Scattered Deletion of PKD1 in Kidneys Causes a Cystic Snowball Effect and Recapitulates Polycystic Kidney Disease - Wikidata - awgldk - TriplyDB

Scattered Deletion of PKD1 in Kidneys Causes a Cystic Snowball Effect and Recapitulates Polycystic Kidney Disease

Scattered Deletion of PKD1 in Kidneys Causes a Cystic Snowball Effect and Recapitulates Polycystic Kidney Disease

http://www.wikidata.org/entity/Q35658562

about

A polycystin-centric view of cyst formation and disease: the polycystins revisited The Future of Polycystic Kidney Disease Research--As Seen By the 12 Kaplan Awardees.Differences in the timing and magnitude of Pkd1 gene deletion determine the severity of polycystic kidney disease in an orthologous mouse model of ADPKD.Genetics and pathogenesis of autosomal dominant polycystic kidney disease: 20 years on.Variable Cyst Development in Autosomal Dominant Polycystic Kidney Disease: The Biologic Context.Meta-analysis of polycystic kidney disease expression profiles defines strong involvement of injury repair processes.Emerging Therapies for Childhood Polycystic Kidney Disease.Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease.Rapamycin treatment dose-dependently improves the cystic kidney in a new ADPKD mouse model via the mTORC1 and cell-cycle-associated CDK1/cyclin axis.New treatment paradigms for ADPKD: moving towards precision medicine.Canonical Wnt inhibitors ameliorate cystogenesis in a mouse ortholog of human ADPKD.

P2860

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P2860

Scattered Deletion of PKD1 in Kidneys Causes a Cystic Snowball Effect and Recapitulates Polycystic Kidney Disease

http://www.wikidata.org/entity/Q35658562

description

2014 nî lūn-bûn

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Scattered Deletion of PKD1 in ...... ates Polycystic Kidney Disease

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Journal of the American Society of Nephrology

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Scattered Deletion of PKD1 in ...... ates Polycystic Kidney Disease

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P2093

Dorien J M Peters

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Emile de Heer

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Kimberley Veraar

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Malu Zandbergen

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Martijn Breuning

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Susan van den Berg

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P2860

Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

Autosomal dominant polycystic kidney disease: the last 3 years

Generalized lacZ expression with the ROSA26 Cre reporter strain

Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease

Quantification of Cre-mediated recombination by a novel strategy reveals a stable extra-chromosomal deletion-circle in mice.

Evidence of extraordinary growth in the progressive enlargement of renal cysts.

Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways

Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.

Lipocalin 2 is essential for chronic kidney disease progression in mice and humans.

mTORC1/2 and rapamycin in female Han:SPRD rats with polycystic kidney disease.

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10.1681/ASN.2013080864

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6

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26

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Louise van der Weerd

Wouter N Leonhard

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267744788

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