglyceride transfer proteinMutations of the microsomal triglyceride-transfer-protein gene in abetalipoproteinemiaA common binding site on the microsomal triglyceride transfer protein for apolipoprotein B and protein disulfide isomeraseA novel abetalipoproteinemia genotype. Identification of a missense mutation in the 97-kDa subunit of the microsomal triglyceride transfer protein that prevents complex formation with protein disulfide isomeraseMechanisms of glucosamine-induced suppression of the hepatic assembly and secretion of apolipoprotein B-100-containing lipoproteinsDecreased secretion of very-low-density lipoprotein triacylglycerol and apolipoprotein B is associated with decreased intracellular triacylglycerol lipolysis in hepatocytes derived from rats fed orotic acid or n-3 fatty acidsMicrosomal triglyceride transfer protein and its role in apoB-lipoprotein assemblyDemonstration of a physical interaction between microsomal triglyceride transfer protein and apolipoprotein B during the assembly of ApoB-containing lipoproteinsCardiac expression of microsomal triglyceride transfer protein is increased in obesity and serves to attenuate cardiac triglyceride accumulation.Expression of microsomal triglyceride transfer protein in lipoprotein-synthesizing tissues of the developing chicken embryoAlternative splicing attenuates transgenic expression directed by the apolipoprotein E promoter-enhancer based expression vector pLIV11.A threonine-based targeting signal in the human CD1d cytoplasmic tail controls its functional expressionAnalysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice.Apolipoprotein B100 quality control and the regulation of hepatic very low density lipoprotein secretion.Apolipoprotein B-containing lipoprotein assembly in microsomal triglyceride transfer protein-deficient McA-RH7777 cells.A polymorphism in the microsomal triglyceride transfer protein can predict the response to antiviral therapy in Egyptian patients with chronic hepatitis C virus genotype 4 infectionMice that produce ApoB100 lipoproteins in the RPE do not develop drusen yet are still a valuable experimental systemACAT2 stimulates cholesteryl ester secretion in apoB-containing lipoproteins.Complexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteins.Murine mammary-derived cells secrete the N-terminal 41% of human apolipoprotein B on high density lipoprotein-sized lipoproteins containing a triacylglycerol-rich core.Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins.Regulation of lipoprotein assembly, secretion and fatty acid β-oxidation by Krüppel-like transcription factor, klf-3.Protein disulfide isomerases contribute differentially to the endoplasmic reticulum-associated degradation of apolipoprotein B and other substratesMicrosomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells.An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells.Polymorphisms of microsomal triglyceride transfer protein in different hepatitis B virus-infected patients.Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E- deficient mouse hepatocytesInsights from human congenital disorders of intestinal lipid metabolism.IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA.Microsomal triglyceride transfer protein activity is not required for the initiation of apolipoprotein B-containing lipoprotein assembly in McA-RH7777 cells.Retina expresses microsomal triglyceride transfer protein: implications for age-related maculopathy.A role for palmitoylation in the quality control, assembly and secretion of apolipoprotein BApolipoprotein B is synthesized in selected human non-hepatic cell lines but not processed into mature lipoprotein.The late addition of core lipids to nascent apolipoprotein B100, resulting in the assembly and secretion of triglyceride-rich lipoproteins, is independent of both microsomal triglyceride transfer protein activity and new triglyceride synthesis.The activity of microsomal triglyceride transfer protein is essential for accumulation of triglyceride within microsomes in McA-RH7777 cells. A unified model for the assembly of very low density lipoproteins.Identification of domains in apolipoprotein B100 that confer a high requirement for the microsomal triglyceride transfer protein.The enzymatic and non-enzymatic roles of protein-disulfide isomerase in apolipoprotein B secretion.Folding of the amino-terminal domain of apolipoprotein B initiates microsomal triglyceride transfer protein-dependent lipid transfer to nascent very low density lipoprotein.Interactions between microsomal triglyceride transfer protein and apolipoprotein B within the endoplasmic reticulum in a heterologous expression system.The amino terminus of apolipoprotein B is necessary but not sufficient for microsomal triglyceride transfer protein responsiveness.
P2860
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P2860
Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Secretion of apolipoprotein B- ...... egulated by lipid availability
@ast
Secretion of apolipoprotein B- ...... egulated by lipid availability
@en
type
label
Secretion of apolipoprotein B- ...... egulated by lipid availability
@ast
Secretion of apolipoprotein B- ...... egulated by lipid availability
@en
prefLabel
Secretion of apolipoprotein B- ...... egulated by lipid availability
@ast
Secretion of apolipoprotein B- ...... egulated by lipid availability
@en
P2093
P2860
P356
P1476
Secretion of apolipoprotein B- ...... egulated by lipid availability
@en
P2093
Mullaney D
Wetterau J
P2860
P304
P356
10.1073/PNAS.91.16.7628
P407
P577
1994-08-01T00:00:00Z